470 related articles for article (PubMed ID: 12931192)
1. Artemisinins target the SERCA of Plasmodium falciparum.
Eckstein-Ludwig U; Webb RJ; Van Goethem ID; East JM; Lee AG; Kimura M; O'Neill PM; Bray PG; Ward SA; Krishna S
Nature; 2003 Aug; 424(6951):957-61. PubMed ID: 12931192
[TBL] [Abstract][Full Text] [Related]
2. Malaria: to kill a parasite.
Ridley RG
Nature; 2003 Aug; 424(6951):887-9. PubMed ID: 12931167
[No Abstract] [Full Text] [Related]
3. A single amino acid residue can determine the sensitivity of SERCAs to artemisinins.
Uhlemann AC; Cameron A; Eckstein-Ludwig U; Fischbarg J; Iserovich P; Zuniga FA; East M; Lee A; Brady L; Haynes RK; Krishna S
Nat Struct Mol Biol; 2005 Jul; 12(7):628-9. PubMed ID: 15937493
[TBL] [Abstract][Full Text] [Related]
4. Pumped up: reflections on PfATP6 as the target for artemisinins.
Krishna S; Pulcini S; Moore CM; Teo BH; Staines HM
Trends Pharmacol Sci; 2014 Jan; 35(1):4-11. PubMed ID: 24268763
[TBL] [Abstract][Full Text] [Related]
5. The Fe2+-mediated decomposition, PfATP6 binding, and antimalarial activities of artemisone and other artemisinins: the unlikelihood of C-centered radicals as bioactive intermediates.
Haynes RK; Chan WC; Lung CM; Uhlemann AC; Eckstein U; Taramelli D; Parapini S; Monti D; Krishna S
ChemMedChem; 2007 Oct; 2(10):1480-97. PubMed ID: 17768732
[TBL] [Abstract][Full Text] [Related]
6. The Plasmodium falciparum Ca(2+)-ATPase PfATP6: insensitive to artemisinin, but a potential drug target.
Arnou B; Montigny C; Morth JP; Nissen P; Jaxel C; Møller JV; Maire Ml
Biochem Soc Trans; 2011 Jun; 39(3):823-31. PubMed ID: 21599655
[TBL] [Abstract][Full Text] [Related]
7. Purified E255L mutant SERCA1a and purified PfATP6 are sensitive to SERCA-type inhibitors but insensitive to artemisinins.
Cardi D; Pozza A; Arnou B; Marchal E; Clausen JD; Andersen JP; Krishna S; Møller JV; le Maire M; Jaxel C
J Biol Chem; 2010 Aug; 285(34):26406-16. PubMed ID: 20530490
[TBL] [Abstract][Full Text] [Related]
8. Artemisinins: mechanisms of action and potential for resistance.
Krishna S; Uhlemann AC; Haynes RK
Drug Resist Updat; 2004; 7(4-5):233-44. PubMed ID: 15533761
[TBL] [Abstract][Full Text] [Related]
9. Investigations into the role of the Plasmodium falciparum SERCA (PfATP6) L263E mutation in artemisinin action and resistance.
Valderramos SG; Scanfeld D; Uhlemann AC; Fidock DA; Krishna S
Antimicrob Agents Chemother; 2010 Sep; 54(9):3842-52. PubMed ID: 20566762
[TBL] [Abstract][Full Text] [Related]
10. Mechanism of antimalarial action of the synthetic trioxolane RBX11160 (OZ277).
Uhlemann AC; Wittlin S; Matile H; Bustamante LY; Krishna S
Antimicrob Agents Chemother; 2007 Feb; 51(2):667-72. PubMed ID: 17145800
[TBL] [Abstract][Full Text] [Related]
11. Expression in yeast links field polymorphisms in PfATP6 to in vitro artemisinin resistance and identifies new inhibitor classes.
Pulcini S; Staines HM; Pittman JK; Slavic K; Doerig C; Halbert J; Tewari R; Shah F; Avery MA; Haynes RK; Krishna S
J Infect Dis; 2013 Aug; 208(3):468-78. PubMed ID: 23599312
[TBL] [Abstract][Full Text] [Related]
12. Enantiomeric 1,2,4-trioxanes display equivalent in vitro antimalarial activity versus Plasmodium falciparum malaria parasites: implications for the molecular mechanism of action of the artemisinins.
O'Neill PM; Rawe SL; Borstnik K; Miller A; Ward SA; Bray PG; Davies J; Oh CH; Posner GH
Chembiochem; 2005 Nov; 6(11):2048-54. PubMed ID: 16222725
[TBL] [Abstract][Full Text] [Related]
13. Structure-based drug design studies of the interactions of ent-kaurane diterpenes derived from Wedelia paludosa with the Plasmodium falciparum sarco/endoplasmic reticulum Ca²⁺-ATPase PfATP6.
Guimarães DS; Fonseca AL; Batista R; Comar Junior M; Oliveira AB; Taranto AG; Varotti Fde P
Mem Inst Oswaldo Cruz; 2015 Apr; 110(2):255-8. PubMed ID: 25946251
[TBL] [Abstract][Full Text] [Related]
14. Malaria and iron: history and review.
Weinberg ED; Moon J
Drug Metab Rev; 2009; 41(4):644-62. PubMed ID: 19764831
[TBL] [Abstract][Full Text] [Related]
15. Antimalarial activity of artemisinins: identification of a novel target?
Mercereau-Puijalon O; Fandeur T
Lancet; 2003 Dec; 362(9401):2035-6. PubMed ID: 14697798
[No Abstract] [Full Text] [Related]
16. Diversity of the sarco/endoplasmic reticulum Ca(2+)-ATPase orthologue of Plasmodium falciparum (PfATP6).
Dahlström S; Veiga MI; Ferreira P; Mårtensson A; Kaneko A; Andersson B; Björkman A; Gil JP
Infect Genet Evol; 2008 May; 8(3):340-5. PubMed ID: 18359278
[TBL] [Abstract][Full Text] [Related]
17. Current perspectives on the mechanism of action of artemisinins.
Golenser J; Waknine JH; Krugliak M; Hunt NH; Grau GE
Int J Parasitol; 2006 Dec; 36(14):1427-41. PubMed ID: 17005183
[TBL] [Abstract][Full Text] [Related]
18. The binding modes and binding affinities of artemisinin derivatives with Plasmodium falciparum Ca2+-ATPase (PfATP6).
Naik PK; Srivastava M; Bajaj P; Jain S; Dubey A; Ranjan P; Kumar R; Singh H
J Mol Model; 2011 Feb; 17(2):333-57. PubMed ID: 20461426
[TBL] [Abstract][Full Text] [Related]
19. Three-dimensional structure of Plasmodium falciparum Ca2+ -ATPase(PfATP6) and docking of artemisinin derivatives to PfATP6.
Jung M; Kim H; Nam KY; No KT
Bioorg Med Chem Lett; 2005 Jun; 15(12):2994-7. PubMed ID: 15908211
[TBL] [Abstract][Full Text] [Related]
20. Antimalarial screening via large-scale purification of Plasmodium falciparum Ca2+-ATPase 6 and in vitro studies.
David-Bosne S; Florent I; Lund-Winther AM; Hansen JB; Buch-Pedersen M; Machillot P; le Maire M; Jaxel C
FEBS J; 2013 Nov; 280(21):5419-29. PubMed ID: 23497141
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
