119 related articles for article (PubMed ID: 12855553)
1. Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development.
Stove V; Naessens E; Stove C; Swigut T; Plum J; Verhasselt B
Blood; 2003 Oct; 102(8):2925-32. PubMed ID: 12855553
[TBL] [Abstract][Full Text] [Related]
2. Activation of p21-activated kinase 2 and its association with Nef are conserved in murine cells but are not sufficient to induce an AIDS-like disease in CD4C/HIV transgenic mice.
Vincent P; Priceputu E; Kay D; Saksela K; Jolicoeur P; Hanna Z
J Biol Chem; 2006 Mar; 281(11):6940-54. PubMed ID: 16407193
[TBL] [Abstract][Full Text] [Related]
3. A hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2.
Agopian K; Wei BL; Garcia JV; Gabuzda D
J Virol; 2006 Mar; 80(6):3050-61. PubMed ID: 16501114
[TBL] [Abstract][Full Text] [Related]
4. In vivo mutational analysis of the N-terminal region of HIV-1 Nef reveals critical motifs for the development of an AIDS-like disease in CD4C/HIV transgenic mice.
Hanna Z; Priceputu E; Kay DG; Poudrier J; Chrobak P; Jolicoeur P
Virology; 2004 Oct; 327(2):273-86. PubMed ID: 15351215
[TBL] [Abstract][Full Text] [Related]
5. The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling.
Arold S; Franken P; Strub MP; Hoh F; Benichou S; Benarous R; Dumas C
Structure; 1997 Oct; 5(10):1361-72. PubMed ID: 9351809
[TBL] [Abstract][Full Text] [Related]
6. Specific and distinct determinants mediate membrane binding and lipid raft incorporation of HIV-1(SF2) Nef.
Giese SI; Woerz I; Homann S; Tibroni N; Geyer M; Fackler OT
Virology; 2006 Nov; 355(2):175-91. PubMed ID: 16916529
[TBL] [Abstract][Full Text] [Related]
7. The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes.
Greenberg ME; Iafrate AJ; Skowronski J
EMBO J; 1998 May; 17(10):2777-89. PubMed ID: 9582271
[TBL] [Abstract][Full Text] [Related]
8. Hck SH3 domain-dependent abrogation of Nef-induced class 1 MHC down-regulation.
Chang AH; O'Shaughnessy MV; Jirik FR
Eur J Immunol; 2001 Aug; 31(8):2382-7. PubMed ID: 11500821
[TBL] [Abstract][Full Text] [Related]
9. CD4 and MHC-I downregulation are conserved in primary HIV-1 Nef alleles from brain and lymphoid tissues, but Pak2 activation is highly variable.
Agopian K; Wei BL; Garcia JV; Gabuzda D
Virology; 2007 Feb; 358(1):119-35. PubMed ID: 16979207
[TBL] [Abstract][Full Text] [Related]
10. Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complex.
Brown A; Wang X; Sawai E; Cheng-Mayer C
J Virol; 1999 Dec; 73(12):9899-907. PubMed ID: 10559302
[TBL] [Abstract][Full Text] [Related]
11. HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway.
Blagoveshchenskaya AD; Thomas L; Feliciangeli SF; Hung CH; Thomas G
Cell; 2002 Dec; 111(6):853-66. PubMed ID: 12526811
[TBL] [Abstract][Full Text] [Related]
12. Oligomerization is required for HIV-1 Nef-induced activation of the Src family protein-tyrosine kinase, Hck.
Ye H; Choi HJ; Poe J; Smithgall TE
Biochemistry; 2004 Dec; 43(50):15775-84. PubMed ID: 15595833
[TBL] [Abstract][Full Text] [Related]
13. Design and use of an inducibly activated human immunodeficiency virus type 1 Nef to study immune modulation.
Walk SF; Alexander M; Maier B; Hammarskjold ML; Rekosh DM; Ravichandran KS
J Virol; 2001 Jan; 75(2):834-43. PubMed ID: 11134296
[TBL] [Abstract][Full Text] [Related]
14. Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors.
Kirchhoff F; Schindler M; Bailer N; Renkema GH; Saksela K; Knoop V; Müller-Trutwin MC; Santiago ML; Bibollet-Ruche F; Dittmar MT; Heeney JL; Hahn BH; Münch J
J Virol; 2004 Jul; 78(13):6864-74. PubMed ID: 15194762
[TBL] [Abstract][Full Text] [Related]
15. The HIV Nef protein alters Ca(2+) signaling in myelomonocytic cells through SH3-mediated protein-protein interactions.
Foti M; Cartier L; Piguet V; Lew DP; Carpentier JL; Trono D; Krause KH
J Biol Chem; 1999 Dec; 274(49):34765-72. PubMed ID: 10574946
[TBL] [Abstract][Full Text] [Related]
16. SH3-Domain binding function of HIV-1 Nef is required for association with a PAK-related kinase.
Manninen A; Hiipakka M; Vihinen M; Lu W; Mayer BJ; Saksela K
Virology; 1998 Oct; 250(2):273-82. PubMed ID: 9792838
[TBL] [Abstract][Full Text] [Related]
17. HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes.
Piguet V; Wan L; Borel C; Mangasarian A; Demaurex N; Thomas G; Trono D
Nat Cell Biol; 2000 Mar; 2(3):163-7. PubMed ID: 10707087
[TBL] [Abstract][Full Text] [Related]
18. HIV and SIV Nef modulate signal transduction and protein sorting in T cells.
Skowronski J; Greenberg ME; Lock M; Mariani R; Salghetti S; Swigut T; Iafrate AJ
Cold Spring Harb Symp Quant Biol; 1999; 64():453-63. PubMed ID: 11232322
[No Abstract] [Full Text] [Related]
19. Lentivirus Nef specifically activates Pak2.
Arora VK; Molina RP; Foster JL; Blakemore JL; Chernoff J; Fredericksen BL; Garcia JV
J Virol; 2000 Dec; 74(23):11081-7. PubMed ID: 11070003
[TBL] [Abstract][Full Text] [Related]
20. Interactions of HIV-1 NEF with cellular signal transducing proteins.
Renkema GH; Saksela K
Front Biosci; 2000 Feb; 5():D268-83. PubMed ID: 10704155
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]