These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

284 related articles for article (PubMed ID: 12852771)

  • 1. Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase.
    Evans GB; Furneaux RH; Lewandowicz A; Schramm VL; Tyler PC
    J Med Chem; 2003 Jul; 46(15):3412-23. PubMed ID: 12852771
    [TBL] [Abstract][Full Text] [Related]  

  • 2. One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase.
    Miles RW; Tyler PC; Furneaux RH; Bagdassarian CK; Schramm VL
    Biochemistry; 1998 Jun; 37(24):8615-21. PubMed ID: 9628722
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases.
    Evans GB; Furneaux RH; Gainsford GJ; Hanson JC; Kicska GA; Sauve AA; Schramm VL; Tyler PC
    J Med Chem; 2003 Jan; 46(1):155-60. PubMed ID: 12502369
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A.
    Singh V; Shi W; Evans GB; Tyler PC; Furneaux RH; Almo SC; Schramm VL
    Biochemistry; 2004 Jan; 43(1):9-18. PubMed ID: 14705926
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Tight binding transition state analogues of purine nucleoside phosphorylase--meaning, design and properties].
    Lewandowicz A
    Postepy Biochem; 2004; 50(3):218-27. PubMed ID: 15822751
    [No Abstract]   [Full Text] [Related]  

  • 6. Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase.
    Lewandowicz A; Shi W; Evans GB; Tyler PC; Furneaux RH; Basso LA; Santos DS; Almo SC; Schramm VL
    Biochemistry; 2003 May; 42(20):6057-66. PubMed ID: 12755607
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of a transition state analogue inhibitor of purine nucleoside phosphorylase via the Mannich reaction.
    Evans GB; Furneaux RH; Tyler PC; Schramm VL
    Org Lett; 2003 Oct; 5(20):3639-40. PubMed ID: 14507192
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase.
    Evans GB; Furneaux RH; Schramm VL; Singh V; Tyler PC
    J Med Chem; 2004 Jun; 47(12):3275-81. PubMed ID: 15163207
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Simplified analogues of immucillin-G retain potent human purine nucleoside phosphorylase inhibitory activity.
    Semeraro T; Lossani A; Botta M; Ghiron C; Alvarez R; Manetti F; Mugnaini C; Valensin S; Focher F; Corelli F
    J Med Chem; 2006 Oct; 49(20):6037-45. PubMed ID: 17004717
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase.
    Evans GB; Furneaux RH; Lewandowicz A; Schramm VL; Tyler PC
    J Med Chem; 2003 Nov; 46(24):5271-6. PubMed ID: 14613329
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Azetidine based transition state analogue inhibitors of N-ribosyl hydrolases and phosphorylases.
    Evans GB; Furneaux RH; Greatrex B; Murkin AS; Schramm VL; Tyler PC
    J Med Chem; 2008 Feb; 51(4):948-56. PubMed ID: 18251493
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase.
    Kicska GA; Tyler PC; Evans GB; Furneaux RH; Shi W; Fedorov A; Lewandowicz A; Cahill SM; Almo SC; Schramm VL
    Biochemistry; 2002 Dec; 41(49):14489-98. PubMed ID: 12463747
    [TBL] [Abstract][Full Text] [Related]  

  • 13. L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase.
    Rinaldo-Matthis A; Murkin AS; Ramagopal UA; Clinch K; Mee SP; Evans GB; Tyler PC; Furneaux RH; Almo SC; Schramm VL
    J Am Chem Soc; 2008 Jan; 130(3):842-4. PubMed ID: 18154341
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor-Part I.
    Kamath VP; Xue J; Juarez-Brambila JJ; Morris CB; Ganorkar R; Morris PE
    Bioorg Med Chem Lett; 2009 May; 19(10):2624-6. PubMed ID: 19386498
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases.
    Sauve AA; Cahill SM; Zech SG; Basso LA; Lewandowicz A; Santos DS; Grubmeyer C; Evans GB; Furneaux RH; Tyler PC; McDermott A; Girvin ME; Schramm VL
    Biochemistry; 2003 May; 42(19):5694-705. PubMed ID: 12741826
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor-Part II.
    Kamath VP; Xue J; Juarez-Brambila JJ
    Bioorg Med Chem Lett; 2009 May; 19(10):2627-9. PubMed ID: 19386496
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Assignment of downfield proton resonances in purine nucleoside phosphorylase immucillin-H complex by saturation-transferred NOEs.
    Deng H; Lewandowicz A; Cahill SM; Furneaux RH; Tyler PC; Girvin ME; Callender RH; Schramm VL
    Biochemistry; 2004 Feb; 43(7):1980-7. PubMed ID: 14967038
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure of human PNP complexed with ligands.
    Canduri F; Silva RG; dos Santos DM; Palma MS; Basso LA; Santos DS; de Azevedo WF
    Acta Crystallogr D Biol Crystallogr; 2005 Jul; 61(Pt 7):856-62. PubMed ID: 15983407
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New catalytic mechanism for human purine nucleoside phosphorylase.
    Canduri F; Fadel V; Basso LA; Palma MS; Santos DS; de Azevedo WF
    Biochem Biophys Res Commun; 2005 Feb; 327(3):646-9. PubMed ID: 15649395
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enzymatic transition states: thermodynamics, dynamics and analogue design.
    Schramm VL
    Arch Biochem Biophys; 2005 Jan; 433(1):13-26. PubMed ID: 15581562
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.