BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

121 related articles for article (PubMed ID: 12885157)

  • 1. Involvement of GANP in B cell activation in T cell-dependent antigen response.
    Sakaguchi N; Fujimura S; Kuwahara K
    Dev Immunol; 2002 Sep; 9(3):169-72. PubMed ID: 12885157
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Germinal center-associated nuclear protein (GANP) has a phosphorylation-dependent DNA-primase activity that is up-regulated in germinal center regions.
    Kuwahara K; Tomiyasu S; Fujimura S; Nomura K; Xing Y; Nishiyama N; Ogawa M; Imajoh-Ohmi S; Izuta S; Sakaguchi N
    Proc Natl Acad Sci U S A; 2001 Aug; 98(18):10279-83. PubMed ID: 11526238
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel nuclear phosphoprotein, GANP, is up-regulated in centrocytes of the germinal center and associated with MCM3, a protein essential for DNA replication.
    Kuwahara K; Yoshida M; Kondo E; Sakata A; Watanabe Y; Abe E; Kouno Y; Tomiyasu S; Fujimura S; Tokuhisa T; Kimura H; Ezaki T; Sakaguchi N
    Blood; 2000 Apr; 95(7):2321-8. PubMed ID: 10733502
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular mechanism of immunoglobulin V-region diversification regulated by transcription and RNA metabolism in antigen-driven B cells.
    Sakaguchi N; Maeda K; Kuwahara K
    Scand J Immunol; 2011 Jun; 73(6):520-6. PubMed ID: 21388430
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Germinal Center B-Cell-Associated Nuclear Protein (GANP) Involved in RNA Metabolism for B Cell Maturation.
    Sakaguchi N; Maeda K
    Adv Immunol; 2016; 131():135-86. PubMed ID: 27235683
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Spontaneous increase of plasma-like cells with high GANP expression in the extrafollicular region of lymphoid organs of autoimmune-prone mice.
    Fujimura S; Kuwahara K; Ezaki T; Tomita K; Hirose S; Sakaguchi N
    J Autoimmun; 2003 Jun; 20(4):291-301. PubMed ID: 12791315
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure, expression, and chromosomal localization of the human gene encoding a germinal center-associated nuclear protein (GANP) that associates with MCM3 involved in the initiation of DNA replication.
    Abe E; Kuwahara K; Yoshida M; Suzuki M; Terasaki H; Matsuo Y; Takahashi EI; Sakaguchi N
    Gene; 2000 Sep; 255(2):219-27. PubMed ID: 11024281
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Role of GANP in B cell activation].
    Kuwahara K; Sakaguchi N
    Tanpakushitsu Kakusan Koso; 2002 Dec; 47(16 Suppl):2300-5. PubMed ID: 12518452
    [No Abstract]   [Full Text] [Related]  

  • 9. Germinal center-associated nuclear protein contributes to affinity maturation of B cell antigen receptor in T cell-dependent responses.
    Kuwahara K; Fujimura S; Takahashi Y; Nakagata N; Takemori T; Aizawa S; Sakaguchi N
    Proc Natl Acad Sci U S A; 2004 Jan; 101(4):1010-5. PubMed ID: 14715907
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Generation of high-affinity antibody against T cell-dependent antigen in the Ganp gene-transgenic mouse.
    Sakaguchi N; Kimura T; Matsushita S; Fujimura S; Shibata J; Araki M; Sakamoto T; Minoda C; Kuwahara K
    J Immunol; 2005 Apr; 174(8):4485-94. PubMed ID: 15814669
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PU.1 is involved in the regulation of B lineage-associated and developmental stage-dependent expression of the germinal center-associated DNA primase GANP.
    EL-Gazzar MA; Maeda K; Nomiyama H; Nakao M; Kuwahara K; Sakaguchi N
    J Biol Chem; 2001 Dec; 276(51):48000-8. PubMed ID: 11641399
    [TBL] [Abstract][Full Text] [Related]  

  • 12. GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy.
    Singh SK; Maeda K; Eid MM; Almofty SA; Ono M; Pham P; Goodman MF; Sakaguchi N
    Nat Commun; 2013; 4():1830. PubMed ID: 23652018
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA.
    Maeda K; Singh SK; Eda K; Kitabatake M; Pham P; Goodman MF; Sakaguchi N
    J Biol Chem; 2010 Jul; 285(31):23945-53. PubMed ID: 20507984
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GANP suppresses the arginine methyltransferase PRMT5 regulating IL-4-mediated STAT6-signaling to IgE production in B cells.
    Igarashi H; Kuwahara K; Yoshida M; Xing Y; Maeda K; Nakajima K; Sakaguchi N
    Mol Immunol; 2009 Mar; 46(6):1031-41. PubMed ID: 19181385
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cutting edge: double-stranded DNA breaks in the IgV region gene were detected at lower frequency in affinity-maturation impeded GANP-/- mice.
    Kawatani Y; Igarashi H; Matsui T; Kuwahara K; Fujimura S; Okamoto N; Takagi K; Sakaguchi N
    J Immunol; 2005 Nov; 175(9):5615-8. PubMed ID: 16237049
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MCM3-binding GANP DNA-primase is associated with a novel phosphatase component G5PR.
    Kono Y; Maeda K; Kuwahara K; Yamamoto H; Miyamoto E; Yonezawa K; Takagi K; Sakaguchi N
    Genes Cells; 2002 Aug; 7(8):821-34. PubMed ID: 12167160
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lyn signaling to upregulate GANP is critical for the survival of high-affinity B cells in germinal centers of lymphoid organs.
    Kuwahara K; Nakaya T; Phimsen S; Toda T; Kitabatake M; Kaji T; Takemori T; Watanabe T; Sakaguchi N
    J Immunol; 2012 Oct; 189(7):3472-9. PubMed ID: 22942428
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of Blimp-1 in the GC reaction: differential expression of Blimp-1 upon immunization with TD and TI antigens.
    Lindroth K; Fernández C
    Immunol Lett; 2007 Nov; 113(2):70-5. PubMed ID: 17850884
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Toll-like receptor 4 signaling by follicular dendritic cells is pivotal for germinal center onset and affinity maturation.
    Garin A; Meyer-Hermann M; Contie M; Figge MT; Buatois V; Gunzer M; Toellner KM; Elson G; Kosco-Vilbois MH
    Immunity; 2010 Jul; 33(1):84-95. PubMed ID: 20643339
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Integrity of immunoglobulin variable regions is supported by GANP during AID-induced somatic hypermutation in germinal center B cells.
    Eid MMA; Shimoda M; Singh SK; Almofty SA; Pham P; Goodman MF; Maeda K; Sakaguchi N
    Int Immunol; 2017 May; 29(5):211-220. PubMed ID: 28541550
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.