BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

124 related articles for article (PubMed ID: 12907759)

  • 1. Epitope map for a growth hormone receptor agonist monoclonal antibody, MAb 263.
    Wan Y; Zheng YZ; Harris JM; Brown R; Waters MJ
    Mol Endocrinol; 2003 Nov; 17(11):2240-50. PubMed ID: 12907759
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A conformationally sensitive GHR [growth hormone (GH) receptor] antibody: impact on GH signaling and GHR proteolysis.
    Jiang J; Wang X; He K; Li X; Chen C; Sayeski PP; Waters MJ; Frank SJ
    Mol Endocrinol; 2004 Dec; 18(12):2981-96. PubMed ID: 15345746
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibitory GH receptor extracellular domain monoclonal antibodies: three-dimensional epitope mapping.
    Jiang J; Wan Y; Wang X; Xu J; Harris JM; Lobie PE; Zhang Y; Zinn KR; Waters MJ; Frank SJ
    Endocrinology; 2011 Dec; 152(12):4777-88. PubMed ID: 21990310
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neutralization of NGF-TrkA receptor interaction by the novel antagonistic anti-TrkA monoclonal antibody MNAC13: a structural insight.
    Covaceuszach S; Cattaneo A; Lamba D
    Proteins; 2005 Feb; 58(3):717-27. PubMed ID: 15625712
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of chimeric and full-length growth hormone receptors by growth hormone receptor monoclonal antibodies. A specific conformational change may be required for full-length receptor signaling.
    Rowlinson SW; Behncken SN; Rowland JE; Clarkson RW; Strasburger CJ; Wu Z; Baumbach W; Waters MJ
    J Biol Chem; 1998 Feb; 273(9):5307-14. PubMed ID: 9478989
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen.
    Chen Y; Wiesmann C; Fuh G; Li B; Christinger HW; McKay P; de Vos AM; Lowman HB
    J Mol Biol; 1999 Nov; 293(4):865-81. PubMed ID: 10543973
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mapping and molecular characterization of novel monoclonal antibodies to conformational epitopes on NH2 and COOH termini of mammalian tryptophanyl-tRNA synthetase reveal link of the epitopes to aggregation and Alzheimer's disease.
    Paley EL; Smelyanski L; Malinovskii V; Subbarayan PR; Berdichevsky Y; Posternak N; Gershoni JM; Sokolova O; Denisova G
    Mol Immunol; 2007 Jan; 44(4):541-57. PubMed ID: 16616781
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge.
    Malia TJ; Teplyakov A; Brezski RJ; Luo J; Kinder M; Sweet RW; Almagro JC; Jordan RE; Gilliland GL
    Proteins; 2014 Aug; 82(8):1656-67. PubMed ID: 24638881
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Epitope mapping and structural analysis of an anti-ErbB2 antibody A21: Molecular basis for tumor inhibitory mechanism.
    Hu S; Zhu Z; Li L; Chang L; Li W; Cheng L; Teng M; Liu J
    Proteins; 2008 Feb; 70(3):938-49. PubMed ID: 17847085
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The crystal structure of the pathogenic collagen type II-specific mouse monoclonal antibody CIIC1 Fab: structure to function analysis.
    Uysal H; Sehnert B; Nandakumar KS; Böiers U; Burkhardt H; Holmdahl R; Thunnissen MM
    Mol Immunol; 2008 Apr; 45(8):2196-204. PubMed ID: 18241923
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of the growth hormone (GH) receptor transmembrane domain in receptor predimerization and GH-induced activation.
    Yang N; Wang X; Jiang J; Frank SJ
    Mol Endocrinol; 2007 Jul; 21(7):1642-55. PubMed ID: 17456794
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterisation of an autoreactive conformational epitope on GAD65 recognised by the human monoclonal antibody b78 using a combination of phage display, in vitro mutagenesis and molecular modelling.
    O'Connor KH; Banga JP; Darmanin C; El-Kabbani O; Mackay IR; Rowley MJ
    J Autoimmun; 2006 May; 26(3):172-81. PubMed ID: 16564157
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure of the Fab fragment of the anti-murine EGFR antibody 7A7 and exploration of its receptor binding site.
    Talavera A; Mackenzie J; Garrido G; Friemann R; López-Requena A; Moreno E; Krengel U
    Mol Immunol; 2011 Jul; 48(12-13):1578-85. PubMed ID: 21592580
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Location of a protease-hypersensitive region in the multidrug resistance protein (MRP) by mapping of the epitope of MRP-specific monoclonal antibody QCRL-1.
    Hipfner DR; Almquist KC; Stride BD; Deeley RG; Cole SP
    Cancer Res; 1996 Jul; 56(14):3307-14. PubMed ID: 8764126
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations.
    Vafa O; Gilliland GL; Brezski RJ; Strake B; Wilkinson T; Lacy ER; Scallon B; Teplyakov A; Malia TJ; Strohl WR
    Methods; 2014 Jan; 65(1):114-26. PubMed ID: 23872058
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Precise epitope determination of the anti-vimentin monoclonal antibody V9.
    Tomiyama L; Kamino H; Fukamachi H; Urano T
    Mol Med Rep; 2017 Oct; 16(4):3917-3921. PubMed ID: 28765898
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HLA (A*0201) mimicry by anti-idiotypic monoclonal antibodies.
    Burlingham WJ; Jankowska-Gan E; DeVito-Haynes L; Fechner JH; Hogan KT; Claas FH; Mulder A; Wang X; Ferrone S
    J Immunol; 1998 Dec; 161(12):6705-14. PubMed ID: 9862700
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential mapping of Fc gamma-binding and monoclonal antibody-reactive epitopes on gE, the Fc gamma-binding glycoprotein of herpes simplex virus type 1.
    Williams RC; Kievit E; Tsuchiya N; Malone C; Hutt-Fletcher L
    J Immunol; 1992 Oct; 149(7):2415-27. PubMed ID: 1382102
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cross-reactive binding of cyclic peptides to an anti-TGFalpha antibody Fab fragment: an X-ray structural and thermodynamic analysis.
    Hahn M; Winkler D; Welfle K; Misselwitz R; Welfle H; Wessner H; Zahn G; Scholz C; Seifert M; Harkins R; Schneider-Mergener J; Höhne W
    J Mol Biol; 2001 Nov; 314(2):293-309. PubMed ID: 11718562
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity.
    Costagliola S; Bonomi M; Morgenthaler NG; Van Durme J; Panneels V; Refetoff S; Vassart G
    Mol Endocrinol; 2004 Dec; 18(12):3020-34. PubMed ID: 15319453
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.