These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

51 related articles for article (PubMed ID: 12861476)

  • 1. Inhibitors of hepatitis C--a review of the recent patent literature.
    Zhang X
    IDrugs; 2002 Feb; 5(2):154-8. PubMed ID: 12861476
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The design of a potent inhibitor of the hepatitis C virus NS3 protease: BILN 2061--from the NMR tube to the clinic.
    Tsantrizos YS
    Biopolymers; 2004; 76(4):309-23. PubMed ID: 15386268
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Non-HIV antivirals - a review of the recent patent literature.
    Combrink K
    IDrugs; 2002 Aug; 5(8):815-27. PubMed ID: 12802698
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Challenges in modern drug discovery: a case study of boceprevir, an HCV protease inhibitor for the treatment of hepatitis C virus infection.
    Njoroge FG; Chen KX; Shih NY; Piwinski JJ
    Acc Chem Res; 2008 Jan; 41(1):50-9. PubMed ID: 18193821
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vitro antiviral activity of SCH446211 (SCH6), a novel inhibitor of the hepatitis C virus NS3 serine protease.
    Liu R; Abid K; Pichardo J; Pazienza V; Ingravallo P; Kong R; Agrawal S; Bogen S; Saksena A; Cheng KC; Prongay A; Njoroge FG; Baroudy BM; Negro F
    J Antimicrob Chemother; 2007 Jan; 59(1):51-8. PubMed ID: 17151003
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Recruitment of an interferon molecular signaling complex to the mitochondrial membrane: disruption by hepatitis C virus NS3-4A protease.
    Hiscott J; Lacoste J; Lin R
    Biochem Pharmacol; 2006 Nov; 72(11):1477-84. PubMed ID: 16876765
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HCV NS3 serine protease-neutralizing single-chain antibodies isolated by a novel genetic screen.
    Gal-Tanamy M; Zemel R; Berdichevsky Y; Bachmatov L; Tur-Kaspa R; Benhar I
    J Mol Biol; 2005 Apr; 347(5):991-1003. PubMed ID: 15784258
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus.
    Lamarre D; Anderson PC; Bailey M; Beaulieu P; Bolger G; Bonneau P; Bös M; Cameron DR; Cartier M; Cordingley MG; Faucher AM; Goudreau N; Kawai SH; Kukolj G; Lagacé L; LaPlante SR; Narjes H; Poupart MA; Rancourt J; Sentjens RE; St George R; Simoneau B; Steinmann G; Thibeault D; Tsantrizos YS; Weldon SM; Yong CL; Llinàs-Brunet M
    Nature; 2003 Nov; 426(6963):186-9. PubMed ID: 14578911
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Peptidomimetic therapeutic agents targeting the protease enzyme of the human immunodeficiency virus and hepatitis C virus.
    Tsantrizos YS
    Acc Chem Res; 2008 Oct; 41(10):1252-63. PubMed ID: 18681464
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evaluation of a diverse set of potential P1 carboxylic acid bioisosteres in hepatitis C virus NS3 protease inhibitors.
    Rönn R; Gossas T; Sabnis YA; Daoud H; Kerblom E; Danielson UH; Sandström A
    Bioorg Med Chem; 2007 Jun; 15(12):4057-68. PubMed ID: 17449253
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Progress and development of small molecule HCV antivirals.
    Ni ZJ; Wagman AS
    Curr Opin Drug Discov Devel; 2004 Jul; 7(4):446-59. PubMed ID: 15338954
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selective inhibitors of hepatitis C virus replication.
    Neyts J
    Antiviral Res; 2006 Sep; 71(2-3):363-71. PubMed ID: 16843538
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel potent macrocyclic inhibitors of the hepatitis C virus NS3 protease: use of cyclopentane and cyclopentene P2-motifs.
    Bäck M; Johansson PO; Wångsell F; Thorstensson F; Kvarnström I; Ayesa S; Wähling H; Pelcman M; Jansson K; Lindström S; Wallberg H; Classon B; Rydergård C; Vrang L; Hamelink E; Hallberg A; Rosenquist S; Samuelsson B
    Bioorg Med Chem; 2007 Nov; 15(22):7184-202. PubMed ID: 17845856
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Resistance mechanisms in HCV: from evolution to intervention.
    Kim AY; Timm J
    Expert Rev Anti Infect Ther; 2008 Aug; 6(4):463-78. PubMed ID: 18662114
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Establishment of a subgenomic replicon for bovine viral diarrhea virus in Huh-7 cells and modulation of interferon-regulated factor 3-mediated antiviral response.
    Horscroft N; Bellows D; Ansari I; Lai VC; Dempsey S; Liang D; Donis R; Zhong W; Hong Z
    J Virol; 2005 Mar; 79(5):2788-96. PubMed ID: 15708997
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A homogeneous, solid-phase assay for hepatitis C virus RNA-dependent RNA polymerase.
    Wang YK; Rigat KL; Roberts SB; Gao M
    Anal Biochem; 2006 Dec; 359(1):106-11. PubMed ID: 17054898
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Potent inhibitors of HCV-NS3 protease derived from boronic acids.
    Venkatraman S; Wu W; Prongay A; Girijavallabhan V; George Njoroge F
    Bioorg Med Chem Lett; 2009 Jan; 19(1):180-3. PubMed ID: 19022670
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Existing and future therapeutic options for hepatitis C virus infection.
    Bretner M
    Acta Biochim Pol; 2005; 52(1):57-70. PubMed ID: 15827606
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antiviral efficacy of NS3-serine protease inhibitor BILN-2061 in patients with chronic genotype 2 and 3 hepatitis C.
    Reiser M; Hinrichsen H; Benhamou Y; Reesink HW; Wedemeyer H; Avendano C; Riba N; Yong CL; Nehmiz G; Steinmann GG
    Hepatology; 2005 Apr; 41(4):832-5. PubMed ID: 15732092
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sequence analysis of NS3 protease gene in clinical strains of hepatitis C virus.
    Lodrini S; Bagaglio S; Canducci F; De Mitri MS; Andreone P; Loggi E; Lazzarin A; Clementi M; Morsica G
    J Biol Regul Homeost Agents; 2003; 17(2):198-204. PubMed ID: 14518724
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 3.