BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

585 related articles for article (PubMed ID: 12865424)

  • 1. Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids.
    Lee JY; Ye J; Gao Z; Youn HS; Lee WH; Zhao L; Sizemore N; Hwang DH
    J Biol Chem; 2003 Sep; 278(39):37041-51. PubMed ID: 12865424
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1.
    Lee JY; Zhao L; Youn HS; Weatherill AR; Tapping R; Feng L; Lee WH; Fitzgerald KA; Hwang DH
    J Biol Chem; 2004 Apr; 279(17):16971-9. PubMed ID: 14966134
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex.
    Youn HS; Lee JY; Fitzgerald KA; Young HA; Akira S; Hwang DH
    J Immunol; 2005 Sep; 175(5):3339-46. PubMed ID: 16116226
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4.
    Lee JY; Sohn KH; Rhee SH; Hwang D
    J Biol Chem; 2001 May; 276(20):16683-9. PubMed ID: 11278967
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kappa B in endothelial cells.
    Li X; Tupper JC; Bannerman DD; Winn RK; Rhodes CJ; Harlan JM
    Infect Immun; 2003 Aug; 71(8):4414-20. PubMed ID: 12874320
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Micrococci and peptidoglycan activate TLR2-->MyD88-->IRAK-->TRAF-->NIK-->IKK-->NF-kappaB signal transduction pathway that induces transcription of interleukin-8.
    Wang Q; Dziarski R; Kirschning CJ; Muzio M; Gupta D
    Infect Immun; 2001 Apr; 69(4):2270-6. PubMed ID: 11254583
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The pro-atherogenic cytokine interleukin-18 induces CXCL16 expression in rat aortic smooth muscle cells via MyD88, interleukin-1 receptor-associated kinase, tumor necrosis factor receptor-associated factor 6, c-Src, phosphatidylinositol 3-kinase, Akt, c-Jun N-terminal kinase, and activator protein-1 signaling.
    Chandrasekar B; Mummidi S; Valente AJ; Patel DN; Bailey SR; Freeman GL; Hatano M; Tokuhisa T; Jensen LE
    J Biol Chem; 2005 Jul; 280(28):26263-77. PubMed ID: 15890643
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Myeloid differentiation factor 88-dependent post-transcriptional regulation of cyclooxygenase-2 expression by CpG DNA: tumor necrosis factor-alpha receptor-associated factor 6, a diverging point in the Toll-like receptor 9-signaling.
    Yeo SJ; Yoon JG; Yi AK
    J Biol Chem; 2003 Oct; 278(42):40590-600. PubMed ID: 12902324
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages.
    Ojaniemi M; Glumoff V; Harju K; Liljeroos M; Vuori K; Hallman M
    Eur J Immunol; 2003 Mar; 33(3):597-605. PubMed ID: 12616480
    [TBL] [Abstract][Full Text] [Related]  

  • 10. IKK beta and phosphatidylinositol 3-kinase/Akt participate in non-pathogenic Gram-negative enteric bacteria-induced RelA phosphorylation and NF-kappa B activation in both primary and intestinal epithelial cell lines.
    Haller D; Russo MP; Sartor RB; Jobin C
    J Biol Chem; 2002 Oct; 277(41):38168-78. PubMed ID: 12140289
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Murine TOLL-like receptor 4 confers lipopolysaccharide responsiveness as determined by activation of NF kappa B and expression of the inducible cyclooxygenase.
    Rhee SH; Hwang D
    J Biol Chem; 2000 Nov; 275(44):34035-40. PubMed ID: 10952994
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells.
    Medvedev AE; Lentschat A; Wahl LM; Golenbock DT; Vogel SN
    J Immunol; 2002 Nov; 169(9):5209-16. PubMed ID: 12391239
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids.
    Lee JY; Plakidas A; Lee WH; Heikkinen A; Chanmugam P; Bray G; Hwang DH
    J Lipid Res; 2003 Mar; 44(3):479-86. PubMed ID: 12562875
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway.
    Bulut Y; Faure E; Thomas L; Karahashi H; Michelsen KS; Equils O; Morrison SG; Morrison RP; Arditi M
    J Immunol; 2002 Feb; 168(3):1435-40. PubMed ID: 11801686
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling.
    Bulut Y; Faure E; Thomas L; Equils O; Arditi M
    J Immunol; 2001 Jul; 167(2):987-94. PubMed ID: 11441107
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of interleukin-1beta -induced NF-kappa B activation by calcium/calmodulin-dependent protein kinase kinase occurs through Akt activation associated with interleukin-1 receptor-associated kinase phosphorylation and uncoupling of MyD88.
    Chen BC; Wu WT; Ho FM; Lin WW
    J Biol Chem; 2002 Jul; 277(27):24169-79. PubMed ID: 11976320
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Heat-killed Brucella abortus induces TNF and IL-12p40 by distinct MyD88-dependent pathways: TNF, unlike IL-12p40 secretion, is Toll-like receptor 2 dependent.
    Huang LY; Aliberti J; Leifer CA; Segal DM; Sher A; Golenbock DT; Golding B
    J Immunol; 2003 Aug; 171(3):1441-6. PubMed ID: 12874236
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Toll-like receptor 4 and Toll-IL-1 receptor domain-containing adapter protein (TIRAP)/myeloid differentiation protein 88 adapter-like (Mal) contribute to maximal IL-6 expression in macrophages.
    Schilling D; Thomas K; Nixdorff K; Vogel SN; Fenton MJ
    J Immunol; 2002 Nov; 169(10):5874-80. PubMed ID: 12421970
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TLR signaling pathways.
    Takeda K; Akira S
    Semin Immunol; 2004 Feb; 16(1):3-9. PubMed ID: 14751757
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Intracellular bacterial infection-induced IFN-gamma is critically but not solely dependent on Toll-like receptor 4-myeloid differentiation factor 88-IFN-alpha beta-STAT1 signaling.
    Rothfuchs AG; Trumstedt C; Wigzell H; Rottenberg ME
    J Immunol; 2004 May; 172(10):6345-53. PubMed ID: 15128825
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.