162 related articles for article (PubMed ID: 12867484)
1. Identification of cytochrome p450 enzymes involved in the metabolism of 4'-methyl-alpha-pyrrolidinopropiophenone, a novel scheduled designer drug, in human liver microsomes.
Springer D; Paul LD; Staack RF; Kraemer T; Maurer HH
Drug Metab Dispos; 2003 Aug; 31(8):979-82. PubMed ID: 12867484
[TBL] [Abstract][Full Text] [Related]
2. Identification of human cytochrome P450 2D6 as major enzyme involved in the O-demethylation of the designer drug p-methoxymethamphetamine.
Staack RF; Theobald DS; Paul LD; Springer D; Kraemer T; Maurer HH
Drug Metab Dispos; 2004 Apr; 32(4):379-81. PubMed ID: 15039289
[TBL] [Abstract][Full Text] [Related]
3. Identification of cytochrome P450 enzymes involved in the metabolism of the new designer drug 4'-methyl-alpha-pyrrolidinobutyrophenone.
Peters FT; Meyer MR; Theobald DS; Maurer HH
Drug Metab Dispos; 2008 Jan; 36(1):163-8. PubMed ID: 17962373
[TBL] [Abstract][Full Text] [Related]
4. Identification of cytochrome P450 enzymes involved in the metabolism of 4'-methoxy-alpha-pyrrolidinopropiophenone (MOPPP), a designer drug, in human liver microsomes.
Springer D; Staack RF; Paul LD; Kraemer T; Maurer HH
Xenobiotica; 2003 Oct; 33(10):989-98. PubMed ID: 14555336
[TBL] [Abstract][Full Text] [Related]
5. Interaction of terfenadine and its primary metabolites with cytochrome P450 2D6.
Jones BC; Hyland R; Ackland M; Tyman CA; Smith DA
Drug Metab Dispos; 1998 Sep; 26(9):875-82. PubMed ID: 9733666
[TBL] [Abstract][Full Text] [Related]
6. Identification of cytochrome P450 enzymes involved in the metabolism of 3',4'-methylenedioxy-alpha-pyrrolidinopropiophenone (MDPPP), a designer drug, in human liver microsomes.
Springer D; Staack RF; Paul LD; Kraemer T; Maurer HH
Xenobiotica; 2005 Mar; 35(3):227-37. PubMed ID: 16019948
[TBL] [Abstract][Full Text] [Related]
7. CYP2D6 catalyzes tamoxifen 4-hydroxylation in human liver.
Dehal SS; Kupfer D
Cancer Res; 1997 Aug; 57(16):3402-6. PubMed ID: 9270005
[TBL] [Abstract][Full Text] [Related]
8. Characterization of human cytochrome P450 enzymes involved in the in vitro metabolism of perospirone.
Kitamura A; Mizuno Y; Natsui K; Yabuki M; Komuro S; Kanamaru H
Biopharm Drug Dispos; 2005 Mar; 26(2):59-65. PubMed ID: 15619261
[TBL] [Abstract][Full Text] [Related]
9. Functional characterization of human and cynomolgus monkey cytochrome P450 2E1 enzymes.
Hanioka N; Yamamoto M; Iwabu H; Jinno H; Tanaka-Kagawa T; Naito S; Shimizu T; Masuda K; Katsu T; Narimatsu S
Life Sci; 2007 Oct; 81(19-20):1436-45. PubMed ID: 17935737
[TBL] [Abstract][Full Text] [Related]
10. Cytochrome P450 dependent metabolism of the new designer drug 1-(3-trifluoromethylphenyl)piperazine (TFMPP). In vivo studies in Wistar and Dark Agouti rats as well as in vitro studies in human liver microsomes.
Staack RF; Paul LD; Springer D; Kraemer T; Maurer HH
Biochem Pharmacol; 2004 Jan; 67(2):235-44. PubMed ID: 14698036
[TBL] [Abstract][Full Text] [Related]
11. Identification of human cytochrome p450 isozymes involved in diphenhydramine N-demethylation.
Akutsu T; Kobayashi K; Sakurada K; Ikegaya H; Furihata T; Chiba K
Drug Metab Dispos; 2007 Jan; 35(1):72-8. PubMed ID: 17020955
[TBL] [Abstract][Full Text] [Related]
12. Biotransformation of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes.
Yao HT; Wu YS; Chang YW; Hsieh HP; Chen WC; Lan SJ; Chen CT; Chao YS; Chang L; Sun HY; Yeh TK
Drug Metab Dispos; 2007 Jul; 35(7):1042-9. PubMed ID: 17403915
[TBL] [Abstract][Full Text] [Related]
13. Cyp2D6 catalyzes 5-hydroxylation of 1-(2-pyrimidinyl)-piperazine, an active metabolite of several psychoactive drugs, in human liver microsomes.
Raghavan N; Zhang D; Zhu M; Zeng J; Christopher L
Drug Metab Dispos; 2005 Feb; 33(2):203-8. PubMed ID: 15507542
[TBL] [Abstract][Full Text] [Related]
14. Identification of cytochrome P450 enzymes involved in the metabolism of the designer drugs N-(1-phenylcyclohexyl)-3-ethoxypropanamine and N-(1-phenylcyclohexyl)-3-methoxypropanamine.
Sauer C; Peters FT; Schwaninger AE; Meyer MR; Maurer HH
Chem Res Toxicol; 2008 Oct; 21(10):1949-55. PubMed ID: 18778087
[TBL] [Abstract][Full Text] [Related]
15. 2,5-Dimethoxyamphetamine-derived designer drugs: studies on the identification of cytochrome P450 (CYP) isoenzymes involved in formation of their main metabolites and on their capability to inhibit CYP2D6.
Ewald AH; Maurer HH
Toxicol Lett; 2008 Dec; 183(1-3):52-7. PubMed ID: 18938231
[TBL] [Abstract][Full Text] [Related]
16. Kinetics of N- and C-hydroxylations of 2-acetylaminofluorene in male Sprague-Dawley rat liver microsomes: implications for carcinogenesis.
McManus ME; Minchin RF; Sanderson N; Wirth PJ; Thorgeirsson SS
Cancer Res; 1983 Aug; 43(8):3720-4. PubMed ID: 6861141
[TBL] [Abstract][Full Text] [Related]
17. A sensitive method for determination of cytochrome P4502D6 activity in vitro using bupranolol as substrate.
Appanna G; Tang BK; Mller R; Kalow W
Drug Metab Dispos; 1996 Mar; 24(3):303-6. PubMed ID: 8820420
[TBL] [Abstract][Full Text] [Related]
18. 3-ketocholanoic acid is the major in vitro human hepatic microsomal metabolite of lithocholic acid.
Deo AK; Bandiera SM
Drug Metab Dispos; 2009 Sep; 37(9):1938-47. PubMed ID: 19487251
[TBL] [Abstract][Full Text] [Related]
19. Characterization of the NADPH-dependent covalent binding of [14C]halothane to human liver microsomes: a role for cytochrome P4502E1 at low substrate concentrations.
Madan A; Parkinson A
Drug Metab Dispos; 1996 Dec; 24(12):1307-13. PubMed ID: 8971135
[TBL] [Abstract][Full Text] [Related]
20. Biotransformation of lithocholic acid by rat hepatic microsomes: metabolite analysis by liquid chromatography/mass spectrometry.
Deo AK; Bandiera SM
Drug Metab Dispos; 2008 Feb; 36(2):442-51. PubMed ID: 18039809
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
