133 related articles for article (PubMed ID: 12893846)
1. A natural product ligand of the oxysterol receptor, liver X receptor.
Bramlett KS; Houck KA; Borchert KM; Dowless MS; Kulanthaivel P; Zhang Y; Beyer TP; Schmidt R; Thomas JS; Michael LF; Barr R; Montrose C; Eacho PI; Cao G; Burris TP
J Pharmacol Exp Ther; 2003 Oct; 307(1):291-6. PubMed ID: 12893846
[TBL] [Abstract][Full Text] [Related]
2. SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR.
Wong J; Quinn CM; Brown AJ
Biochem J; 2006 Dec; 400(3):485-91. PubMed ID: 16901265
[TBL] [Abstract][Full Text] [Related]
3. Liver X receptor (LXR)-beta regulation in LXRalpha-deficient mice: implications for therapeutic targeting.
Quinet EM; Savio DA; Halpern AR; Chen L; Schuster GU; Gustafsson JA; Basso MD; Nambi P
Mol Pharmacol; 2006 Oct; 70(4):1340-9. PubMed ID: 16825483
[TBL] [Abstract][Full Text] [Related]
4. Physical and functional interactions between liver X receptor/retinoid X receptor and Sp1 modulate the transcriptional induction of the human ATP binding cassette transporter A1 gene by oxysterols and retinoids.
Thymiakou E; Zannis VI; Kardassis D
Biochemistry; 2007 Oct; 46(41):11473-83. PubMed ID: 17887732
[TBL] [Abstract][Full Text] [Related]
5. Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells.
DiBlasio-Smith EA; Arai M; Quinet EM; Evans MJ; Kornaga T; Basso MD; Chen L; Feingold I; Halpern AR; Liu QY; Nambi P; Savio D; Wang S; Mounts WM; Isler JA; Slager AM; Burczynski ME; Dorner AJ; LaVallie ER
J Transl Med; 2008 Oct; 6():59. PubMed ID: 18925943
[TBL] [Abstract][Full Text] [Related]
6. T0901317 is a dual LXR/FXR agonist.
Houck KA; Borchert KM; Hepler CD; Thomas JS; Bramlett KS; Michael LF; Burris TP
Mol Genet Metab; 2004; 83(1-2):184-7. PubMed ID: 15464433
[TBL] [Abstract][Full Text] [Related]
7. Regulation of ATP-binding cassette transporter A1 transcription by thyroid hormone receptor.
Huuskonen J; Vishnu M; Pullinger CR; Fielding PE; Fielding CJ
Biochemistry; 2004 Feb; 43(6):1626-32. PubMed ID: 14769039
[TBL] [Abstract][Full Text] [Related]
8. The pharmacology of LXR.
Michael LF; Schkeryantz JM; Burris TP
Mini Rev Med Chem; 2005 Aug; 5(8):729-40. PubMed ID: 16101409
[TBL] [Abstract][Full Text] [Related]
9. Oxidized LDL downregulates ATP-binding cassette transporter-1 in human vascular endothelial cells via inhibiting liver X receptor (LXR).
Zhu Y; Liao H; Xie X; Yuan Y; Lee TS; Wang N; Wang X; Shyy JY; Stemerman MB
Cardiovasc Res; 2005 Dec; 68(3):425-32. PubMed ID: 16099444
[TBL] [Abstract][Full Text] [Related]
10. Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands.
Yang C; McDonald JG; Patel A; Zhang Y; Umetani M; Xu F; Westover EJ; Covey DF; Mangelsdorf DJ; Cohen JC; Hobbs HH
J Biol Chem; 2006 Sep; 281(38):27816-26. PubMed ID: 16857673
[TBL] [Abstract][Full Text] [Related]
11. BAREing it all: the adoption of LXR and FXR and their roles in lipid homeostasis.
Edwards PA; Kast HR; Anisfeld AM
J Lipid Res; 2002 Jan; 43(1):2-12. PubMed ID: 11792716
[TBL] [Abstract][Full Text] [Related]
12. Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux.
Wong J; Quinn CM; Brown AJ
Arterioscler Thromb Vasc Biol; 2004 Dec; 24(12):2365-71. PubMed ID: 15514210
[TBL] [Abstract][Full Text] [Related]
13. Role of p160 coactivator complex in the activation of liver X receptor.
Huuskonen J; Fielding PE; Fielding CJ
Arterioscler Thromb Vasc Biol; 2004 Apr; 24(4):703-8. PubMed ID: 14764426
[TBL] [Abstract][Full Text] [Related]
14. Discovery of substituted maleimides as liver X receptor agonists and determination of a ligand-bound crystal structure.
Jaye MC; Krawiec JA; Campobasso N; Smallwood A; Qiu C; Lu Q; Kerrigan JJ; De Los Frailes Alvaro M; Laffitte B; Liu WS; Marino JP; Meyer CR; Nichols JA; Parks DJ; Perez P; Sarov-Blat L; Seepersaud SD; Steplewski KM; Thompson SK; Wang P; Watson MA; Webb CL; Haigh D; Caravella JA; Macphee CH; Willson TM; Collins JL
J Med Chem; 2005 Aug; 48(17):5419-22. PubMed ID: 16107141
[TBL] [Abstract][Full Text] [Related]
15. A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol).
Wang Y; Kumar N; Crumbley C; Griffin PR; Burris TP
Biochim Biophys Acta; 2010 Aug; 1801(8):917-23. PubMed ID: 20211758
[TBL] [Abstract][Full Text] [Related]
16. Induction of SREBP-1c mRNA by differentiation and LXR ligand in human keratinocytes.
Yokoyama A; Makishima M; Choi M; Cho Y; Nishida S; Hashimoto Y; Terui T
J Invest Dermatol; 2009 Jun; 129(6):1395-401. PubMed ID: 19242521
[TBL] [Abstract][Full Text] [Related]
17. Riccardin C: a natural product that functions as a liver X receptor (LXR)alpha agonist and an LXRbeta antagonist.
Tamehiro N; Sato Y; Suzuki T; Hashimoto T; Asakawa Y; Yokoyama S; Kawanishi T; Ohno Y; Inoue K; Nagao T; Nishimaki-Mogami T
FEBS Lett; 2005 Oct; 579(24):5299-304. PubMed ID: 16182288
[TBL] [Abstract][Full Text] [Related]
18. Different roles of liver X receptor alpha and beta in lipid metabolism: effects of an alpha-selective and a dual agonist in mice deficient in each subtype.
Lund EG; Peterson LB; Adams AD; Lam MH; Burton CA; Chin J; Guo Q; Huang S; Latham M; Lopez JC; Menke JG; Milot DP; Mitnaul LJ; Rex-Rabe SE; Rosa RL; Tian JY; Wright SD; Sparrow CP
Biochem Pharmacol; 2006 Feb; 71(4):453-63. PubMed ID: 16325781
[TBL] [Abstract][Full Text] [Related]
19. Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor.
Deng R; Yang D; Yang J; Yan B
J Pharmacol Exp Ther; 2006 Apr; 317(1):317-25. PubMed ID: 16371446
[TBL] [Abstract][Full Text] [Related]
20. Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha.
Spencer TA; Li D; Russel JS; Collins JL; Bledsoe RK; Consler TG; Moore LB; Galardi CM; McKee DD; Moore JT; Watson MA; Parks DJ; Lambert MH; Willson TM
J Med Chem; 2001 Mar; 44(6):886-97. PubMed ID: 11300870
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
