78 related articles for article (PubMed ID: 12875239)
1. [Functional analysis of drug metabolizing enzymes using gene knockout animals].
Miyata M
Yakugaku Zasshi; 2003 Jul; 123(7):569-76. PubMed ID: 12875239
[TBL] [Abstract][Full Text] [Related]
2. Role for enhanced faecal excretion of bile acid in hydroxysteroid sulfotransferase-mediated protection against lithocholic acid-induced liver toxicity.
Miyata M; Watase H; Hori W; Shimada M; Nagata K; Gonzalez FJ; Yamazoe Y
Xenobiotica; 2006 Jul; 36(7):631-44. PubMed ID: 16864508
[TBL] [Abstract][Full Text] [Related]
3. Protective role of hydroxysteroid sulfotransferase in lithocholic acid-induced liver toxicity.
Kitada H; Miyata M; Nakamura T; Tozawa A; Honma W; Shimada M; Nagata K; Sinal CJ; Guo GL; Gonzalez FJ; Yamazoe Y
J Biol Chem; 2003 May; 278(20):17838-44. PubMed ID: 12637555
[TBL] [Abstract][Full Text] [Related]
4. Chenodeoxycholic acid-mediated activation of the farnesoid X receptor negatively regulates hydroxysteroid sulfotransferase.
Miyata M; Matsuda Y; Tsuchiya H; Kitada H; Akase T; Shimada M; Nagata K; Gonzalez FJ; Yamazoe Y
Drug Metab Pharmacokinet; 2006 Aug; 21(4):315-23. PubMed ID: 16946559
[TBL] [Abstract][Full Text] [Related]
5. Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene.
Miyata M; Kudo G; Lee YH; Yang TJ; Gelboin HV; Fernandez-Salguero P; Kimura S; Gonzalez FJ
J Biol Chem; 1999 Aug; 274(34):23963-8. PubMed ID: 10446164
[TBL] [Abstract][Full Text] [Related]
6. Relative importance of maternal and embryonic microsomal epoxide hydrolase in 7,12-dimethylbenz[a]anthracene-induced developmental toxicity.
Miyata M; Motoki K; Tamura E; Furukawa M; Gonzalez FJ; Yamazoe Y
Biochem Pharmacol; 2002 Mar; 63(6):1077-84. PubMed ID: 11931840
[TBL] [Abstract][Full Text] [Related]
7. Microsomal expoxide hydrolase is required for 7,12-dimethylbenz[a]anthracene (DMBA)-induced immunotoxicity in mice.
Gao J; Lauer FT; Mitchell LA; Burchiel SW
Toxicol Sci; 2007 Jul; 98(1):137-44. PubMed ID: 17442664
[TBL] [Abstract][Full Text] [Related]
8. Role of farnesoid X receptor in the enhancement of canalicular bile acid output and excretion of unconjugated bile acids: a mechanism for protection against cholic acid-induced liver toxicity.
Miyata M; Tozawa A; Otsuka H; Nakamura T; Nagata K; Gonzalez FJ; Yamazoe Y
J Pharmacol Exp Ther; 2005 Feb; 312(2):759-66. PubMed ID: 15466244
[TBL] [Abstract][Full Text] [Related]
9. Mechanism of 7,12-dimethylbenz[a]anthracene-induced immunotoxicity: role of metabolic activation at the target organ.
Miyata M; Furukawa M; Takahashi K; Gonzalez FJ; Yamazoe Y
Jpn J Pharmacol; 2001 Jul; 86(3):302-9. PubMed ID: 11488430
[TBL] [Abstract][Full Text] [Related]
10. Regulation of drug transporters by the farnesoid X receptor in mice.
Maeda T; Miyata M; Yotsumoto T; Kobayashi D; Nozawa T; Toyama K; Gonzalez FJ; Yamazoe Y; Tamai I
Mol Pharm; 2004; 1(4):281-9. PubMed ID: 15981587
[TBL] [Abstract][Full Text] [Related]
11. ME3738 protects against lithocholic acid-induced hepatotoxicity, which is associated with enhancement of biliary bile acid and cholesterol output.
Nomoto M; Miyata M; Shimada M; Yoshinari K; Gonzalez FJ; Shibasaki S; Kurosawa T; Shindo Y; Yamazoe Y
Eur J Pharmacol; 2007 Nov; 574(2-3):192-200. PubMed ID: 17651726
[TBL] [Abstract][Full Text] [Related]
12. Bile acid-induced elevated oxidative stress in the absence of farnesoid X receptor.
Nomoto M; Miyata M; Yin S; Kurata Y; Shimada M; Yoshinari K; Gonzalez FJ; Suzuki K; Shibasaki S; Kurosawa T; Yamazoe Y
Biol Pharm Bull; 2009 Feb; 32(2):172-8. PubMed ID: 19182371
[TBL] [Abstract][Full Text] [Related]
13. Targeted disruption of soluble epoxide hydrolase reveals a role in blood pressure regulation.
Sinal CJ; Miyata M; Tohkin M; Nagata K; Bend JR; Gonzalez FJ
J Biol Chem; 2000 Dec; 275(51):40504-10. PubMed ID: 11001943
[TBL] [Abstract][Full Text] [Related]
14. p53 and ATM/ATR regulate 7,12-dimethylbenz[a]anthracene-induced immunosuppression.
Gao J; Mitchell LA; Lauer FT; Burchiel SW
Mol Pharmacol; 2008 Jan; 73(1):137-46. PubMed ID: 17925458
[TBL] [Abstract][Full Text] [Related]
15. Constitutive androstane receptor-mediated changes in bile acid composition contributes to hepatoprotection from lithocholic acid-induced liver injury in mice.
Beilke LD; Aleksunes LM; Holland RD; Besselsen DG; Beger RD; Klaassen CD; Cherrington NJ
Drug Metab Dispos; 2009 May; 37(5):1035-45. PubMed ID: 19196849
[TBL] [Abstract][Full Text] [Related]
16. Beyond detoxification: a role for mouse mEH in the hepatic metabolism of endogenous lipids.
Marowsky A; Meyer I; Erismann-Ebner K; Pellegrini G; Mule N; Arand M
Arch Toxicol; 2017 Nov; 91(11):3571-3585. PubMed ID: 28975360
[TBL] [Abstract][Full Text] [Related]
17. Protective effects of yangonin from an edible botanical Kava against lithocholic acid-induced cholestasis and hepatotoxicity.
Kong Y; Gao X; Wang C; Ning C; Liu K; Liu Z; Sun H; Ma X; Sun P; Meng Q
Eur J Pharmacol; 2018 Apr; 824():64-71. PubMed ID: 29427579
[TBL] [Abstract][Full Text] [Related]
18. involvement of microsomal epoxide hydrolase enzyme in ovotoxicity caused by 7,12-dimethylbenz[a]anthracene.
Rajapaksa KS; Sipes IG; Hoyer PB
Toxicol Sci; 2007 Apr; 96(2):327-34. PubMed ID: 17204581
[TBL] [Abstract][Full Text] [Related]
19. Farnesoid X-activated receptor induces apolipoprotein C-II transcription: a molecular mechanism linking plasma triglyceride levels to bile acids.
Kast HR; Nguyen CM; Sinal CJ; Jones SA; Laffitte BA; Reue K; Gonzalez FJ; Willson TM; Edwards PA
Mol Endocrinol; 2001 Oct; 15(10):1720-8. PubMed ID: 11579204
[TBL] [Abstract][Full Text] [Related]
20. Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice.
Wagner M; Fickert P; Zollner G; Fuchsbichler A; Silbert D; Tsybrovskyy O; Zatloukal K; Guo GL; Schuetz JD; Gonzalez FJ; Marschall HU; Denk H; Trauner M
Gastroenterology; 2003 Sep; 125(3):825-38. PubMed ID: 12949728
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]