BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

906 related articles for article (PubMed ID: 12876289)

  • 21. Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta.
    Feng XH; Lin X; Derynck R
    EMBO J; 2000 Oct; 19(19):5178-93. PubMed ID: 11013220
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Activations of ERK1/2 and JNK by transforming growth factor beta negatively regulate Smad3-induced alkaline phosphatase activity and mineralization in mouse osteoblastic cells.
    Sowa H; Kaji H; Yamaguchi T; Sugimoto T; Chihara K
    J Biol Chem; 2002 Sep; 277(39):36024-31. PubMed ID: 12130649
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Inhibition of phosphatidylinositol 3-kinase-Akt signaling blocks growth, promotes apoptosis, and enhances sensitivity of small cell lung cancer cells to chemotherapy.
    Krystal GW; Sulanke G; Litz J
    Mol Cancer Ther; 2002 Sep; 1(11):913-22. PubMed ID: 12481412
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Akt interacts directly with Smad3 to regulate the sensitivity to TGF-beta induced apoptosis.
    Conery AR; Cao Y; Thompson EA; Townsend CM; Ko TC; Luo K
    Nat Cell Biol; 2004 Apr; 6(4):366-72. PubMed ID: 15104092
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts.
    Piek E; Ju WJ; Heyer J; Escalante-Alcalde D; Stewart CL; Weinstein M; Deng C; Kucherlapati R; Bottinger EP; Roberts AB
    J Biol Chem; 2001 Jun; 276(23):19945-53. PubMed ID: 11262418
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Requirement of BMP-2-induced phosphatidylinositol 3-kinase and Akt serine/threonine kinase in osteoblast differentiation and Smad-dependent BMP-2 gene transcription.
    Ghosh-Choudhury N; Abboud SL; Nishimura R; Celeste A; Mahimainathan L; Choudhury GG
    J Biol Chem; 2002 Sep; 277(36):33361-8. PubMed ID: 12084724
    [TBL] [Abstract][Full Text] [Related]  

  • 27. PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway.
    Weng LP; Brown JL; Baker KM; Ostrowski MC; Eng C
    Hum Mol Genet; 2002 Jul; 11(15):1687-96. PubMed ID: 12095911
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling.
    Zhang D; Brodt P
    Oncogene; 2003 Feb; 22(7):974-82. PubMed ID: 12592384
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Requirement of Ras/MAPK pathway activation by transforming growth factor beta for transforming growth factor beta 1 production in a Smad-dependent pathway.
    Yue J; Mulder KM
    J Biol Chem; 2000 Oct; 275(40):30765-73. PubMed ID: 10843986
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3.
    Yuan W; Varga J
    J Biol Chem; 2001 Oct; 276(42):38502-10. PubMed ID: 11502752
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate-1/phosphatidylinositol 3-kinase cascade.
    Shi Y; Yan H; Frost P; Gera J; Lichtenstein A
    Mol Cancer Ther; 2005 Oct; 4(10):1533-40. PubMed ID: 16227402
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Growth differentiation factor-9 signaling is mediated by the type I receptor, activin receptor-like kinase 5.
    Mazerbourg S; Klein C; Roh J; Kaivo-Oja N; Mottershead DG; Korchynskyi O; Ritvos O; Hsueh AJ
    Mol Endocrinol; 2004 Mar; 18(3):653-65. PubMed ID: 14684852
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The functional interaction between the paired domain transcription factor Pax8 and Smad3 is involved in transforming growth factor-beta repression of the sodium/iodide symporter gene.
    Costamagna E; GarcĂ­a B; Santisteban P
    J Biol Chem; 2004 Jan; 279(5):3439-46. PubMed ID: 14623893
    [TBL] [Abstract][Full Text] [Related]  

  • 34. TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4.
    Nakao A; Imamura T; Souchelnytskyi S; Kawabata M; Ishisaki A; Oeda E; Tamaki K; Hanai J; Heldin CH; Miyazono K; ten Dijke P
    EMBO J; 1997 Sep; 16(17):5353-62. PubMed ID: 9311995
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mitogenic conversion of transforming growth factor-beta1 effect by oncogenic Ha-Ras-induced activation of the mitogen-activated protein kinase signaling pathway in human prostate cancer.
    Park BJ; Park JI; Byun DS; Park JH; Chi SG
    Cancer Res; 2000 Jun; 60(11):3031-8. PubMed ID: 10850453
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Regulation of Fas expression by STAT3 and c-Jun is mediated by phosphatidylinositol 3-kinase-AKT signaling.
    Ivanov VN; Krasilnikov M; Ronai Z
    J Biol Chem; 2002 Feb; 277(7):4932-44. PubMed ID: 11733515
    [TBL] [Abstract][Full Text] [Related]  

  • 37. NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
    Kuratomi G; Komuro A; Goto K; Shinozaki M; Miyazawa K; Miyazono K; Imamura T
    Biochem J; 2005 Mar; 386(Pt 3):461-70. PubMed ID: 15496141
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The transcriptional co-activator P/CAF potentiates TGF-beta/Smad signaling.
    Itoh S; Ericsson J; Nishikawa J; Heldin CH; ten Dijke P
    Nucleic Acids Res; 2000 Nov; 28(21):4291-8. PubMed ID: 11058129
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Activin receptor-like kinase-7 induces apoptosis through activation of MAPKs in a Smad3-dependent mechanism in hepatoma cells.
    Kim BC; van Gelder H; Kim TA; Lee HJ; Baik KG; Chun HH; Lee DA; Choi KS; Kim SJ
    J Biol Chem; 2004 Jul; 279(27):28458-65. PubMed ID: 15107418
    [TBL] [Abstract][Full Text] [Related]  

  • 40. PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3.
    Remy I; Montmarquette A; Michnick SW
    Nat Cell Biol; 2004 Apr; 6(4):358-65. PubMed ID: 15048128
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 46.