BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

240 related articles for article (PubMed ID: 12907674)

  • 1. WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation.
    Magnifico A; Ettenberg S; Yang C; Mariano J; Tiwari S; Fang S; Lipkowitz S; Weissman AM
    J Biol Chem; 2003 Oct; 278(44):43169-77. PubMed ID: 12907674
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of developmentally expressed proteins that functionally interact with Nedd4 ubiquitin ligase.
    Murillas R; Simms KS; Hatakeyama S; Weissman AM; Kuehn MR
    J Biol Chem; 2002 Jan; 277(4):2897-907. PubMed ID: 11717310
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiation.
    Kaabeche K; Lemonnier J; Le Mée S; Caverzasio J; Marie PJ
    J Biol Chem; 2004 Aug; 279(35):36259-67. PubMed ID: 15190072
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nedd4 regulates ubiquitination and stability of the guanine-nucleotide exchange factor CNrasGEF.
    Pham N; Rotin D
    J Biol Chem; 2001 Dec; 276(50):46995-7003. PubMed ID: 11598133
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases.
    Morén A; Imamura T; Miyazono K; Heldin CH; Moustakas A
    J Biol Chem; 2005 Jun; 280(23):22115-23. PubMed ID: 15817471
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7.
    Yokouchi M; Kondo T; Houghton A; Bartkiewicz M; Horne WC; Zhang H; Yoshimura A; Baron R
    J Biol Chem; 1999 Oct; 274(44):31707-12. PubMed ID: 10531381
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2.
    Chan W; Tian R; Lee YF; Sit ST; Lim L; Manser E
    J Biol Chem; 2009 Mar; 284(12):8185-94. PubMed ID: 19144635
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substrate proteolysis is inhibited by dominant-negative Nedd4 and Rsp5 mutants harboring alterations in WW domain 1.
    Shcherbik N; Kumar S; Haines DS
    J Cell Sci; 2002 Mar; 115(Pt 5):1041-8. PubMed ID: 11870222
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Itch WW Domains Inhibit Its E3 Ubiquitin Ligase Activity by Blocking E2-E3 Ligase Trans-thiolation.
    Riling C; Kamadurai H; Kumar S; O'Leary CE; Wu KP; Manion EE; Ying M; Schulman BA; Oliver PM
    J Biol Chem; 2015 Sep; 290(39):23875-87. PubMed ID: 26245901
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor.
    Vecchione A; Marchese A; Henry P; Rotin D; Morrione A
    Mol Cell Biol; 2003 May; 23(9):3363-72. PubMed ID: 12697834
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops.
    Rubin C; Litvak V; Medvedovsky H; Zwang Y; Lev S; Yarden Y
    Curr Biol; 2003 Feb; 13(4):297-307. PubMed ID: 12593795
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cbl-mediated ubiquitination of alpha5 integrin subunit mediates fibronectin-dependent osteoblast detachment and apoptosis induced by FGFR2 activation.
    Kaabeche K; Guenou H; Bouvard D; Didelot N; Listrat A; Marie PJ
    J Cell Sci; 2005 Mar; 118(Pt 6):1223-32. PubMed ID: 15728256
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations.
    Kassenbrock CK; Anderson SM
    J Biol Chem; 2004 Jul; 279(27):28017-27. PubMed ID: 15117950
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH.
    Courbard JR; Fiore F; Adélaïde J; Borg JP; Birnbaum D; Ollendorff V
    J Biol Chem; 2002 Nov; 277(47):45267-75. PubMed ID: 12226085
    [TBL] [Abstract][Full Text] [Related]  

  • 15. hSpry2 is targeted to the ubiquitin-dependent proteasome pathway by c-Cbl.
    Hall AB; Jura N; DaSilva J; Jang YJ; Gong D; Bar-Sagi D
    Curr Biol; 2003 Feb; 13(4):308-14. PubMed ID: 12593796
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK.
    Lin Q; Wang J; Childress C; Sudol M; Carey DJ; Yang W
    Mol Cell Biol; 2010 Mar; 30(6):1541-54. PubMed ID: 20086093
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Different HECT domain ubiquitin ligases employ distinct mechanisms of polyubiquitin chain synthesis.
    Wang M; Pickart CM
    EMBO J; 2005 Dec; 24(24):4324-33. PubMed ID: 16341092
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53.
    Rajendra R; Malegaonkar D; Pungaliya P; Marshall H; Rasheed Z; Brownell J; Liu LF; Lutzker S; Saleem A; Rubin EH
    J Biol Chem; 2004 Aug; 279(35):36440-4. PubMed ID: 15247280
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis.
    Huang F; Sorkin A
    Mol Biol Cell; 2005 Mar; 16(3):1268-81. PubMed ID: 15635092
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ubiquitinylation and proteasome-dependent degradation of the phosphoinositide-specific phospholipase C gamma 1 in A-431 cells.
    Evdonin AL; Tsupkina NV; Nikol'skii NN; Medvedeva ND
    Dokl Biol Sci; 2003; 392():456-7. PubMed ID: 14650885
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 12.