186 related articles for article (PubMed ID: 12904040)
1. Structure-based design of a highly selective catalytic site-directed inhibitor of Ser/Thr protein phosphatase 2B (calcineurin).
Baba Y; Hirukawa N; Tanohira N; Sodeoka M
J Am Chem Soc; 2003 Aug; 125(32):9740-9. PubMed ID: 12904040
[TBL] [Abstract][Full Text] [Related]
2. Optically active cantharidin analogues possessing selective inhibitory activity on Ser/Thr protein phosphatase 2B (calcineurin): implications for the binding mode.
Baba Y; Hirukawa N; Sodeoka M
Bioorg Med Chem; 2005 Sep; 13(17):5164-70. PubMed ID: 15951185
[TBL] [Abstract][Full Text] [Related]
3. The inhibition of protein phosphatases 1 and 2A: a new target for rational anti-cancer drug design?
McCluskey A; Ackland SP; Gardiner E; Walkom CC; Sakoff JA
Anticancer Drug Des; 2001 Dec; 16(6):291-303. PubMed ID: 12375882
[TBL] [Abstract][Full Text] [Related]
4. FTDP-17 missense mutations site-specifically inhibit as well as promote dephosphorylation of microtubule-associated protein tau by protein phosphatases of HEK-293 cell extract.
Han D; Paudel HK
Neurochem Int; 2009 Jan; 54(1):14-27. PubMed ID: 18992292
[TBL] [Abstract][Full Text] [Related]
5. Cantharidin analogues: synthesis and evaluation of growth inhibition in a panel of selected tumour cell lines.
McCluskey A; Ackland SP; Bowyer MC; Baldwin ML; Garner J; Walkom CC; Sakoff JA
Bioorg Chem; 2003 Feb; 31(1):68-79. PubMed ID: 12697169
[TBL] [Abstract][Full Text] [Related]
6. Cantharimides: a new class of modified cantharidin analogues inhibiting protein phosphatases 1 and 2A.
McCluskey A; Walkom C; Bowyer MC; Ackland SP; Gardiner E; Sakoff JA
Bioorg Med Chem Lett; 2001 Nov; 11(22):2941-6. PubMed ID: 11677131
[TBL] [Abstract][Full Text] [Related]
7. The nonconserved N-terminus of protein phosphatase 2B confers its properties to protein phosphatase 1.
Xie XJ; Huang W; Xue CZ; Wei Q
IUBMB Life; 2009 Feb; 61(2):178-83. PubMed ID: 18925649
[TBL] [Abstract][Full Text] [Related]
8. Heterocyclic substituted cantharidin and norcantharidin analogues--synthesis, protein phosphatase (1 and 2A) inhibition, and anti-cancer activity.
Hill TA; Stewart SG; Sauer B; Gilbert J; Ackland SP; Sakoff JA; McCluskey A
Bioorg Med Chem Lett; 2007 Jun; 17(12):3392-7. PubMed ID: 17451951
[TBL] [Abstract][Full Text] [Related]
9. Cytotoxicity of cantharidin analogues targeting protein phosphatase 2A.
Shan HB; Cai YC; Liu Y; Zeng WN; Chen HX; Fan BT; Liu XH; Xu ZL; Wang B; Xian LJ
Anticancer Drugs; 2006 Sep; 17(8):905-11. PubMed ID: 16940800
[TBL] [Abstract][Full Text] [Related]
10. Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation.
Liu F; Grundke-Iqbal I; Iqbal K; Gong CX
Eur J Neurosci; 2005 Oct; 22(8):1942-50. PubMed ID: 16262633
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and biological activity of Delta-5,6-norcantharimides: importance of the 5,6-bridge.
Thaqi A; Scott JL; Gilbert J; Sakoff JA; McCluskey A
Eur J Med Chem; 2010 May; 45(5):1717-23. PubMed ID: 20153915
[TBL] [Abstract][Full Text] [Related]
12. Norcantharidin analogues: synthesis, anticancer activity and protein phosphatase 1 and 2A inhibition.
Hill TA; Stewart SG; Gordon CP; Ackland SP; Gilbert J; Sauer B; Sakoff JA; McCluskey A
ChemMedChem; 2008 Dec; 3(12):1878-92. PubMed ID: 19025735
[TBL] [Abstract][Full Text] [Related]
13. Structural basis of serine/threonine phosphatase inhibition by the archetypal small molecules cantharidin and norcantharidin.
Bertini I; Calderone V; Fragai M; Luchinat C; Talluri E
J Med Chem; 2009 Aug; 52(15):4838-43. PubMed ID: 19601647
[TBL] [Abstract][Full Text] [Related]
14. K restriction inhibits protein phosphatase 2B (PP2B) and suppression of PP2B decreases ROMK channel activity in the CCD.
Zhang Y; Lin DH; Wang ZJ; Jin Y; Yang B; Wang WH
Am J Physiol Cell Physiol; 2008 Mar; 294(3):C765-73. PubMed ID: 18184875
[TBL] [Abstract][Full Text] [Related]
15. Regulation of the catalytic domain of protein phosphatase 1 by the terminal region of protein phosphatase 2B.
Wang BJ; Tang W; Zhang P; Wei Q
J Biochem; 2012 Mar; 151(3):283-90. PubMed ID: 22247559
[TBL] [Abstract][Full Text] [Related]
16. Regulation of dopamine D-receptor activation in vivo by protein phosphatase 2B (calcineurin).
Adlersberg M; Hsiung SC; Glickstein SB; Liu KP; Tamir H; Schmauss C
J Neurochem; 2004 Aug; 90(4):865-73. PubMed ID: 15287892
[TBL] [Abstract][Full Text] [Related]
17. Infusion of FK506, a specific inhibitor of calcineurin, induces potent tau hyperphosphorylation in mouse brain.
Luo J; Ma J; Yu DY; Bu F; Zhang W; Tu LH; Wei Q
Brain Res Bull; 2008 Jul; 76(5):464-8. PubMed ID: 18534252
[TBL] [Abstract][Full Text] [Related]
18. The primary identification of a calcineurin A subunit-like protein in plants.
Yang C; Song H; Weng H; Wei Q
Biochimie; 2009 May; 91(5):646-9. PubMed ID: 19146913
[TBL] [Abstract][Full Text] [Related]
19. Synthesis of optically pure norcantharidin analogue NCA-01, a highly selective protein phosphatase 2B inhibitor, and its derivatives.
Shimizu T; Iizuka M; Matsukura H; Hashizume D; Sodeoka M
Chem Asian J; 2012 Jun; 7(6):1221-30. PubMed ID: 22488808
[TBL] [Abstract][Full Text] [Related]
20. Studies of small molecule interactions with protein phosphatases using biosensor technology.
Stenlund P; Frostell-Karlsson A; Karlsson OP
Anal Biochem; 2006 Jun; 353(2):217-25. PubMed ID: 16597430
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
