These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

316 related articles for article (PubMed ID: 12857747)

  • 1. Allosteric activation of PTEN phosphatase by phosphatidylinositol 4,5-bisphosphate.
    Campbell RB; Liu F; Ross AH
    J Biol Chem; 2003 Sep; 278(36):33617-20. PubMed ID: 12857747
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phospholipid-binding sites of phosphatase and tensin homolog (PTEN): exploring the mechanism of phosphatidylinositol 4,5-bisphosphate activation.
    Wei Y; Stec B; Redfield AG; Weerapana E; Roberts MF
    J Biol Chem; 2015 Jan; 290(3):1592-606. PubMed ID: 25429968
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate.
    Iwasaki H; Murata Y; Kim Y; Hossain MI; Worby CA; Dixon JE; McCormack T; Sasaki T; Okamura Y
    Proc Natl Acad Sci U S A; 2008 Jun; 105(23):7970-5. PubMed ID: 18524949
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antagonism of PI 3-kinase-dependent signalling pathways by the tumour suppressor protein, PTEN.
    Downes CP; Bennett D; McConnachie G; Leslie NR; Pass I; MacPhee C; Patel L; Gray A
    Biochem Soc Trans; 2001 Nov; 29(Pt 6):846-51. PubMed ID: 11709086
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PTEN phosphatase selectively binds phosphoinositides and undergoes structural changes.
    Redfern RE; Redfern D; Furgason ML; Munson M; Ross AH; Gericke A
    Biochemistry; 2008 Feb; 47(7):2162-71. PubMed ID: 18220422
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The tumour-suppressor function of PTEN requires an N-terminal lipid-binding motif.
    Walker SM; Leslie NR; Perera NM; Batty IH; Downes CP
    Biochem J; 2004 Apr; 379(Pt 2):301-7. PubMed ID: 14711368
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of the PTEN phosphatase.
    Gericke A; Munson M; Ross AH
    Gene; 2006 Jun; 374():1-9. PubMed ID: 16675164
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A PTEN-like phosphatase with a novel substrate specificity.
    Pagliarini DJ; Worby CA; Dixon JE
    J Biol Chem; 2004 Sep; 279(37):38590-6. PubMed ID: 15247229
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphoinositide 5- and 3-phosphatase activities of a voltage-sensing phosphatase in living cells show identical voltage dependence.
    Keum D; Kruse M; Kim DI; Hille B; Suh BC
    Proc Natl Acad Sci U S A; 2016 Jun; 113(26):E3686-95. PubMed ID: 27222577
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Kinetics of PTEN-mediated PI(3,4,5)P3 hydrolysis on solid supported membranes.
    Liu C; Deb S; Ferreira VS; Xu E; Baumgart T
    PLoS One; 2018; 13(2):e0192667. PubMed ID: 29447222
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The C-terminal tail inhibitory phosphorylation sites of PTEN regulate its intrinsic catalytic activity and the kinetics of its binding to phosphatidylinositol-4,5-bisphosphate.
    Chia YC; Catimel B; Lio DS; Ang CS; Peng B; Wu H; Zhu HJ; Cheng HC
    Arch Biochem Biophys; 2015 Dec; 587():48-60. PubMed ID: 26471078
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel mechanism of PTEN regulation by its phosphatidylinositol 4,5-bisphosphate binding motif is critical for chemotaxis.
    Iijima M; Huang YE; Luo HR; Vazquez F; Devreotes PN
    J Biol Chem; 2004 Apr; 279(16):16606-13. PubMed ID: 14764604
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel class of PTEN protein in Arabidopsis displays unusual phosphoinositide phosphatase activity and efficiently binds phosphatidic acid.
    Pribat A; Sormani R; Rousseau-Gueutin M; Julkowska MM; Testerink C; Joubès J; Castroviejo M; Laguerre M; Meyer C; Germain V; Rothan C
    Biochem J; 2012 Jan; 441(1):161-71. PubMed ID: 21864294
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions.
    Leslie NR; Bennett D; Gray A; Pass I; Hoang-Xuan K; Downes CP
    Biochem J; 2001 Jul; 357(Pt 2):427-35. PubMed ID: 11439092
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A mutant form of PTEN linked to autism.
    Redfern RE; Daou MC; Li L; Munson M; Gericke A; Ross AH
    Protein Sci; 2010 Oct; 19(10):1948-56. PubMed ID: 20718038
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of cell migration by the C2 domain of the tumor suppressor PTEN.
    Raftopoulou M; Etienne-Manneville S; Self A; Nicholls S; Hall A
    Science; 2004 Feb; 303(5661):1179-81. PubMed ID: 14976311
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synaptojanin inhibition of phospholipase D activity by hydrolysis of phosphatidylinositol 4,5-bisphosphate.
    Chung JK; Sekiya F; Kang HS; Lee C; Han JS; Kim SR; Bae YS; Morris AJ; Rhee SG
    J Biol Chem; 1997 Jun; 272(25):15980-5. PubMed ID: 9188500
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors.
    Freeburn RW; Wright KL; Burgess SJ; Astoul E; Cantrell DA; Ward SG
    J Immunol; 2002 Nov; 169(10):5441-50. PubMed ID: 12421919
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PTEN 2, a Golgi-associated testis-specific homologue of the PTEN tumor suppressor lipid phosphatase.
    Wu Y; Dowbenko D; Pisabarro MT; Dillard-Telm L; Koeppen H; Lasky LA
    J Biol Chem; 2001 Jun; 276(24):21745-53. PubMed ID: 11279206
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Defining the membrane-associated state of the PTEN tumor suppressor protein.
    Lumb CN; Sansom MS
    Biophys J; 2013 Feb; 104(3):613-21. PubMed ID: 23442912
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.