BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1515 related articles for article (PubMed ID: 12907607)

  • 1. Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1.
    Shishodia S; Majumdar S; Banerjee S; Aggarwal BB
    Cancer Res; 2003 Aug; 63(15):4375-83. PubMed ID: 12907607
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Betulinic acid suppresses carcinogen-induced NF-kappa B activation through inhibition of I kappa B alpha kinase and p65 phosphorylation: abrogation of cyclooxygenase-2 and matrix metalloprotease-9.
    Takada Y; Aggarwal BB
    J Immunol; 2003 Sep; 171(6):3278-86. PubMed ID: 12960358
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates activation of cigarette smoke-induced nuclear factor (NF)-kappaB by suppressing activation of IkappaBalpha kinase in human non-small cell lung carcinoma: correlation with suppression of cyclin D1, COX-2, and matrix metalloproteinase-9.
    Shishodia S; Aggarwal BB
    Cancer Res; 2004 Jul; 64(14):5004-12. PubMed ID: 15256475
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes.
    Shukla S; Gupta S
    Clin Cancer Res; 2004 May; 10(9):3169-78. PubMed ID: 15131058
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Piceatannol inhibits TNF-induced NF-kappaB activation and NF-kappaB-mediated gene expression through suppression of IkappaBalpha kinase and p65 phosphorylation.
    Ashikawa K; Majumdar S; Banerjee S; Bharti AC; Shishodia S; Aggarwal BB
    J Immunol; 2002 Dec; 169(11):6490-7. PubMed ID: 12444159
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synthesis.
    Shishodia S; Koul D; Aggarwal BB
    J Immunol; 2004 Aug; 173(3):2011-22. PubMed ID: 15265936
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Curcumin (diferuloylmethane) down-regulates cigarette smoke-induced NF-kappaB activation through inhibition of IkappaBalpha kinase in human lung epithelial cells: correlation with suppression of COX-2, MMP-9 and cyclin D1.
    Shishodia S; Potdar P; Gairola CG; Aggarwal BB
    Carcinogenesis; 2003 Jul; 24(7):1269-79. PubMed ID: 12807725
    [TBL] [Abstract][Full Text] [Related]  

  • 8. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products.
    Shishodia S; Gutierrez AM; Lotan R; Aggarwal BB
    Cancer Res; 2005 Oct; 65(20):9555-65. PubMed ID: 16230421
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Flavopiridol inhibits NF-kappaB activation induced by various carcinogens and inflammatory agents through inhibition of IkappaBalpha kinase and p65 phosphorylation: abrogation of cyclin D1, cyclooxygenase-2, and matrix metalloprotease-9.
    Takada Y; Aggarwal BB
    J Biol Chem; 2004 Feb; 279(6):4750-9. PubMed ID: 14630924
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products.
    Ichikawa H; Takada Y; Murakami A; Aggarwal BB
    J Immunol; 2005 Jun; 174(11):7383-92. PubMed ID: 15905586
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells.
    Shishodia S; Sethi G; Konopleva M; Andreeff M; Aggarwal BB
    Clin Cancer Res; 2006 Mar; 12(6):1828-38. PubMed ID: 16551868
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor.
    Takada Y; Fang X; Jamaluddin MS; Boyd DD; Aggarwal BB
    J Biol Chem; 2004 Sep; 279(38):39541-54. PubMed ID: 15252041
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis.
    Takada Y; Singh S; Aggarwal BB
    J Biol Chem; 2004 Apr; 279(15):15096-104. PubMed ID: 14711835
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation.
    Sung B; Pandey MK; Aggarwal BB
    Mol Pharmacol; 2007 Jun; 71(6):1703-14. PubMed ID: 17387141
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway.
    Ahn KS; Sethi G; Shishodia S; Sung B; Arbiser JL; Aggarwal BB
    Mol Cancer Res; 2006 Sep; 4(9):621-33. PubMed ID: 16966432
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation.
    Aggarwal S; Ichikawa H; Takada Y; Sandur SK; Shishodia S; Aggarwal BB
    Mol Pharmacol; 2006 Jan; 69(1):195-206. PubMed ID: 16219905
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cigarette smoke condensate activates nuclear transcription factor-kappaB through phosphorylation and degradation of IkappaB(alpha): correlation with induction of cyclooxygenase-2.
    Anto RJ; Mukhopadhyay A; Shishodia S; Gairola CG; Aggarwal BB
    Carcinogenesis; 2002 Sep; 23(9):1511-8. PubMed ID: 12189195
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Suppression of RelA/p65 nuclear translocation independent of IkappaB-alpha degradation by cyclooxygenase-2 inhibitor in gastric cancer.
    Wong BC; Jiang Xh; Fan XM; Lin MC; Jiang SH; Lam SK; Kung HF
    Oncogene; 2003 Feb; 22(8):1189-97. PubMed ID: 12606945
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Indole-3-carbinol suppresses NF-kappaB and IkappaBalpha kinase activation, causing inhibition of expression of NF-kappaB-regulated antiapoptotic and metastatic gene products and enhancement of apoptosis in myeloid and leukemia cells.
    Takada Y; Andreeff M; Aggarwal BB
    Blood; 2005 Jul; 106(2):641-9. PubMed ID: 15811958
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis.
    Sethi G; Ahn KS; Sung B; Aggarwal BB
    Mol Cancer Ther; 2008 Jun; 7(6):1604-14. PubMed ID: 18566231
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 76.