BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 12905530)

  • 1. Expression of class III beta-tubulin reduces microtubule assembly and confers resistance to paclitaxel.
    Hari M; Yang H; Zeng C; Canizales M; Cabral F
    Cell Motil Cytoskeleton; 2003 Sep; 56(1):45-56. PubMed ID: 12905530
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modulation of endogenous beta-tubulin isotype expression as a result of human beta(III)cDNA transfection into prostate carcinoma cells.
    Ranganathan S; McCauley RA; Dexter DW; Hudes GR
    Br J Cancer; 2001 Sep; 85(5):735-40. PubMed ID: 11531260
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Overexpression of an epitope-tagged beta-tubulin in Chinese hamster ovary cells causes an increase in endogenous alpha-tubulin synthesis.
    Gonzalez-Garay ML; Cabral F
    Cell Motil Cytoskeleton; 1995; 31(4):259-72. PubMed ID: 7553913
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutations at leucine 215 of beta-tubulin affect paclitaxel sensitivity by two distinct mechanisms.
    Wang Y; Yin S; Blade K; Cooper G; Menick DR; Cabral F
    Biochemistry; 2006 Jan; 45(1):185-94. PubMed ID: 16388594
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Intra-allelic suppression of a mutation that stabilizes microtubules and confers resistance to colcemid.
    Wang Y; Veeraraghavan S; Cabral F
    Biochemistry; 2004 Jul; 43(28):8965-73. PubMed ID: 15248754
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Over-expression of betaI tubulin in MDCK cells and incorporation of exogenous betaI tubulin into microtubules interferes with adhesion and spreading.
    Lezama R; Castillo A; Ludueña RF; Meza I
    Cell Motil Cytoskeleton; 2001 Nov; 50(3):147-60. PubMed ID: 11807936
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Class III beta-tubulin mediates sensitivity to chemotherapeutic drugs in non small cell lung cancer.
    Gan PP; Pasquier E; Kavallaris M
    Cancer Res; 2007 Oct; 67(19):9356-63. PubMed ID: 17909044
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of betaIII- and betaIV-tubulin isotypes in cold-adapted microtubules from Atlantic cod (Gadus morhua): antibody mapping and cDNA sequencing.
    Modig C; Olsson PE; Barasoain I; de Ines C; Andreu JM; Roach MC; Ludueña RF; Wallin M
    Cell Motil Cytoskeleton; 1999; 42(4):315-30. PubMed ID: 10223637
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Overexpression of class I, II or IVb beta-tubulin isotypes in CHO cells is insufficient to confer resistance to paclitaxel.
    Blade K; Menick DR; Cabral F
    J Cell Sci; 1999 Jul; 112 ( Pt 13)():2213-21. PubMed ID: 10362551
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression of beta-tubulin isotypes in human ovarian carcinoma xenografts and in a sub-panel of human cancer cell lines from the NCI-Anticancer Drug Screen: correlation with sensitivity to microtubule active agents.
    Nicoletti MI; Valoti G; Giannakakou P; Zhan Z; Kim JH; Lucchini V; Landoni F; Mayo JG; Giavazzi R; Fojo T
    Clin Cancer Res; 2001 Sep; 7(9):2912-22. PubMed ID: 11555610
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alterations in gamma-actin and tubulin-targeted drug resistance in childhood leukemia.
    Verrills NM; Po'uha ST; Liu ML; Liaw TY; Larsen MR; Ivery MT; Marshall GM; Gunning PW; Kavallaris M
    J Natl Cancer Inst; 2006 Oct; 98(19):1363-74. PubMed ID: 17018783
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The microtubule-stabilizing agent discodermolide competitively inhibits the binding of paclitaxel (Taxol) to tubulin polymers, enhances tubulin nucleation reactions more potently than paclitaxel, and inhibits the growth of paclitaxel-resistant cells.
    Kowalski RJ; Giannakakou P; Gunasekera SP; Longley RE; Day BW; Hamel E
    Mol Pharmacol; 1997 Oct; 52(4):613-22. PubMed ID: 9380024
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Increased levels of tyrosinated alpha-, beta(III)-, and beta(IV)-tubulin isotypes in paclitaxel-resistant MCF-7 breast cancer cells.
    Banerjee A
    Biochem Biophys Res Commun; 2002 Apr; 293(1):598-601. PubMed ID: 12054644
    [TBL] [Abstract][Full Text] [Related]  

  • 14. BetaIII-tubulin induces paclitaxel resistance in association with reduced effects on microtubule dynamic instability.
    Kamath K; Wilson L; Cabral F; Jordan MA
    J Biol Chem; 2005 Apr; 280(13):12902-7. PubMed ID: 15695826
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Microtubule disruption induced in vivo by alkylation of beta-tubulin by 1-aryl-3-(2-chloroethyl)ureas, a novel class of soft alkylating agents.
    Legault J; Gaulin JF; Mounetou E; Bolduc S; Lacroix J; Poyet P; Gaudreault RC
    Cancer Res; 2000 Feb; 60(4):985-92. PubMed ID: 10706114
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tumor cells resistant to a microtubule-depolymerizing hemiasterlin analogue, HTI-286, have mutations in alpha- or beta-tubulin and increased microtubule stability.
    Poruchynsky MS; Kim JH; Nogales E; Annable T; Loganzo F; Greenberger LM; Sackett DL; Fojo T
    Biochemistry; 2004 Nov; 43(44):13944-54. PubMed ID: 15518543
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Taxol differentially modulates the dynamics of microtubules assembled from unfractionated and purified beta-tubulin isotypes.
    Derry WB; Wilson L; Khan IA; Luduena RF; Jordan MA
    Biochemistry; 1997 Mar; 36(12):3554-62. PubMed ID: 9132006
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry.
    Verdier-Pinard P; Wang F; Martello L; Burd B; Orr GA; Horwitz SB
    Biochemistry; 2003 May; 42(18):5349-57. PubMed ID: 12731876
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential assembly kinetics of alpha-tubulin isoforms in the presence of paclitaxel.
    Banerjee A; Kasmala LT
    Biochem Biophys Res Commun; 1998 Apr; 245(2):349-51. PubMed ID: 9571153
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The roles of cys124 and ser239 in the functional properties of human betaIII tubulin.
    Joe PA; Banerjee A; Ludueña RF
    Cell Motil Cytoskeleton; 2008 Jun; 65(6):476-86. PubMed ID: 18435451
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.