179 related articles for article (PubMed ID: 12917444)
1. Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons.
Roucou X; Guo Q; Zhang Y; Goodyer CG; LeBlanc AC
J Biol Chem; 2003 Oct; 278(42):40877-81. PubMed ID: 12917444
[TBL] [Abstract][Full Text] [Related]
2. Cytosolic prion protein (PrP) is not toxic in N2a cells and primary neurons expressing pathogenic PrP mutations.
Fioriti L; Dossena S; Stewart LR; Stewart RS; Harris DA; Forloni G; Chiesa R
J Biol Chem; 2005 Mar; 280(12):11320-8. PubMed ID: 15632159
[TBL] [Abstract][Full Text] [Related]
3. Cytosolic prion protein is the predominant anti-Bax prion protein form: exclusion of transmembrane and secreted prion protein forms in the anti-Bax function.
Lin DT; Jodoin J; Baril M; Goodyer CG; Leblanc AC
Biochim Biophys Acta; 2008 Oct; 1783(10):2001-12. PubMed ID: 18590778
[TBL] [Abstract][Full Text] [Related]
4. Mammalian prion protein suppresses Bax-induced cell death in yeast.
Li A; Harris DA
J Biol Chem; 2005 Apr; 280(17):17430-4. PubMed ID: 15753097
[TBL] [Abstract][Full Text] [Related]
5. Prion protein protects human neurons against Bax-mediated apoptosis.
Bounhar Y; Zhang Y; Goodyer CG; LeBlanc A
J Biol Chem; 2001 Oct; 276(42):39145-9. PubMed ID: 11522774
[TBL] [Abstract][Full Text] [Related]
6. The C-terminal globular domain of the prion protein is necessary and sufficient for import into the endoplasmic reticulum.
Heske J; Heller U; Winklhofer KF; Tatzelt J
J Biol Chem; 2004 Feb; 279(7):5435-43. PubMed ID: 14645231
[TBL] [Abstract][Full Text] [Related]
7. Calpain and other cytosolic proteases can contribute to the degradation of retro-translocated prion protein in the cytosol.
Wang X; Wang F; Sy MS; Ma J
J Biol Chem; 2005 Jan; 280(1):317-25. PubMed ID: 15525638
[TBL] [Abstract][Full Text] [Related]
8. The retention of prion protein in the endoplasmic reticulum prevents N2A cells from proteasome inhibition-induced cytotoxicity.
Fang S; Wang R; Liu H; Zhuang W; Wang Z; Zhang J; Pei L; Liu Y; Su Y
Biochem Biophys Res Commun; 2017 Sep; 491(2):500-507. PubMed ID: 28669732
[TBL] [Abstract][Full Text] [Related]
9. Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol.
Ma J; Wollmann R; Lindquist S
Science; 2002 Nov; 298(5599):1781-5. PubMed ID: 12386337
[TBL] [Abstract][Full Text] [Related]
10. Cytosolic prion protein toxicity is independent of cellular prion protein expression and prion propagation.
Norstrom EM; Ciaccio MF; Rassbach B; Wollmann R; Mastrianni JA
J Virol; 2007 Mar; 81(6):2831-7. PubMed ID: 17182694
[TBL] [Abstract][Full Text] [Related]
11. Reticulon 3 attenuates the clearance of cytosolic prion aggregates via inhibiting autophagy.
Chen R; Jin R; Wu L; Ye X; Yang Y; Luo K; Wang W; Wu D; Ye X; Huang L; Huang T; Xiao G
Autophagy; 2011 Feb; 7(2):205-16. PubMed ID: 21119307
[TBL] [Abstract][Full Text] [Related]
12. Protein misfolding cyclic amplification induces the conversion of recombinant prion protein to PrP oligomers causing neuronal apoptosis.
Yuan Z; Yang L; Chen B; Zhu T; Hassan MF; Yin X; Zhou X; Zhao D
J Neurochem; 2015 Jun; 133(5):722-9. PubMed ID: 25810062
[TBL] [Abstract][Full Text] [Related]
13. Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation.
Drisaldi B; Stewart RS; Adles C; Stewart LR; Quaglio E; Biasini E; Fioriti L; Chiesa R; Harris DA
J Biol Chem; 2003 Jun; 278(24):21732-43. PubMed ID: 12663673
[TBL] [Abstract][Full Text] [Related]
14. Familial prion protein mutants inhibit Hrd1-mediated retrotranslocation of misfolded proteins by depleting misfolded protein sensor BiP.
Peters SL; Déry MA; LeBlanc AC
Hum Mol Genet; 2016 Mar; 25(5):976-88. PubMed ID: 26740554
[TBL] [Abstract][Full Text] [Related]
15. Activation of Prn-p gene and stable transfection of Prn-p cDNA in leukemia MEL and neuroblastoma N2a cells increased production of PrP(C) but not prevented DNA fragmentation initiated by serum deprivation.
Gougoumas DD; Vizirianakis IS; Triviai IN; Tsiftsoglou AS
J Cell Physiol; 2007 May; 211(2):551-9. PubMed ID: 17186498
[TBL] [Abstract][Full Text] [Related]
16. Defective retrotranslocation causes loss of anti-Bax function in human familial prion protein mutants.
Jodoin J; Laroche-Pierre S; Goodyer CG; LeBlanc AC
J Neurosci; 2007 May; 27(19):5081-91. PubMed ID: 17494694
[TBL] [Abstract][Full Text] [Related]
17. Mutational analysis of topological determinants in prion protein (PrP) and measurement of transmembrane and cytosolic PrP during prion infection.
Stewart RS; Harris DA
J Biol Chem; 2003 Nov; 278(46):45960-8. PubMed ID: 12933795
[TBL] [Abstract][Full Text] [Related]
18. Proteasome inhibitors promote the sequestration of PrPSc into aggresomes within the cytosol of prion-infected CAD neuronal cells.
Dron M; Dandoy-Dron F; Farooq Salamat MK; Laude H
J Gen Virol; 2009 Aug; 90(Pt 8):2050-2060. PubMed ID: 19339478
[TBL] [Abstract][Full Text] [Related]
19. Heat shock protein 70 selectively mediates the degradation of cytosolic PrPs and restores the cytosolic PrP-induced cytotoxicity via a molecular interaction.
Zhang J; Wang K; Guo Y; Shi Q; Tian C; Chen C; Gao C; Zhang BY; Dong XP
Virol J; 2012 Dec; 9():303. PubMed ID: 23216755
[TBL] [Abstract][Full Text] [Related]
20. Expression of mutant or cytosolic PrP in transgenic mice and cells is not associated with endoplasmic reticulum stress or proteasome dysfunction.
Quaglio E; Restelli E; Garofoli A; Dossena S; De Luigi A; Tagliavacca L; Imperiale D; Migheli A; Salmona M; Sitia R; Forloni G; Chiesa R
PLoS One; 2011 Apr; 6(4):e19339. PubMed ID: 21559407
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]