120 related articles for article (PubMed ID: 12852946)
1. Comparative molecular field analysis (CoMFA) of phthalazine derivatives as phosphodiesterase IV inhibitors.
Chakraborti AK; Gopalakrishnan B; Sobhia ME; Malde A
Bioorg Med Chem Lett; 2003 Aug; 13(15):2473-9. PubMed ID: 12852946
[TBL] [Abstract][Full Text] [Related]
2. 3D-QSAR studies of indole derivatives as phosphodiesterase IV inhibitors.
Chakraborti AK; Gopalakrishnan B; Sobhia ME; Malde A
Eur J Med Chem; 2003; 38(11-12):975-82. PubMed ID: 14642329
[TBL] [Abstract][Full Text] [Related]
3. The synthesis and biological evaluation of a novel series of phthalazine PDE4 inhibitors I.
Napoletano M; Norcini G; Pellacini F; Marchini F; Morazzoni G; Ferlenga P; Pradella L
Bioorg Med Chem Lett; 2000 Oct; 10(19):2235-8. PubMed ID: 11012037
[TBL] [Abstract][Full Text] [Related]
4. Phthalazine PDE4 inhibitors. Part 3: the synthesis and in vitro evaluation of derivatives with a hydrogen bond acceptor.
Napoletano M; Norcini G; Pellacini F; Marchini F; Morazzoni G; Fattori R; Ferlenga P; Pradella L
Bioorg Med Chem Lett; 2002 Jan; 12(1):5-8. PubMed ID: 11738561
[TBL] [Abstract][Full Text] [Related]
5. Phthalazine PDE IV inhibitors: conformational study of some 6-methoxy-1,4-disubstituted derivatives.
Haack T; Fattori R; Napoletano M; Pellacini F; Fronza G; Raffaini G; Ganazzoli F
Bioorg Med Chem; 2005 Jul; 13(14):4425-33. PubMed ID: 15927474
[TBL] [Abstract][Full Text] [Related]
6. CoMFA of benzyl derivatives of 2,1,3-benzo and benzothieno[3,2-alpha]thiadiazine 2,2-dioxides: clues for the design of phosphodiesterase 7 inhibitors.
Castro A; Abasolo MI; Gil C; Segarra V; Martinez A
Eur J Med Chem; 2001 Apr; 36(4):333-8. PubMed ID: 11461758
[TBL] [Abstract][Full Text] [Related]
7. 3D-QSAR studies on thieno[3,2-d]pyrimidines as phosphodiesterase IV inhibitors.
Chakraborti AK; Gopalakrishnan B; Sobhia ME; Malde A
Bioorg Med Chem Lett; 2003 Apr; 13(8):1403-8. PubMed ID: 12668000
[TBL] [Abstract][Full Text] [Related]
8. Phthalazine PDE4 inhibitors. Part 2: the synthesis and biological evaluation of 6-methoxy-1,4-disubstituted derivatives.
Napoletano M; Norcini G; Pellacini F; Marchini F; Morazzoni G; Ferlenga P; Pradella L
Bioorg Med Chem Lett; 2001 Jan; 11(1):33-7. PubMed ID: 11140727
[TBL] [Abstract][Full Text] [Related]
9. Quaternary substituted PDE IV inhibitors II: the synthesis and in vitro evaluation of a novel series of gamma-lactams.
Hulme C; Moriarty K; Huang FC; Mason J; McGarry D; Labaudiniere R; Souness J; Djuric S
Bioorg Med Chem Lett; 1998 Feb; 8(4):399-404. PubMed ID: 9871693
[TBL] [Abstract][Full Text] [Related]
10. CoMFA and CoMSIA 3D-quantitative structure-activity relationship model on benzodiazepine derivatives, inhibitors of phosphodiesterase IV.
Ducrot P; Andrianjara CR; Wrigglesworth R
J Comput Aided Mol Des; 2001 Sep; 15(9):767-85. PubMed ID: 11776290
[TBL] [Abstract][Full Text] [Related]
11. Quinazolines: combined type 3 and 4 phosphodiesterase inhibitors.
Charpiot B; Brun J; Donze I; Naef R; Stefani M; Mueller T
Bioorg Med Chem Lett; 1998 Oct; 8(20):2891-6. PubMed ID: 9873643
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and biological studies of catechol ether type derivatives as potential phosphodiesterase (PDE) IV inhibitors.
Rhee CK; Kim JH; Suh BC; Xiang MX; Youn YS; Bang WY; Kim E; Shin JK; Lee Y
Arch Pharm Res; 1999 Apr; 22(2):202-7. PubMed ID: 10230513
[TBL] [Abstract][Full Text] [Related]
13. Quaternary substituted PDE4 inhibitors I: the synthesis and in vitro evaluation of a novel series of oxindoles.
Hulme C; Poli GB; Huang FC; Souness JE; Djuric SW
Bioorg Med Chem Lett; 1998 Jan; 8(2):175-8. PubMed ID: 9871649
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and evaluation of a novel series of phosphodiesterase IV inhibitors. A potential treatment for asthma.
Beasley SC; Cooper N; Gowers L; Gregory JP; Haughan AF; Hellewell PG; Macari D; Miotla J; Montana JG; Morgan T; Naylor R; Runcie KA; Tuladhar B; Warneck JB
Bioorg Med Chem Lett; 1998 Oct; 8(19):2629-34. PubMed ID: 9873593
[TBL] [Abstract][Full Text] [Related]
15. Substituted 2-pyridinemethanol derivatives as potent and selective phosphodiesterase-4 inhibitors.
Ducharme Y; Friesen RW; Blouin M; Côté B; Dubé D; Ethier D; Frenette R; Laliberté F; Mancini JA; Masson P; Styhler A; Young RN; Girard Y
Bioorg Med Chem Lett; 2003 Jun; 13(11):1923-6. PubMed ID: 12749899
[TBL] [Abstract][Full Text] [Related]
16. Synthetic studies on selective type 4 phosphodiesterase (PDE 4) inhibitors. 1. Structure-activity relationships and pharmacological evaluation of 1,8-naphthyridin-2(1H)-one derivatives.
Takayama K; Iwata M; Hisamichi H; Okamoto Y; Aoki M; Niwa A
Chem Pharm Bull (Tokyo); 2002 Aug; 50(8):1050-9. PubMed ID: 12192136
[TBL] [Abstract][Full Text] [Related]
17. Immunosuppressive and anti-inflammatory effects of cyclic AMP phosphodiesterase (PDE) type 4 inhibitors.
Souness JE; Aldous D; Sargent C
Immunopharmacology; 2000 May; 47(2-3):127-62. PubMed ID: 10878287
[No Abstract] [Full Text] [Related]
18. Molecular modeling studies of pyridopurinone derivatives--potential phosphodiesterase 5 inhibitors.
Srivani P; Srinivas E; Raghu R; Sastry GN
J Mol Graph Model; 2007 Jul; 26(1):378-90. PubMed ID: 17307372
[TBL] [Abstract][Full Text] [Related]
19. Syntheses and evaluation of pyrido[2,3-dlpyrimidine-2,4-diones as PDE 4 inhibitors.
Nam G; Yoon CM; Kim E; Rhee CK; Kim JH; Shin JH; Kim SH
Bioorg Med Chem Lett; 2001 Mar; 11(5):611-4. PubMed ID: 11266153
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and potential anti-inflammatory activity of some tetrahydrophthalazinones.
Gouault N; Pinel B; Cupif JF; Depince A; Martin-Chouly CA; Belleguic C; David M
J Enzyme Inhib Med Chem; 2004 Dec; 19(6):475-80. PubMed ID: 15662951
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]