These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

516 related articles for article (PubMed ID: 12902539)

  • 1. Proteasome inhibitors disrupt the unfolded protein response in myeloma cells.
    Lee AH; Iwakoshi NN; Anderson KC; Glimcher LH
    Proc Natl Acad Sci U S A; 2003 Aug; 100(17):9946-51. PubMed ID: 12902539
    [TBL] [Abstract][Full Text] [Related]  

  • 2. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA.
    Calfon M; Zeng H; Urano F; Till JH; Hubbard SR; Harding HP; Clark SG; Ron D
    Nature; 2002 Jan; 415(6867):92-6. PubMed ID: 11780124
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Unfolded protein response inducers tunicamycin and dithiothreitol promote myeloma cell differentiation mediated by XBP-1.
    Jiang H; Zou J; Zhang H; Fu W; Zeng T; Huang H; Zhou F; Hou J
    Clin Exp Med; 2015 Feb; 15(1):85-96. PubMed ID: 24356728
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IPI-504, a novel and soluble HSP-90 inhibitor, blocks the unfolded protein response in multiple myeloma cells.
    Patterson J; Palombella VJ; Fritz C; Normant E
    Cancer Chemother Pharmacol; 2008 May; 61(6):923-32. PubMed ID: 17624530
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Response of myeloma to the proteasome inhibitor bortezomib is correlated with the unfolded protein response regulator XBP-1.
    Ling SC; Lau EK; Al-Shabeeb A; Nikolic A; Catalano A; Iland H; Horvath N; Ho PJ; Harrison S; Fleming S; Joshua DE; Allen JD
    Haematologica; 2012 Jan; 97(1):64-72. PubMed ID: 21993678
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reduced response of IRE1α/Xbp-1 signaling pathway to bortezomib contributes to drug resistance in multiple myeloma cells.
    Xu X; Liu J; Huang B; Chen M; Yuan S; Li X; Li J
    Tumori; 2017 May; 103(3):261-267. PubMed ID: 27647225
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prolonged endoplasmic reticulum stress promotes mislocalization of immunoglobulins to the cytoplasm.
    Drori A; Misaghi S; Haimovich J; Messerle M; Tirosh B
    Mol Immunol; 2010 May; 47(9):1719-27. PubMed ID: 20353876
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human cytomegalovirus infection activates and regulates the unfolded protein response.
    Isler JA; Skalet AH; Alwine JC
    J Virol; 2005 Jun; 79(11):6890-9. PubMed ID: 15890928
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Direct proteasome binding and subsequent degradation of unspliced XBP-1 prevent its intracellular aggregation.
    Navon A; Gatushkin A; Zelcbuch L; Shteingart S; Farago M; Hadar R; Tirosh B
    FEBS Lett; 2010 Jan; 584(1):67-73. PubMed ID: 19941857
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protective effect against Parkinson's disease-related insults through the activation of XBP1.
    Sado M; Yamasaki Y; Iwanaga T; Onaka Y; Ibuki T; Nishihara S; Mizuguchi H; Momota H; Kishibuchi R; Hashimoto T; Wada D; Kitagawa H; Watanabe TK
    Brain Res; 2009 Feb; 1257():16-24. PubMed ID: 19135031
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease.
    Volkmann K; Lucas JL; Vuga D; Wang X; Brumm D; Stiles C; Kriebel D; Der-Sarkissian A; Krishnan K; Schweitzer C; Liu Z; Malyankar UM; Chiovitti D; Canny M; Durocher D; Sicheri F; Patterson JB
    J Biol Chem; 2011 Apr; 286(14):12743-55. PubMed ID: 21303903
    [TBL] [Abstract][Full Text] [Related]  

  • 12. XBP-1, a key regulator of unfolded protein response, activates transcription of IGF1 and Akt phosphorylation in zebrafish embryonic cell line.
    Hu MC; Gong HY; Lin GH; Hu SY; Chen MH; Huang SJ; Liao CF; Wu JL
    Biochem Biophys Res Commun; 2007 Aug; 359(3):778-83. PubMed ID: 17560942
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cleavage of BLOC1S1 mRNA by IRE1 Is Sequence Specific, Temporally Separate from XBP1 Splicing, and Dispensable for Cell Viability under Acute Endoplasmic Reticulum Stress.
    Bright MD; Itzhak DN; Wardell CP; Morgan GJ; Davies FE
    Mol Cell Biol; 2015 Jun; 35(12):2186-202. PubMed ID: 25870107
    [TBL] [Abstract][Full Text] [Related]  

  • 14. XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response.
    Lee AH; Iwakoshi NN; Glimcher LH
    Mol Cell Biol; 2003 Nov; 23(21):7448-59. PubMed ID: 14559994
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.
    Zhang K; Wong HN; Song B; Miller CN; Scheuner D; Kaufman RJ
    J Clin Invest; 2005 Feb; 115(2):268-81. PubMed ID: 15690081
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dinaciclib (SCH727965) inhibits the unfolded protein response through a CDK1- and 5-dependent mechanism.
    Nguyen TK; Grant S
    Mol Cancer Ther; 2014 Mar; 13(3):662-74. PubMed ID: 24362465
    [TBL] [Abstract][Full Text] [Related]  

  • 17. IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response.
    Lee K; Tirasophon W; Shen X; Michalak M; Prywes R; Okada T; Yoshida H; Mori K; Kaufman RJ
    Genes Dev; 2002 Feb; 16(4):452-66. PubMed ID: 11850408
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of the unfolded protein response is required for defenses against bacterial pore-forming toxin in vivo.
    Bischof LJ; Kao CY; Los FC; Gonzalez MR; Shen Z; Briggs SP; van der Goot FG; Aroian RV
    PLoS Pathog; 2008 Oct; 4(10):e1000176. PubMed ID: 18846208
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BCL-2 modulates the unfolded protein response by enhancing splicing of X-box binding protein-1.
    Chonghaile TN; Gupta S; John M; Szegezdi E; Logue SE; Samali A
    Biochem Biophys Res Commun; 2015 Oct; 466(1):40-5. PubMed ID: 26319553
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease.
    Puri P; Mirshahi F; Cheung O; Natarajan R; Maher JW; Kellum JM; Sanyal AJ
    Gastroenterology; 2008 Feb; 134(2):568-76. PubMed ID: 18082745
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.