176 related articles for article (PubMed ID: 12881525)
1. Inhibition of Werner syndrome helicase activity by benzo[c]phenanthrene diol epoxide dA adducts in DNA is both strand-and stereoisomer-dependent.
Driscoll HC; Matson SW; Sayer JM; Kroth H; Jerina DM; Brosh RM
J Biol Chem; 2003 Oct; 278(42):41126-35. PubMed ID: 12881525
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of Werner syndrome helicase activity by benzo[a]pyrene diol epoxide adducts can be overcome by replication protein A.
Choudhary S; Doherty KM; Handy CJ; Sayer JM; Yagi H; Jerina DM; Brosh RM
J Biol Chem; 2006 Mar; 281(9):6000-9. PubMed ID: 16380375
[TBL] [Abstract][Full Text] [Related]
3. Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteins.
Machwe A; Lozada EM; Xiao L; Orren DK
BMC Mol Biol; 2006 Jan; 7():1. PubMed ID: 16412221
[TBL] [Abstract][Full Text] [Related]
4. Biochemical and kinetic characterization of the DNA helicase and exonuclease activities of werner syndrome protein.
Choudhary S; Sommers JA; Brosh RM
J Biol Chem; 2004 Aug; 279(33):34603-13. PubMed ID: 15187093
[TBL] [Abstract][Full Text] [Related]
5. Marked differences in base selectivity between DNA and the free nucleotides upon adduct formation from Bay- and Fjord-region diol epoxides.
Vepachedu SR; Ya N; Yagi H; Sayer JM; Jerina DM
Chem Res Toxicol; 2000 Sep; 13(9):883-90. PubMed ID: 10995261
[TBL] [Abstract][Full Text] [Related]
6. Stereochemical specificity in the metabolic activation of benzo(c)phenanthrene to metabolites that covalently bind to DNA in rodent embryo cell cultures.
Pruess-Schwartz D; Baird WM; Yagi H; Jerina DM; Pigott MA; Dipple A
Cancer Res; 1987 Aug; 47(15):4032-7. PubMed ID: 3607748
[TBL] [Abstract][Full Text] [Related]
7. RecQ family members combine strand pairing and unwinding activities to catalyze strand exchange.
Machwe A; Xiao L; Groden J; Matson SW; Orren DK
J Biol Chem; 2005 Jun; 280(24):23397-407. PubMed ID: 15845538
[TBL] [Abstract][Full Text] [Related]
8. Physical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicases.
Doherty KM; Sommers JA; Gray MD; Lee JW; von Kobbe C; Thoma NH; Kureekattil RP; Kenny MK; Brosh RM
J Biol Chem; 2005 Aug; 280(33):29494-505. PubMed ID: 15965237
[TBL] [Abstract][Full Text] [Related]
9. Enzymatic mechanism of the WRN helicase/nuclease.
Brosh RM; Opresko PL; Bohr VA
Methods Enzymol; 2006; 409():52-85. PubMed ID: 16793395
[TBL] [Abstract][Full Text] [Related]
10. POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates.
Opresko PL; Mason PA; Podell ER; Lei M; Hickson ID; Cech TR; Bohr VA
J Biol Chem; 2005 Sep; 280(37):32069-80. PubMed ID: 16030011
[TBL] [Abstract][Full Text] [Related]
11. Patterns of resistance to exonuclease digestion of oligonucleotides containing polycyclic aromatic hydrocarbon diol epoxide adducts at N6 of deoxyadenosine.
Ilankumaran P; Pannell LK; Gebreselassie P; Pilcher AS; Yagi H; Sayer JM; Jerina DM
Chem Res Toxicol; 2001 Sep; 14(9):1330-8. PubMed ID: 11559050
[TBL] [Abstract][Full Text] [Related]
12. Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A.
Shen JC; Gray MD; Oshima J; Loeb LA
Nucleic Acids Res; 1998 Jun; 26(12):2879-85. PubMed ID: 9611231
[TBL] [Abstract][Full Text] [Related]
13. RPA alleviates the inhibitory effect of vinylphosphonate internucleotide linkages on DNA unwinding by BLM and WRN helicases.
Garcia PL; Bradley G; Hayes CJ; Krintel S; Soultanas P; Janscak P
Nucleic Acids Res; 2004; 32(12):3771-8. PubMed ID: 15256542
[TBL] [Abstract][Full Text] [Related]
14. Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity.
Lin CH; Huang X; Kolbanovskii A; Hingerty BE; Amin S; Broyde S; Geacintov NE; Patel DJ
J Mol Biol; 2001 Mar; 306(5):1059-80. PubMed ID: 11237618
[TBL] [Abstract][Full Text] [Related]
15. Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein.
Opresko PL; Laine JP; Brosh RM; Seidman MM; Bohr VA
J Biol Chem; 2001 Nov; 276(48):44677-87. PubMed ID: 11572872
[TBL] [Abstract][Full Text] [Related]
16. Sequence context effects on mutational properties of cis-opened benzo[c]phenanthrene diol epoxide-deoxyadenosine adducts in site-specific mutation studies.
Pontén I; Sayer JM; Pilcher AS; Yagi H; Kumar S; Jerina DM; Dipple A
Biochemistry; 1999 Jan; 38(3):1144-52. PubMed ID: 9894012
[TBL] [Abstract][Full Text] [Related]
17. Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide.
Garcia PL; Liu Y; Jiricny J; West SC; Janscak P
EMBO J; 2004 Jul; 23(14):2882-91. PubMed ID: 15241474
[TBL] [Abstract][Full Text] [Related]
18. Potent inhibition of werner and bloom helicases by DNA minor groove binding drugs.
Brosh RM; Karow JK; White EJ; Shaw ND; Hickson ID; Bohr VA
Nucleic Acids Res; 2000 Jun; 28(12):2420-30. PubMed ID: 10871376
[TBL] [Abstract][Full Text] [Related]
19. p53 modulates RPA-dependent and RPA-independent WRN helicase activity.
Sommers JA; Sharma S; Doherty KM; Karmakar P; Yang Q; Kenny MK; Harris CC; Brosh RM
Cancer Res; 2005 Feb; 65(4):1223-33. PubMed ID: 15735006
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress.
Aggarwal M; Sommers JA; Shoemaker RH; Brosh RM
Proc Natl Acad Sci U S A; 2011 Jan; 108(4):1525-30. PubMed ID: 21220316
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
