These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
183 related articles for article (PubMed ID: 12889164)
1. [Secretases as targets for the treatment of Alzheimer's disease]. Luo HM; Gu F Sheng Li Ke Xue Jin Zhan; 2003 Apr; 34(2):189-92. PubMed ID: 12889164 [No Abstract] [Full Text] [Related]
2. Alzheimer's disease. Closing in on gamma-secretase. De Strooper B Nature; 2000 Jun; 405(6787):627, 629. PubMed ID: 10864307 [No Abstract] [Full Text] [Related]
3. Specific enzyme identified that snips APP into beta-amyloid. Senior K Drug Discov Today; 2005 Nov; 10(21):1408. PubMed ID: 16243255 [No Abstract] [Full Text] [Related]
4. [The complex enzymic process yielding beta-amyloid protein in Alzheimer's disease]. Sela B Harefuah; 2000 Jul; 139(1-2):42-7. PubMed ID: 10979452 [No Abstract] [Full Text] [Related]
5. Alzheimer's disease. A firm base for drug development. De Strooper B; König G Nature; 1999 Dec; 402(6761):471-2. PubMed ID: 10591201 [No Abstract] [Full Text] [Related]
7. Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation. Luo Y; Bolon B; Kahn S; Bennett BD; Babu-Khan S; Denis P; Fan W; Kha H; Zhang J; Gong Y; Martin L; Louis JC; Yan Q; Richards WG; Citron M; Vassar R Nat Neurosci; 2001 Mar; 4(3):231-2. PubMed ID: 11224535 [No Abstract] [Full Text] [Related]
8. A substrate-based difluoro ketone selectively inhibits Alzheimer's gamma-secretase activity. Wolfe MS; Citron M; Diehl TS; Xia W; Donkor IO; Selkoe DJ J Med Chem; 1998 Jan; 41(1):6-9. PubMed ID: 9438016 [No Abstract] [Full Text] [Related]
9. [Secretases as therapeutic targets for the treatment of Alzheimer's disease]. Dejaegere T; de Strooper B Verh K Acad Geneeskd Belg; 2004; 66(1):29-58; discussion 58-9. PubMed ID: 15074081 [TBL] [Abstract][Full Text] [Related]
10. [Alzheimer's disease: focus on beta-amyloid and gamma-secretase]. Iwatsubo T Tanpakushitsu Kakusan Koso; 2004 May; 49(7 Suppl):1086-90. PubMed ID: 15168534 [No Abstract] [Full Text] [Related]
12. Beta-secretase inhibition for the treatment of Alzheimer's disease--promise and challenge. Citron M Trends Pharmacol Sci; 2004 Feb; 25(2):92-7. PubMed ID: 15102495 [TBL] [Abstract][Full Text] [Related]
13. Expression and activity of beta-site amyloid precursor protein cleaving enzyme in Alzheimer's disease. Johnston JA; Liu WW; Todd SA; Coulson DT; Murphy S; Irvine GB; Passmore AP Biochem Soc Trans; 2005 Nov; 33(Pt 5):1096-100. PubMed ID: 16246054 [TBL] [Abstract][Full Text] [Related]
14. Amyloid-beta precursor protein processing in neurodegeneration. Wilquet V; De Strooper B Curr Opin Neurobiol; 2004 Oct; 14(5):582-8. PubMed ID: 15464891 [TBL] [Abstract][Full Text] [Related]
15. Disease modifying strategies for the treatment of Alzheimer's disease targeted at modulating levels of the beta-amyloid peptide. Pangalos MN; Jacobsen SJ; Reinhart PH Biochem Soc Trans; 2005 Aug; 33(Pt 4):553-8. PubMed ID: 16042543 [TBL] [Abstract][Full Text] [Related]
16. Alzheimer's disease. Bad for the heart, bad for the mind? Marx J Science; 2001 Oct; 294(5542):508-9. PubMed ID: 11641483 [No Abstract] [Full Text] [Related]
17. Secretase inhibitors for Alzheimer's disease: challenges of a promiscuous protease. Pollack SJ; Lewis H Curr Opin Investig Drugs; 2005 Jan; 6(1):35-47. PubMed ID: 15675602 [TBL] [Abstract][Full Text] [Related]
18. Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo. Hussain I; Hawkins J; Harrison D; Hille C; Wayne G; Cutler L; Buck T; Walter D; Demont E; Howes C; Naylor A; Jeffrey P; Gonzalez MI; Dingwall C; Michel A; Redshaw S; Davis JB J Neurochem; 2007 Feb; 100(3):802-9. PubMed ID: 17156133 [TBL] [Abstract][Full Text] [Related]
19. Caspase-3 cleavage of GGA3 stabilizes BACE: implications for Alzheimer's disease. Vassar R Neuron; 2007 Jun; 54(5):671-3. PubMed ID: 17553417 [TBL] [Abstract][Full Text] [Related]
20. Tracking Alzheimer's. Roberts L US News World Rep; 1999 Nov; 127(17):73. PubMed ID: 10623301 [No Abstract] [Full Text] [Related] [Next] [New Search]