336 related articles for article (PubMed ID: 12913006)
1. Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor.
Jung KM; Tan S; Landman N; Petrova K; Murray S; Lewis R; Kim PK; Kim DS; Ryu SH; Chao MV; Kim TW
J Biol Chem; 2003 Oct; 278(43):42161-9. PubMed ID: 12913006
[TBL] [Abstract][Full Text] [Related]
2. Cleavage of p75 neurotrophin receptor by alpha-secretase and gamma-secretase requires specific receptor domains.
Zampieri N; Xu CF; Neubert TA; Chao MV
J Biol Chem; 2005 Apr; 280(15):14563-71. PubMed ID: 15701642
[TBL] [Abstract][Full Text] [Related]
3. Proteolytic processing of the p75 neurotrophin receptor and two homologs generates C-terminal fragments with signaling capability.
Kanning KC; Hudson M; Amieux PS; Wiley JC; Bothwell M; Schecterson LC
J Neurosci; 2003 Jul; 23(13):5425-36. PubMed ID: 12843241
[TBL] [Abstract][Full Text] [Related]
4. The effects of transmembrane sequence and dimerization on cleavage of the p75 neurotrophin receptor by γ-secretase.
Sykes AM; Palstra N; Abankwa D; Hill JM; Skeldal S; Matusica D; Venkatraman P; Hancock JF; Coulson EJ
J Biol Chem; 2012 Dec; 287(52):43810-24. PubMed ID: 23105112
[TBL] [Abstract][Full Text] [Related]
5. The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments.
LaVoie MJ; Selkoe DJ
J Biol Chem; 2003 Sep; 278(36):34427-37. PubMed ID: 12826675
[TBL] [Abstract][Full Text] [Related]
6. Release of a membrane-bound death domain by gamma-secretase processing of the p75NTR homolog NRADD.
Gowrishankar K; Zeidler MG; Vincenz C
J Cell Sci; 2004 Aug; 117(Pt 18):4099-111. PubMed ID: 15280425
[TBL] [Abstract][Full Text] [Related]
7. Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Abeta-like peptide.
Lammich S; Okochi M; Takeda M; Kaether C; Capell A; Zimmer AK; Edbauer D; Walter J; Steiner H; Haass C
J Biol Chem; 2002 Nov; 277(47):44754-9. PubMed ID: 12223485
[TBL] [Abstract][Full Text] [Related]
8. Presenilin 1 mutations activate gamma 42-secretase but reciprocally inhibit epsilon-secretase cleavage of amyloid precursor protein (APP) and S3-cleavage of notch.
Chen F; Gu Y; Hasegawa H; Ruan X; Arawaka S; Fraser P; Westaway D; Mount H; St George-Hyslop P
J Biol Chem; 2002 Sep; 277(39):36521-6. PubMed ID: 12119298
[TBL] [Abstract][Full Text] [Related]
9. The p75NTR intracellular domain generated by neurotrophin-induced receptor cleavage potentiates Trk signaling.
Ceni C; Kommaddi RP; Thomas R; Vereker E; Liu X; McPherson PS; Ritter B; Barker PA
J Cell Sci; 2010 Jul; 123(Pt 13):2299-307. PubMed ID: 20530577
[TBL] [Abstract][Full Text] [Related]
10. Functional implications of the presenilin dimerization: reconstitution of gamma-secretase activity by assembly of a catalytic site at the dimer interface of two catalytically inactive presenilins.
Cervantes S; Saura CA; Pomares E; Gonzàlez-Duarte R; Marfany G
J Biol Chem; 2004 Aug; 279(35):36519-29. PubMed ID: 15220354
[TBL] [Abstract][Full Text] [Related]
11. TrkA receptor activation by nerve growth factor induces shedding of the p75 neurotrophin receptor followed by endosomal gamma-secretase-mediated release of the p75 intracellular domain.
Urra S; Escudero CA; Ramos P; Lisbona F; Allende E; Covarrubias P; Parraguez JI; Zampieri N; Chao MV; Annaert W; Bronfman FC
J Biol Chem; 2007 Mar; 282(10):7606-15. PubMed ID: 17215246
[TBL] [Abstract][Full Text] [Related]
12. Palmitoylation of the C-terminal fragment of p75(NTR) regulates death signaling and is required for subsequent cleavage by gamma-secretase.
Underwood CK; Reid K; May LM; Bartlett PF; Coulson EJ
Mol Cell Neurosci; 2008 Feb; 37(2):346-58. PubMed ID: 18055214
[TBL] [Abstract][Full Text] [Related]
13. Association between Presenilin-1 and TRAF6 modulates regulated intramembrane proteolysis of the p75NTR neurotrophin receptor.
Powell JC; Twomey C; Jain R; McCarthy JV
J Neurochem; 2009 Jan; 108(1):216-30. PubMed ID: 19012753
[TBL] [Abstract][Full Text] [Related]
14. Notch and the amyloid precursor protein are cleaved by similar gamma-secretase(s).
Kimberly WT; Esler WP; Ye W; Ostaszewski BL; Gao J; Diehl T; Selkoe DJ; Wolfe MS
Biochemistry; 2003 Jan; 42(1):137-44. PubMed ID: 12515548
[TBL] [Abstract][Full Text] [Related]
15. Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch.
Lee SF; Shah S; Li H; Yu C; Han W; Yu G
J Biol Chem; 2002 Nov; 277(47):45013-9. PubMed ID: 12297508
[TBL] [Abstract][Full Text] [Related]
16. Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4.
Lee HJ; Jung KM; Huang YZ; Bennett LB; Lee JS; Mei L; Kim TW
J Biol Chem; 2002 Feb; 277(8):6318-23. PubMed ID: 11741961
[TBL] [Abstract][Full Text] [Related]
17. The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase.
Six E; Ndiaye D; Laabi Y; Brou C; Gupta-Rossi N; Israel A; Logeat F
Proc Natl Acad Sci U S A; 2003 Jun; 100(13):7638-43. PubMed ID: 12794186
[TBL] [Abstract][Full Text] [Related]
18. Gamma-secretase-independent role for cadherin-11 in neurotrophin receptor p75 (p75(NTR)) mediated glioblastoma cell migration.
Berghoff J; Jaisimha AV; Duggan S; MacSharry J; McCarthy JV
Mol Cell Neurosci; 2015 Nov; 69():41-53. PubMed ID: 26476273
[TBL] [Abstract][Full Text] [Related]
19. Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling.
Berezovska O; Jack C; McLean P; Aster JC; Hicks C; Xia W; Wolfe MS; Kimberly WT; Weinmaster G; Selkoe DJ; Hyman BT
J Neurochem; 2000 Aug; 75(2):583-93. PubMed ID: 10899933
[TBL] [Abstract][Full Text] [Related]
20. An intracellular domain fragment of the p75 neurotrophin receptor (p75(NTR)) enhances tropomyosin receptor kinase A (TrkA) receptor function.
Matusica D; Skeldal S; Sykes AM; Palstra N; Sharma A; Coulson EJ
J Biol Chem; 2013 Apr; 288(16):11144-54. PubMed ID: 23471969
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
