These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 12879020)

  • 1. Regulation of the Wnt signalling component PAR1A by the Peutz-Jeghers syndrome kinase LKB1.
    Spicer J; Rayter S; Young N; Elliott R; Ashworth A; Smith D
    Oncogene; 2003 Jul; 22(30):4752-6. PubMed ID: 12879020
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Peutz-Jeghers LKB1 mutants fail to activate GSK-3beta, preventing it from inhibiting Wnt signaling.
    Lin-Marq N; Borel C; Antonarakis SE
    Mol Genet Genomics; 2005 Apr; 273(2):184-96. PubMed ID: 15731909
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LKB1 (XEEK1) regulates Wnt signalling in vertebrate development.
    Ossipova O; Bardeesy N; DePinho RA; Green JB
    Nat Cell Biol; 2003 Oct; 5(10):889-94. PubMed ID: 12973359
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression.
    Ma Y; Zhang G; Fu X; Xia O; Zhan C; Li L; Wang Z; Wu B
    Oncol Rep; 2010 Jun; 23(6):1569-76. PubMed ID: 20428811
    [TBL] [Abstract][Full Text] [Related]  

  • 5. LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1.
    Smith DP; Rayter SI; Niederlander C; Spicer J; Jones CM; Ashworth A
    Hum Mol Genet; 2001 Dec; 10(25):2869-77. PubMed ID: 11741830
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome.
    Sapkota GP; Boudeau J; Deak M; Kieloch A; Morrice N; Alessi DR
    Biochem J; 2002 Mar; 362(Pt 2):481-90. PubMed ID: 11853558
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Analysis of the LKB1-STRAD-MO25 complex.
    Boudeau J; Scott JW; Resta N; Deak M; Kieloch A; Komander D; Hardie DG; Prescott AR; van Aalten DM; Alessi DR
    J Cell Sci; 2004 Dec; 117(Pt 26):6365-75. PubMed ID: 15561763
    [TBL] [Abstract][Full Text] [Related]  

  • 8. LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo.
    Collins SP; Reoma JL; Gamm DM; Uhler MD
    Biochem J; 2000 Feb; 345 Pt 3(Pt 3):673-80. PubMed ID: 10642527
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Utilization of liquid chromatography mass spectrometry analyses to identify LKB1-APC interaction in modulating Wnt/β-catenin pathway of lung cancer cells.
    Jian SF; Hsiao CC; Chen SY; Weng CC; Kuo TL; Wu DC; Hung WC; Cheng KH
    Mol Cancer Res; 2014 Apr; 12(4):622-35. PubMed ID: 24448687
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Elevation of WNT5A expression in polyp formation in Lkb1+/- mice and Peutz-Jeghers syndrome.
    Lai C; Robinson J; Clark S; Stamp G; Poulsom R; Silver A
    J Pathol; 2011 Apr; 223(5):584-92. PubMed ID: 21341271
    [TBL] [Abstract][Full Text] [Related]  

  • 11. LKB1, a protein kinase regulating cell proliferation and polarity.
    Boudeau J; Sapkota G; Alessi DR
    FEBS Lett; 2003 Jul; 546(1):159-65. PubMed ID: 12829253
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth.
    Sapkota GP; Kieloch A; Lizcano JM; Lain S; Arthur JS; Williams MR; Morrice N; Deak M; Alessi DR
    J Biol Chem; 2001 Jun; 276(22):19469-82. PubMed ID: 11297520
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Loss of cytoplasmic retention ability of mutant LKB1 found in Peutz-Jeghers syndrome patients.
    Nezu J; Oku A; Shimane M
    Biochem Biophys Res Commun; 1999 Aug; 261(3):750-5. PubMed ID: 10441497
    [TBL] [Abstract][Full Text] [Related]  

  • 14. mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome.
    Shackelford DB; Vasquez DS; Corbeil J; Wu S; Leblanc M; Wu CL; Vera DR; Shaw RJ
    Proc Natl Acad Sci U S A; 2009 Jul; 106(27):11137-42. PubMed ID: 19541609
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneity.
    Mehenni H; Gehrig C; Nezu J; Oku A; Shimane M; Rossier C; Guex N; Blouin JL; Scott HS; Antonarakis SE
    Am J Hum Genet; 1998 Dec; 63(6):1641-50. PubMed ID: 9837816
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome.
    Corradetti MN; Inoki K; Bardeesy N; DePinho RA; Guan KL
    Genes Dev; 2004 Jul; 18(13):1533-8. PubMed ID: 15231735
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of a novel mRNA species of the LKB1/STK11 Peutz-Jeghers serine/threonine kinase.
    Churchman M; Dowling B; Tomlinson IP
    DNA Seq; 1999; 10(4-5):255-61. PubMed ID: 10727082
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional analysis of LKB1/STK11 mutants and two aberrant isoforms found in Peutz-Jeghers Syndrome patients.
    Boudeau J; Kieloch A; Alessi DR; Stella A; Guanti G; Resta N
    Hum Mutat; 2003 Feb; 21(2):172. PubMed ID: 12552571
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A serine/threonine kinase gene defective in Peutz-Jeghers syndrome.
    Hemminki A; Markie D; Tomlinson I; Avizienyte E; Roth S; Loukola A; Bignell G; Warren W; Aminoff M; Höglund P; Järvinen H; Kristo P; Pelin K; Ridanpää M; Salovaara R; Toro T; Bodmer W; Olschwang S; Olsen AS; Stratton MR; de la Chapelle A; Aaltonen LA
    Nature; 1998 Jan; 391(6663):184-7. PubMed ID: 9428765
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Wnt signalling gets XEEKy.
    Clements WK; Kimelman D
    Nat Cell Biol; 2003 Oct; 5(10):861-3. PubMed ID: 14523399
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 9.