These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

67 related articles for article (PubMed ID: 12881708)

  • 1. The proline-rich region of mouse p53 influences transactivation and apoptosis but is largely dispensable for these functions.
    Edwards SJ; Hananeia L; Eccles MR; Zhang YF; Braithwaite AW
    Oncogene; 2003 Jul; 22(29):4517-23. PubMed ID: 12881708
    [TBL] [Abstract][Full Text] [Related]  

  • 2. p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements.
    Campomenosi P; Monti P; Aprile A; Abbondandolo A; Frebourg T; Gold B; Crook T; Inga A; Resnick MA; Iggo R; Fronza G
    Oncogene; 2001 Jun; 20(27):3573-9. PubMed ID: 11429705
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool.
    Luo JL; Yang Q; Tong WM; Hergenhahn M; Wang ZQ; Hollstein M
    Oncogene; 2001 Jan; 20(3):320-8. PubMed ID: 11313961
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Apoptosis. p53 and PUMA: a deadly duo.
    Vousden KH
    Science; 2005 Sep; 309(5741):1685-6. PubMed ID: 16151000
    [No Abstract]   [Full Text] [Related]  

  • 5. Differential regulation of cellular target genes by p53 devoid of the PXXP motifs with impaired apoptotic activity.
    Zhu J; Jiang J; Zhou W; Zhu K; Chen X
    Oncogene; 1999 Mar; 18(12):2149-55. PubMed ID: 10321740
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gamma interferon-inducible protein 10 induces HeLa cell apoptosis through a p53-dependent pathway initiated by suppression of human papillomavirus type 18 E6 and E7 expression.
    Zhang HM; Yuan J; Cheung P; Chau D; Wong BW; McManus BM; Yang D
    Mol Cell Biol; 2005 Jul; 25(14):6247-58. PubMed ID: 15988033
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BRCA1 physically associates with p53 and stimulates its transcriptional activity.
    Zhang H; Somasundaram K; Peng Y; Tian H; Zhang H; Bi D; Weber BL; El-Deiry WS
    Oncogene; 1998 Apr; 16(13):1713-21. PubMed ID: 9582019
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis.
    Chipuk JE; Kuwana T; Bouchier-Hayes L; Droin NM; Newmeyer DD; Schuler M; Green DR
    Science; 2004 Feb; 303(5660):1010-4. PubMed ID: 14963330
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The 7-amino-acid site in the proline-rich region of the N-terminal domain of p53 is involved in the interaction with FAK and is critical for p53 functioning.
    Golubovskaya VM; Finch R; Zheng M; Kurenova EV; Cance WG
    Biochem J; 2008 Apr; 411(1):151-60. PubMed ID: 18215142
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression.
    Venot C; Maratrat M; Dureuil C; Conseiller E; Bracco L; Debussche L
    EMBO J; 1998 Aug; 17(16):4668-79. PubMed ID: 9707426
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Physical and functional interactions between members of the tumour suppressor p53 and the Sp families of transcription factors: importance for the regulation of genes involved in cell-cycle arrest and apoptosis.
    Koutsodontis G; Vasilaki E; Chou WC; Papakosta P; Kardassis D
    Biochem J; 2005 Jul; 389(Pt 2):443-55. PubMed ID: 15790310
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Integral role of Noxa in p53-mediated apoptotic response.
    Shibue T; Takeda K; Oda E; Tanaka H; Murasawa H; Takaoka A; Morishita Y; Akira S; Taniguchi T; Tanaka N
    Genes Dev; 2003 Sep; 17(18):2233-8. PubMed ID: 12952892
    [TBL] [Abstract][Full Text] [Related]  

  • 13. p53 transcription-dependent and -independent regulation of cerebellar neural precursor cell apoptosis.
    Geng Y; Akhtar RS; Shacka JJ; Klocke BJ; Zhang J; Chen X; Roth KA
    J Neuropathol Exp Neurol; 2007 Jan; 66(1):66-74. PubMed ID: 17204938
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RB18A, whose gene is localized on chromosome 17q12-q21.1, regulates in vivo p53 transactivating activity.
    Frade R; Balbo M; Barel M
    Cancer Res; 2000 Dec; 60(23):6585-9. PubMed ID: 11118038
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PUMA couples the nuclear and cytoplasmic proapoptotic function of p53.
    Chipuk JE; Bouchier-Hayes L; Kuwana T; Newmeyer DD; Green DR
    Science; 2005 Sep; 309(5741):1732-5. PubMed ID: 16151013
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Both p53-PUMA/NOXA-Bax-mitochondrion and p53-p21cip1 pathways are involved in the CDglyTK-mediated tumor cell suppression.
    Yu Z; Wang H; Zhang L; Tang A; Zhai Q; Wen J; Yao L; Li P
    Biochem Biophys Res Commun; 2009 Sep; 386(4):607-11. PubMed ID: 19540190
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.
    Unger T; Sionov RV; Moallem E; Yee CL; Howley PM; Oren M; Haupt Y
    Oncogene; 1999 May; 18(21):3205-12. PubMed ID: 10359526
    [TBL] [Abstract][Full Text] [Related]  

  • 18. LKB1 is recruited to the p21/WAF1 promoter by p53 to mediate transcriptional activation.
    Zeng PY; Berger SL
    Cancer Res; 2006 Nov; 66(22):10701-8. PubMed ID: 17108107
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ionizing radiation induces a p53-dependent apoptotic mechanism in ARPE-19 cells.
    Jiang YL; Escaño MF; Sasaki R; Fujii S; Kusuhara S; Matsumoto A; Sugimura K; Negi A
    Jpn J Ophthalmol; 2004; 48(2):106-14. PubMed ID: 15064971
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Puma(*)Mcl-1 interaction is not sufficient to prevent rapid degradation of Mcl-1.
    Mei Y; Du W; Yang Y; Wu M
    Oncogene; 2005 Nov; 24(48):7224-37. PubMed ID: 16007132
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.