606 related articles for article (PubMed ID: 12923173)
1. Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity.
Guo GL; Lambert G; Negishi M; Ward JM; Brewer HB; Kliewer SA; Gonzalez FJ; Sinal CJ
J Biol Chem; 2003 Nov; 278(46):45062-71. PubMed ID: 12923173
[TBL] [Abstract][Full Text] [Related]
2. The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.
Zhang J; Huang W; Qatanani M; Evans RM; Moore DD
J Biol Chem; 2004 Nov; 279(47):49517-22. PubMed ID: 15358766
[TBL] [Abstract][Full Text] [Related]
3. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
Wagner M; Halilbasic E; Marschall HU; Zollner G; Fickert P; Langner C; Zatloukal K; Denk H; Trauner M
Hepatology; 2005 Aug; 42(2):420-30. PubMed ID: 15986414
[TBL] [Abstract][Full Text] [Related]
4. Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor.
Kast HR; Goodwin B; Tarr PT; Jones SA; Anisfeld AM; Stoltz CM; Tontonoz P; Kliewer S; Willson TM; Edwards PA
J Biol Chem; 2002 Jan; 277(4):2908-15. PubMed ID: 11706036
[TBL] [Abstract][Full Text] [Related]
5. Regulation of CYP3A4 by the bile acid receptor FXR: evidence for functional binding sites in the CYP3A4 gene.
Gnerre C; Blättler S; Kaufmann MR; Looser R; Meyer UA
Pharmacogenetics; 2004 Oct; 14(10):635-45. PubMed ID: 15454728
[TBL] [Abstract][Full Text] [Related]
6. Regulation of drug transporter gene expression by nuclear receptors.
Staudinger JL; Madan A; Carol KM; Parkinson A
Drug Metab Dispos; 2003 May; 31(5):523-7. PubMed ID: 12695338
[TBL] [Abstract][Full Text] [Related]
7. Protective role of hydroxysteroid sulfotransferase in lithocholic acid-induced liver toxicity.
Kitada H; Miyata M; Nakamura T; Tozawa A; Honma W; Shimada M; Nagata K; Sinal CJ; Guo GL; Gonzalez FJ; Yamazoe Y
J Biol Chem; 2003 May; 278(20):17838-44. PubMed ID: 12637555
[TBL] [Abstract][Full Text] [Related]
8. Pregnane X receptor is a target of farnesoid X receptor.
Jung D; Mangelsdorf DJ; Meyer UA
J Biol Chem; 2006 Jul; 281(28):19081-91. PubMed ID: 16682417
[TBL] [Abstract][Full Text] [Related]
9. Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice.
Saini SP; Mu Y; Gong H; Toma D; Uppal H; Ren S; Li S; Poloyac SM; Xie W
Hepatology; 2005 Mar; 41(3):497-505. PubMed ID: 15726644
[TBL] [Abstract][Full Text] [Related]
10. Master regulation of bile acid and xenobiotic metabolism via the FXR, PXR and CAR trio.
Modica S; Bellafante E; Moschetta A
Front Biosci (Landmark Ed); 2009 Jan; 14(12):4719-45. PubMed ID: 19273385
[TBL] [Abstract][Full Text] [Related]
11. Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR.
Handschin C; Meyer UA
Arch Biochem Biophys; 2005 Jan; 433(2):387-96. PubMed ID: 15581595
[TBL] [Abstract][Full Text] [Related]
12. Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha. Functional implications in hepatic cholesterol and glucose metabolism.
Bhalla S; Ozalp C; Fang S; Xiang L; Kemper JK
J Biol Chem; 2004 Oct; 279(43):45139-47. PubMed ID: 15322103
[TBL] [Abstract][Full Text] [Related]
13. Coordinated roles of pregnane X receptor and constitutive androstane receptor in autoinduction of voriconazole metabolism in mice.
Ohbuchi M; Yoshinari K; Kaneko H; Matsumoto S; Inoue A; Kawamura A; Usui T; Yamazoe Y
Antimicrob Agents Chemother; 2013 Mar; 57(3):1332-8. PubMed ID: 23274663
[TBL] [Abstract][Full Text] [Related]
14. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.
Xie W; Radominska-Pandya A; Shi Y; Simon CM; Nelson MC; Ong ES; Waxman DJ; Evans RM
Proc Natl Acad Sci U S A; 2001 Mar; 98(6):3375-80. PubMed ID: 11248086
[TBL] [Abstract][Full Text] [Related]
15. Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.
Zollner G; Wagner M; Moustafa T; Fickert P; Silbert D; Gumhold J; Fuchsbichler A; Halilbasic E; Denk H; Marschall HU; Trauner M
Am J Physiol Gastrointest Liver Physiol; 2006 May; 290(5):G923-32. PubMed ID: 16357057
[TBL] [Abstract][Full Text] [Related]
16. Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis.
Teng S; Piquette-Miller M
Br J Pharmacol; 2007 Jun; 151(3):367-76. PubMed ID: 17435798
[TBL] [Abstract][Full Text] [Related]
17. Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury.
Stedman CA; Liddle C; Coulter SA; Sonoda J; Alvarez JG; Moore DD; Evans RM; Downes M
Proc Natl Acad Sci U S A; 2005 Feb; 102(6):2063-8. PubMed ID: 15684063
[TBL] [Abstract][Full Text] [Related]
18. Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor.
Staudinger J; Liu Y; Madan A; Habeebu S; Klaassen CD
Drug Metab Dispos; 2001 Nov; 29(11):1467-72. PubMed ID: 11602523
[TBL] [Abstract][Full Text] [Related]
19. Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor.
Kliewer SA; Willson TM
J Lipid Res; 2002 Mar; 43(3):359-64. PubMed ID: 11893771
[TBL] [Abstract][Full Text] [Related]
20. Compensatory induction of liver efflux transporters in response to ANIT-induced liver injury is impaired in FXR-null mice.
Cui YJ; Aleksunes LM; Tanaka Y; Goedken MJ; Klaassen CD
Toxicol Sci; 2009 Jul; 110(1):47-60. PubMed ID: 19407337
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]