These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 12855660)

  • 1. The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo.
    Place AE; Suh N; Williams CR; Risingsong R; Honda T; Honda Y; Gribble GW; Leesnitzer LM; Stimmel JB; Willson TM; Rosen E; Sporn MB
    Clin Cancer Res; 2003 Jul; 9(7):2798-806. PubMed ID: 12855660
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of peroxisome proliferator-activated receptor gamma by a novel synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest and apoptosis in breast cancer cells.
    Lapillonne H; Konopleva M; Tsao T; Gold D; McQueen T; Sutherland RL; Madden T; Andreeff M
    Cancer Res; 2003 Sep; 63(18):5926-39. PubMed ID: 14522919
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid and related compounds inhibit growth of colon cancer cells through peroxisome proliferator-activated receptor gamma-dependent and -independent pathways.
    Chintharlapalli S; Papineni S; Konopleva M; Andreef M; Samudio I; Safe S
    Mol Pharmacol; 2005 Jul; 68(1):119-28. PubMed ID: 15798084
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Growth-inhibitory effect of a novel synthetic triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, on ovarian carcinoma cell lines not dependent on peroxisome proliferator-activated receptor-gamma expression.
    Melichar B; Konopleva M; Hu W; Melicharova K; Andreeff M; Freedman RS
    Gynecol Oncol; 2004 Apr; 93(1):149-54. PubMed ID: 15047229
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel synthetic pyridyl analogues of CDDO-Imidazolide are useful new tools in cancer prevention.
    Cao M; Onyango EO; Williams CR; Royce DB; Gribble GW; Sporn MB; Liby KT
    Pharmacol Res; 2015 Oct; 100():135-47. PubMed ID: 26238177
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole.
    Yates MS; Kwak MK; Egner PA; Groopman JD; Bodreddigari S; Sutter TR; Baumgartner KJ; Roebuck BD; Liby KT; Yore MM; Honda T; Gribble GW; Sporn MB; Kensler TW
    Cancer Res; 2006 Feb; 66(4):2488-94. PubMed ID: 16489057
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells.
    Hyer ML; Croxton R; Krajewska M; Krajewski S; Kress CL; Lu M; Suh N; Sporn MB; Cryns VL; Zapata JM; Reed JC
    Cancer Res; 2005 Jun; 65(11):4799-808. PubMed ID: 15930300
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Peroxisome proliferator-activated receptor-gamma-independent repression of collagenase gene expression by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and prostaglandin 15-deoxy-delta(12,14) J2: a role for Smad signaling.
    Mix KS; Coon CI; Rosen ED; Suh N; Sporn MB; Brinckerhoff CE
    Mol Pharmacol; 2004 Feb; 65(2):309-18. PubMed ID: 14742672
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer.
    Hyer ML; Shi R; Krajewska M; Meyer C; Lebedeva IV; Fisher PB; Reed JC
    Cancer Res; 2008 Apr; 68(8):2927-33. PubMed ID: 18413762
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthetic triterpenoids enhance transforming growth factor beta/Smad signaling.
    Suh N; Roberts AB; Birkey Reffey S; Miyazono K; Itoh S; ten Dijke P; Heiss EH; Place AE; Risingsong R; Williams CR; Honda T; Gribble GW; Sporn MB
    Cancer Res; 2003 Mar; 63(6):1371-6. PubMed ID: 12649201
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CDDO-Im is a stimulator of megakaryocytic differentiation.
    Petronelli A; Pelosi E; Santoro S; Saulle E; Cerio AM; Mariani G; Labbaye C; Testa U
    Leuk Res; 2011 Apr; 35(4):534-44. PubMed ID: 21035854
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The synthetic triterpenoid CDDO-imidazolide induces monocytic differentiation by activating the Smad and ERK signaling pathways in HL60 leukemia cells.
    Ji Y; Lee HJ; Goodman C; Uskokovic M; Liby K; Sporn M; Suh N
    Mol Cancer Ther; 2006 Jun; 5(6):1452-8. PubMed ID: 16818503
    [TBL] [Abstract][Full Text] [Related]  

  • 13. High sensitivity of ovarian cancer cells to the synthetic triterpenoid CDDO-Imidazolide.
    Petronelli A; Saulle E; Pasquini L; Petrucci E; Mariani G; Biffoni M; Ferretti G; Scambia G; Benedetti-Panici P; Greggi S; Cognetti F; Russo MA; Sporn M; Testa U
    Cancer Lett; 2009 Sep; 282(2):214-28. PubMed ID: 19364626
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) induces apoptosis of human diffuse large B-cell lymphoma cells through a peroxisome proliferator-activated receptor gamma-independent pathway.
    Ray DM; Morse KM; Hilchey SP; Garcia TM; Felgar RE; Maggirwar SB; Phipps RP; Bernstein SH
    Exp Hematol; 2006 Sep; 34(9):1202-11. PubMed ID: 16939813
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CDDO-Me inhibits proliferation, induces apoptosis, down-regulates Akt, mTOR, NF-kappaB and NF-kappaB-regulated antiapoptotic and proangiogenic proteins in TRAMP prostate cancer cells.
    Deeb D; Gao X; Dulchavsky SA; Gautam SC
    J Exp Ther Oncol; 2008; 7(1):31-9. PubMed ID: 18472640
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The novel synthetic oleanane triterpenoid CDDO (2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid) induces apoptosis in Mycosis fungoides/Sézary syndrome cells.
    Zhang C; Ni X; Konopleva M; Andreeff M; Duvic M
    J Invest Dermatol; 2004 Aug; 123(2):380-7. PubMed ID: 15245439
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A synthetic triterpenoid, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator-activated receptor gamma.
    Wang Y; Porter WW; Suh N; Honda T; Gribble GW; Leesnitzer LM; Plunket KD; Mangelsdorf DJ; Blanchard SG; Willson TM; Sporn MB
    Mol Endocrinol; 2000 Oct; 14(10):1550-6. PubMed ID: 11043571
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytoprotection of human endothelial cells against oxidative stress by 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole (CDDO-Im): application of systems biology to understand the mechanism of action.
    Wang X; Bynum JA; Stavchansky S; Bowman PD
    Eur J Pharmacol; 2014 Jul; 734():122-31. PubMed ID: 24703885
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity.
    Suh N; Wang Y; Honda T; Gribble GW; Dmitrovsky E; Hickey WF; Maue RA; Place AE; Porter DM; Spinella MJ; Williams CR; Wu G; Dannenberg AJ; Flanders KC; Letterio JJ; Mangelsdorf DJ; Nathan CF; Nguyen L; Porter WW; Ren RF; Roberts AB; Roche NS; Subbaramaiah K; Sporn MB
    Cancer Res; 1999 Jan; 59(2):336-41. PubMed ID: 9927043
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CDDO-imidazolide induces DNA damage, G2/M arrest and apoptosis in BRCA1-mutated breast cancer cells.
    Kim EH; Deng CX; Sporn MB; Liby KT
    Cancer Prev Res (Phila); 2011 Mar; 4(3):425-34. PubMed ID: 21372041
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.