247 related articles for article (PubMed ID: 12904081)
1. Synthesis and evaluation of pharmacological properties of novel annelated 2,3-benzodiazepine derivatives.
Gitto R; Orlando V; Quartarone S; De Sarro G; De Sarro A; Russo E; Ferreri G; Chimirri A
J Med Chem; 2003 Aug; 46(17):3758-61. PubMed ID: 12904081
[TBL] [Abstract][Full Text] [Related]
2. 3,5-Dihydro-4H-2,3-benzodiazepine-4-thiones: a new class of AMPA receptor antagonists.
Chimirri A; De Sarro G; De Sarro A; Gitto R; Quartarone S; Zappalà M; Constanti A; Libri V
J Med Chem; 1998 Aug; 41(18):3409-16. PubMed ID: 9719593
[TBL] [Abstract][Full Text] [Related]
3. 1-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: novel AMPA receptor antagonists.
Chimirri A; De Sarro G; De Sarro A; Gitto R; Grasso S; Quartarone S; Zappalà M; Giusti P; Libri V; Constanti A; Chapman AG
J Med Chem; 1997 Apr; 40(8):1258-69. PubMed ID: 9111300
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and evaluation of pharmacological and pharmacokinetic properties of 11H-[1,2,4]triazolo[4,5-c][2,3]benzodiazepin-3(2H)-ones.
Zappalà M; Gitto R; Bevacqua F; Quartarone S; Chimirri A; Rizzo M; De Sarro G; De Sarro A
J Med Chem; 2000 Dec; 43(25):4834-9. PubMed ID: 11123993
[TBL] [Abstract][Full Text] [Related]
5. Novel potent anticonvulsant agent containing a tetrahydroisoquinoline skeleton.
Gitto R; Caruso R; Pagano B; De Luca L; Citraro R; Russo E; De Sarro G; Chimirri A
J Med Chem; 2006 Sep; 49(18):5618-22. PubMed ID: 16942035
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and anticonvulsant activity of novel and potent 2,3-benzodiazepine AMPA/kainate receptor antagonists.
Grasso S; De Sarro G; De Sarro A; Micale N; Zappalà M; Puia G; Baraldi M; De Micheli C
J Med Chem; 1999 Oct; 42(21):4414-21. PubMed ID: 10543885
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and anticonvulsant activity of novel and potent 6,7-methylenedioxyphthalazin-1(2H)-ones.
Grasso S; De Sarro G; De Sarro A; Micale N; Zappalà M; Puja G; Baraldi M; De Micheli C
J Med Chem; 2000 Jul; 43(15):2851-9. PubMed ID: 10956193
[TBL] [Abstract][Full Text] [Related]
8. Discovery of a novel and highly potent noncompetitive AMPA receptor antagonist.
Gitto R; Barreca ML; De Luca L; De Sarro G; Ferreri G; Quartarone S; Russo E; Constanti A; Chimirri A
J Med Chem; 2003 Jan; 46(1):197-200. PubMed ID: 12502375
[TBL] [Abstract][Full Text] [Related]
9. Synthesis, chiral resolution, and enantiopharmacology of a potent 2,3-benzodiazepine derivative as noncompetitive AMPA receptor antagonist.
Zappalà M; Postorino G; Micale N; Caccamese S; Parrinello N; Grazioso G; Roda G; Menniti FS; De Sarro G; Grasso S
J Med Chem; 2006 Jan; 49(2):575-81. PubMed ID: 16420043
[TBL] [Abstract][Full Text] [Related]
10. Novel potent AMPA/kainate receptor antagonists: synthesis and anticonvulsant activity of a series of 2-[(4-alkylsemicarbazono)-(4-amino-phenyl)methyl]-4,5-methylenedioxyphenylacetic acid alkyl esters.
Micale N; Zappalà M; Grasso S; Puja G; De Sarro G; Ferreri G; De Sarro A; Toma L; De Micheli C
J Med Chem; 2002 Sep; 45(20):4433-42. PubMed ID: 12238923
[TBL] [Abstract][Full Text] [Related]
11. Synthesis of some new substituted triazolo [4,3-a][1,4] benzodiazepine derivatives as potent anticonvulsants.
Narayana B; Vijaya Raj KK; Ashalatha BV; Kumari NS
Eur J Med Chem; 2006 Mar; 41(3):417-22. PubMed ID: 16472891
[TBL] [Abstract][Full Text] [Related]
12. Novel alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor antagonists of 2,3-benzodiazepine type: chemical synthesis, in vitro characterization, and in vivo prevention of acute neurodegeneration.
Elger B; Huth A; Neuhaus R; Ottow E; Schneider H; Seilheimer B; Turski L
J Med Chem; 2005 Jul; 48(14):4618-27. PubMed ID: 15999999
[TBL] [Abstract][Full Text] [Related]
13. RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis.
Canton T; Böhme GA; Boireau A; Bordier F; Mignani S; Jimonet P; Jahn G; Alavijeh M; Stygall J; Roberts S; Brealey C; Vuilhorgne M; Debono MW; Le Guern S; Laville M; Briet D; Roux M; Stutzmann JM; Pratt J
J Pharmacol Exp Ther; 2001 Oct; 299(1):314-22. PubMed ID: 11561094
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and pharmacological properties of new 3-ethoxycarbonyl-11H-[1,2,4]triazolo[4,5-c][2,3]benzodiazepines.
Chimirri A; Gitto R; Quartarone S; Orlando V; De Sarro A; De Sarro GB
Farmaco; 2002 Sep; 57(9):759-63. PubMed ID: 12385527
[TBL] [Abstract][Full Text] [Related]
15. New 7,8-ethylenedioxy-2,3-benzodiazepines as noncompetitive AMPA receptor antagonists.
Zappalà M; Pellicanò A; Micale N; Menniti FS; Ferreri G; De Sarro G; Grasso S; De Micheli C
Bioorg Med Chem Lett; 2006 Jan; 16(1):167-70. PubMed ID: 16216501
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and anticonvulsant activity of N-3 substituted 2,3-benzodiazepines.
Quartarone S; Caruso R; Orlando V; Russo E; De Sarro G; Chimirri A
Farmaco; 2004 May; 59(5):353-8. PubMed ID: 15120314
[TBL] [Abstract][Full Text] [Related]
17. New non competitive AMPA antagonists.
Abrahám G; Sólyom S; Csuzdi E; Berzsenyi P; Ling I; Tarnawa I; Hámori T; Pallagi I; Horváth K; Andrási F; Kapus G; Hársing LG; Király I; Patthy M; Horváth G
Bioorg Med Chem; 2000 Aug; 8(8):2127-43. PubMed ID: 11003158
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and anticonvulsant evaluation of N-substituted isoquinoline AMPA receptor antagonists.
Gitto R; De Luca L; Pagano B; Citraro R; De Sarro G; Costa L; Ciranna L; Chimirri A
Bioorg Med Chem; 2008 Mar; 16(5):2379-84. PubMed ID: 18077172
[TBL] [Abstract][Full Text] [Related]
19. Synthesis of 7,8-(methylenedioxy)-1-phenyl-3,5-dihydro-4H-2, 3-benzodiazepin-4-ones as novel and potent noncompetitive AMPA receptor antagonists.
Wang Y; Konkoy CS; Ilyin VI; Vanover KE; Carter RB; Weber E; Keana JF; Woodward RM; Cai SX
J Med Chem; 1998 Jul; 41(14):2621-5. PubMed ID: 9651166
[TBL] [Abstract][Full Text] [Related]
20. AMPA receptor agonists: synthesis, protolytic properties, and pharmacology of 3-isothiazolol bioisosteres of glutamic acid.
Matzen L; Engesgaard A; Ebert B; Didriksen M; Frølund B; Krogsgaard-Larsen P; Jaroszewski JW
J Med Chem; 1997 Feb; 40(4):520-7. PubMed ID: 9046343
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
