These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 12917435)

  • 1. In vivo calpain/caspase cross-talk during 3-nitropropionic acid-induced striatal degeneration: implication of a calpain-mediated cleavage of active caspase-3.
    Bizat N; Hermel JM; Humbert S; Jacquard C; Créminon C; Escartin C; Saudou F; Krajewski S; Hantraye P; Brouillet E
    J Biol Chem; 2003 Oct; 278(44):43245-53. PubMed ID: 12917435
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Calpain is a major cell death effector in selective striatal degeneration induced in vivo by 3-nitropropionate: implications for Huntington's disease.
    Bizat N; Hermel JM; Boyer F; Jacquard C; Créminon C; Ouary S; Escartin C; Hantraye P; Kajewski S; Brouillet E
    J Neurosci; 2003 Jun; 23(12):5020-30. PubMed ID: 12832525
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neuroprotective effect of zVAD against the neurotoxin 3-nitropropionic acid involves inhibition of calpain.
    Bizat N; Galas MC; Jacquard C; Boyer F; Hermel JM; Schiffmann SN; Hantraye P; Blum D; Brouillet E
    Neuropharmacology; 2005 Oct; 49(5):695-702. PubMed ID: 15998526
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel systemically active caspase inhibitor attenuates the toxicities of MPTP, malonate, and 3NP in vivo.
    Yang L; Sugama S; Mischak RP; Kiaei M; Bizat N; Brouillet E; Joh TH; Beal MF
    Neurobiol Dis; 2004 Nov; 17(2):250-9. PubMed ID: 15474362
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Death of cortical and striatal neurons induced by mitochondrial defect involves differential molecular mechanisms.
    Galas MC; Bizat N; Cuvelier L; Bantubungi K; Brouillet E; Schiffmann SN; Blum D
    Neurobiol Dis; 2004 Feb; 15(1):152-9. PubMed ID: 14751780
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Calpain facilitates the neuron death induced by 3-nitropropionic acid and contributes to the necrotic morphology.
    Pang Z; Bondada V; Sengoku T; Siman R; Geddes JW
    J Neuropathol Exp Neurol; 2003 Jun; 62(6):633-43. PubMed ID: 12834108
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Minocycline in phenotypic models of Huntington's disease.
    Bantubungi K; Jacquard C; Greco A; Pintor A; Chtarto A; Tai K; Galas MC; Tenenbaum L; Déglon N; Popoli P; Minghetti L; Brouillet E; Brotchi J; Levivier M; Schiffmann SN; Blum D
    Neurobiol Dis; 2005 Feb; 18(1):206-17. PubMed ID: 15649711
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Influence of cytosolic and mitochondrial Ca2+, ATP, mitochondrial membrane potential, and calpain activity on the mechanism of neuron death induced by 3-nitropropionic acid.
    Nasr P; Gursahani HI; Pang Z; Bondada V; Lee J; Hadley RW; Geddes JW
    Neurochem Int; 2003 Jul; 43(2):89-99. PubMed ID: 12620277
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Calpain and caspase processing of caspase-12 contribute to the ER stress-induced cell death pathway in differentiated PC12 cells.
    Martinez JA; Zhang Z; Svetlov SI; Hayes RL; Wang KK; Larner SF
    Apoptosis; 2010 Dec; 15(12):1480-93. PubMed ID: 20640600
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Memantine reduces striatal cell death with decreasing calpain level in 3-nitropropionic model of Huntington's disease.
    Lee ST; Chu K; Park JE; Kang L; Ko SY; Jung KH; Kim M
    Brain Res; 2006 Nov; 1118(1):199-207. PubMed ID: 16959224
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of calpain and caspase-3 prevented apoptosis and preserved electrophysiological properties of voltage-gated and ligand-gated ion channels in rat primary cortical neurons exposed to glutamate.
    Ray SK; Karmakar S; Nowak MW; Banik NL
    Neuroscience; 2006 May; 139(2):577-95. PubMed ID: 16504408
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF.
    Puerta E; Hervias I; Barros-Miñones L; Jordan J; Ricobaraza A; Cuadrado-Tejedor M; García-Osta A; Aguirre N
    Neurobiol Dis; 2010 May; 38(2):237-45. PubMed ID: 20109548
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synergistic activation of caspase-3 by m-calpain after neonatal hypoxia-ischemia: a mechanism of "pathological apoptosis"?
    Blomgren K; Zhu C; Wang X; Karlsson JO; Leverin AL; Bahr BA; Mallard C; Hagberg H
    J Biol Chem; 2001 Mar; 276(13):10191-8. PubMed ID: 11124942
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Distinct mechanistic roles of calpain and caspase activation in neurodegeneration as revealed in mice overexpressing their specific inhibitors.
    Higuchi M; Tomioka M; Takano J; Shirotani K; Iwata N; Masumoto H; Maki M; Itohara S; Saido TC
    J Biol Chem; 2005 Apr; 280(15):15229-37. PubMed ID: 15699033
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Participation of par-4 in the degeneration of striatal neurons induced by metabolic compromise with 3-nitropropionic acid.
    Duan W; Guo Z; Mattson MP
    Exp Neurol; 2000 Sep; 165(1):1-11. PubMed ID: 10964480
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Calpain-1 cleaves and activates caspase-7.
    Gafni J; Cong X; Chen SF; Gibson BW; Ellerby LM
    J Biol Chem; 2009 Sep; 284(37):25441-9. PubMed ID: 19617626
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of GSK-3beta by calpain in the 3-nitropropionic acid model.
    Crespo-Biel N; Camins A; Gutiérrez-Cuesta J; Melchiorri D; Nicoletti F; Pallàs M; Canudas AM
    Hippocampus; 2010 Aug; 20(8):962-70. PubMed ID: 19714564
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Brain mitochondrial defects amplify intracellular [Ca2+] rise and neurodegeneration but not Ca2+ entry during NMDA receptor activation.
    Jacquard C; Trioulier Y; Cosker F; Escartin C; Bizat N; Hantraye P; Cancela JM; Bonvento G; Brouillet E
    FASEB J; 2006 May; 20(7):1021-3. PubMed ID: 16571773
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Direct cleavage by the calcium-activated protease calpain can lead to inactivation of caspases.
    Chua BT; Guo K; Li P
    J Biol Chem; 2000 Feb; 275(7):5131-5. PubMed ID: 10671558
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex.
    Twiddy D; Brown DG; Adrain C; Jukes R; Martin SJ; Cohen GM; MacFarlane M; Cain K
    J Biol Chem; 2004 May; 279(19):19665-82. PubMed ID: 14993223
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.