BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 12858347)

  • 1. Overexpression of interleukin-2 receptor alpha in a human squamous cell carcinoma of the head and neck cell line is associated with increased proliferation, drug resistance, and transforming ability.
    Kuhn DJ; Smith DM; Pross S; Whiteside TL; Dou QP
    J Cell Biochem; 2003 Jul; 89(4):824-36. PubMed ID: 12858347
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Direct inhibition of interleukin-2 receptor alpha-mediated signaling pathway induces G1 arrest and apoptosis in human head-and-neck cancer cells.
    Kuhn DJ; Dou QP
    J Cell Biochem; 2005 May; 95(2):379-90. PubMed ID: 15779002
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells.
    Di Gennaro E; Barbarino M; Bruzzese F; De Lorenzo S; Caraglia M; Abbruzzese A; Avallone A; Comella P; Caponigro F; Pepe S; Budillon A
    J Cell Physiol; 2003 Apr; 195(1):139-50. PubMed ID: 12599217
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p27Kip1 accumulation by inhibition of proteasome function induces apoptosis in oral squamous cell carcinoma cells.
    Kudo Y; Takata T; Ogawa I; Kaneda T; Sato S; Takekoshi T; Zhao M; Miyauchi M; Nikai H
    Clin Cancer Res; 2000 Mar; 6(3):916-23. PubMed ID: 10741716
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cyclin-dependent kinase inhibitor (roscovitine) suppresses growth and induces apoptosis by regulating Bcl-x in head and neck squamous cell carcinoma cells.
    Mihara M; Shintani S; Kiyota A; Matsumura T; Wong DT
    Int J Oncol; 2002 Jul; 21(1):95-101. PubMed ID: 12063555
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Heterogeneity in interleukin-13 receptor expression and subunit structure in squamous cell carcinoma of head and neck: differential sensitivity to chimeric fusion proteins comprised of interleukin-13 and a mutated form of Pseudomonas exotoxin.
    Joshi BH; Kawakami K; Leland P; Puri RK
    Clin Cancer Res; 2002 Jun; 8(6):1948-56. PubMed ID: 12060640
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein levels of p21, p27, cyclin E and Bax predict sensitivity to cisplatin and paclitaxel in head and neck squamous cell carcinomas.
    Taguchi T; Kato Y; Baba Y; Nishimura G; Tanigaki Y; Horiuchi C; Mochimatsu I; Tsukuda M
    Oncol Rep; 2004 Feb; 11(2):421-6. PubMed ID: 14719078
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inducible NO synthase confers chemoresistance in head and neck cancer by modulating survivin.
    Fetz V; Bier C; Habtemichael N; Schuon R; Schweitzer A; Kunkel M; Engels K; Kovács AF; Schneider S; Mann W; Stauber RH; Knauer SK
    Int J Cancer; 2009 May; 124(9):2033-41. PubMed ID: 19130609
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts.
    An B; Goldfarb RH; Siman R; Dou QP
    Cell Death Differ; 1998 Dec; 5(12):1062-75. PubMed ID: 9894613
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Receptors for interleukin 2 on human squamous cell carcinoma cell lines and tumor in situ.
    Weidmann E; Sacchi M; Plaisance S; Heo DS; Yasumura S; Lin WC; Johnson JT; Herberman RB; Azzarone B; Whiteside TL
    Cancer Res; 1992 Nov; 52(21):5963-70. PubMed ID: 1394222
    [TBL] [Abstract][Full Text] [Related]  

  • 11. EGFR blockade by tyrosine kinase inhibitor or monoclonal antibody inhibits growth, directs terminal differentiation and induces apoptosis in the human squamous cell carcinoma HN5.
    Modjtahedi H; Affleck K; Stubberfield C; Dean C
    Int J Oncol; 1998 Aug; 13(2):335-42. PubMed ID: 9664130
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genistein induced molecular changes in a squamous cell carcinoma of the head and neck cell line.
    Alhasan SA; Ensley JF; Sarkar FH
    Int J Oncol; 2000 Feb; 16(2):333-8. PubMed ID: 10639578
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Perifosine, a novel alkylphospholipid, induces p21(WAF1) expression in squamous carcinoma cells through a p53-independent pathway, leading to loss in cyclin-dependent kinase activity and cell cycle arrest.
    Patel V; Lahusen T; Sy T; Sausville EA; Gutkind JS; Senderowicz AM
    Cancer Res; 2002 Mar; 62(5):1401-9. PubMed ID: 11888912
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transcript synthesis and surface expression of the interleukin-2 receptor (alpha-, beta-, and gamma-chain) by normal and malignant myeloid cells.
    Schumann RR; Nakarai T; Gruss HJ; Brach MA; von Arnim U; Kirschning C; Karawajew L; Ludwig WD; Renauld JC; Ritz J; Herrmann F
    Blood; 1996 Mar; 87(6):2419-27. PubMed ID: 8630406
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Critical role of the interleukin 2 (IL-2) receptor gamma-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction.
    Kawahara A; Minami Y; Miyazaki T; Ihle JN; Taniguchi T
    Proc Natl Acad Sci U S A; 1995 Sep; 92(19):8724-8. PubMed ID: 7568005
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Establishment and some characteristics of epoxomicin (a proteasome inhibitor) resistant variants of the human squamous cell carcinoma cell line, A431.
    Ohkawa K; Asakura T; Aoki K; Shibata S; Minami J; Fujiwara C; Sai T; Marushima H; Kuzuu H
    Int J Oncol; 2004 Feb; 24(2):425-33. PubMed ID: 14719120
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Constitutive activation of signal transducers and activators of transcription 3 correlates with cyclin D1 overexpression and may provide a novel prognostic marker in head and neck squamous cell carcinoma.
    Masuda M; Suzui M; Yasumatu R; Nakashima T; Kuratomi Y; Azuma K; Tomita K; Komiyama S; Weinstein IB
    Cancer Res; 2002 Jun; 62(12):3351-5. PubMed ID: 12067972
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deregulated cyclin D1 expression is associated with decreased efficacy of the selective epidermal growth factor receptor tyrosine kinase inhibitor gefitinib in head and neck squamous cell carcinoma cell lines.
    Kalish LH; Kwong RA; Cole IE; Gallagher RM; Sutherland RL; Musgrove EA
    Clin Cancer Res; 2004 Nov; 10(22):7764-74. PubMed ID: 15570011
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro and in vivo characteristics of human squamous cell carcinoma of the head and neck cells engineered to secrete interleukin-2.
    Nagashima S; Reichert TE; Kashii Y; Suminami Y; Chikamatsu K; Whiteside TL
    Cancer Gene Ther; 1997; 4(6):366-76. PubMed ID: 9408607
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacodynamics of taxol in human head and neck tumors.
    Gan Y; Wientjes MG; Schuller DE; Au JL
    Cancer Res; 1996 May; 56(9):2086-93. PubMed ID: 8616855
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.