BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 12927779)

  • 1. Bioinformatics of granzymes: sequence comparison and structural studies on granzyme family by homology modeling.
    Sattar R; Ali SA; Abbasi A
    Biochem Biophys Res Commun; 2003 Sep; 308(4):726-35. PubMed ID: 12927779
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors.
    Kam CM; Hudig D; Powers JC
    Biochim Biophys Acta; 2000 Mar; 1477(1-2):307-23. PubMed ID: 10708866
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins.
    Odake S; Kam CM; Narasimhan L; Poe M; Blake JT; Krahenbuhl O; Tschopp J; Powers JC
    Biochemistry; 1991 Feb; 30(8):2217-27. PubMed ID: 1998680
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The three-dimensional structure of human granzyme B compared to caspase-3, key mediators of cell death with cleavage specificity for aspartic acid in P1.
    Rotonda J; Garcia-Calvo M; Bull HG; Geissler WM; McKeever BM; Willoughby CA; Thornberry NA; Becker JW
    Chem Biol; 2001 Apr; 8(4):357-68. PubMed ID: 11325591
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features.
    Hink-Schauer C; Estébanez-Perpiñá E; Wilharm E; Fuentes-Prior P; Klinkert W; Bode W; Jenne DE
    J Biol Chem; 2002 Dec; 277(52):50923-33. PubMed ID: 12384499
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Granzymes: a variety of serine protease specificities encoded by genetically distinct subfamilies.
    Smyth MJ; O'Connor MD; Trapani JA
    J Leukoc Biol; 1996 Nov; 60(5):555-62. PubMed ID: 8929545
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue.
    Estébanez-Perpiña E; Fuentes-Prior P; Belorgey D; Braun M; Kiefersauer R; Maskos K; Huber R; Rubin H; Bode W
    Biol Chem; 2000 Dec; 381(12):1203-14. PubMed ID: 11209755
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and evaluation of diphenyl phosphonate esters as inhibitors of the trypsin-like granzymes A and K and mast cell tryptase.
    Jackson DS; Fraser SA; Ni LM; Kam CM; Winkler U; Johnson DA; Froelich CJ; Hudig D; Powers JC
    J Med Chem; 1998 Jun; 41(13):2289-301. PubMed ID: 9632362
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Importance of the P4' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop.
    Sun J; Whisstock JC; Harriott P; Walker B; Novak A; Thompson PE; Smith AI; Bird PI
    J Biol Chem; 2001 May; 276(18):15177-84. PubMed ID: 11278311
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Residual cytotoxicity and granzyme K expression in granzyme A-deficient cytotoxic lymphocytes.
    Shresta S; Goda P; Wesselschmidt R; Ley TJ
    J Biol Chem; 1997 Aug; 272(32):20236-44. PubMed ID: 9242702
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A family of serine esterases in lytic granules of cytolytic T lymphocytes.
    Masson D; Tschopp J
    Cell; 1987 Jun; 49(5):679-85. PubMed ID: 3555842
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Granzymes: a family of lymphocyte granule serine proteases.
    Trapani JA
    Genome Biol; 2001; 2(12):REVIEWS3014. PubMed ID: 11790262
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Subsite specificities of granzyme M: a study of inhibitors and newly synthesized thiobenzyl ester substrates.
    Rukamp BJ; Kam CM; Natarajan S; Bolton BW; Smyth MJ; Kelly JM; Powers JC
    Arch Biochem Biophys; 2004 Feb; 422(1):9-22. PubMed ID: 14725853
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of structural determinants of granzyme B reveals potent mediators of extended substrate specificity.
    Ruggles SW; Fletterick RJ; Craik CS
    J Biol Chem; 2004 Jul; 279(29):30751-9. PubMed ID: 15123647
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evidence for the existence of granzyme-like serine proteases in teleost cytotoxic cells.
    Praveen K; Evans DL; Jaso-Friedmann L
    J Mol Evol; 2004 Apr; 58(4):449-59. PubMed ID: 15114423
    [TBL] [Abstract][Full Text] [Related]  

  • 16. P-4 and RNKP-7, new granzyme-like serine proteases expressed in activated rat lymphocytes.
    Ewoldt GR; Smyth MJ; Darcy PK; Harris JL; Craik CS; Horowitz B; Woodard SL; Powers JC; Hudig D
    J Immunol; 1997 May; 158(10):4574-83. PubMed ID: 9144469
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of {alpha}-tubulin as a granzyme B substrate during CTL-mediated apoptosis.
    Goping IS; Sawchuk T; Underhill DA; Bleackley RC
    J Cell Sci; 2006 Mar; 119(Pt 5):858-65. PubMed ID: 16495481
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The peptide loop consisting of amino acids 139-157 of human granzyme B (fragmentin 2) contains an immunodominant epitope recognized by the mouse.
    Apostolidis VA; Browne KA; Smyth MJ; Trapani JA
    Mol Immunol; 1995 Aug; 32(12):909-17. PubMed ID: 7565817
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Granzyme M is a regulatory protease that inactivates proteinase inhibitor 9, an endogenous inhibitor of granzyme B.
    Mahrus S; Kisiel W; Craik CS
    J Biol Chem; 2004 Dec; 279(52):54275-82. PubMed ID: 15494398
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Granzyme M: characterization with sites of post-translational modification and specific sites of interaction with substrates and inhibitors.
    Khurshid R; Saleem M; Akhtar MS; Salim A
    Mol Biol Rep; 2011 Jun; 38(5):2953-60. PubMed ID: 20107908
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.