BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 12937169)

  • 1. Thermodynamic description of the effect of the mutation Y49F on human glutathione transferase P1-1 in binding with glutathione and the inhibitor S-hexylglutathione.
    Ortiz-Salmerón E; Nuccetelli M; Oakley AJ; Parker MW; Lo Bello M; García-Fuentes L
    J Biol Chem; 2003 Nov; 278(47):46938-48. PubMed ID: 12937169
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Thermodynamic analysis of the binding of glutathione to glutathione S-transferase over a range of temperatures.
    Ortiz-Salmerón E; Yassin Z; Clemente-Jimenez MJ; Las Heras-Vazquez FJ; Rodriguez-Vico F; Barón C; García-Fuentes L
    Eur J Biochem; 2001 Aug; 268(15):4307-14. PubMed ID: 11488926
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystallographic and thermodynamic analysis of the binding of S-octylglutathione to the Tyr 7 to Phe mutant of glutathione S-transferase from Schistosoma japonicum.
    Andújar-Sánchez M; Smith AW; Clemente-Jimenez JM; Rodriguez-Vico F; Las Heras-Vazquez FJ; Jara-Pérez V; Cámara-Artigas A
    Biochemistry; 2005 Feb; 44(4):1174-83. PubMed ID: 15667211
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tertiary interactions stabilise the C-terminal region of human glutathione transferase A1-1: a crystallographic and calorimetric study.
    Kuhnert DC; Sayed Y; Mosebi S; Sayed M; Sewell T; Dirr HW
    J Mol Biol; 2005 Jun; 349(4):825-38. PubMed ID: 15893769
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A calorimetric study of the binding of S-alkylglutathiones to glutathione S-transferase.
    Ortiz-Salmerón E; Yassin Z; Clemente-Jimenez MJ; Las Heras-Vazquez FJ; Rodriguez-Vico F; Barón C; García-Fuentes L
    Biochim Biophys Acta; 2001 Jul; 1548(1):106-13. PubMed ID: 11451443
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of mutation Y6F on the binding properties of Schistosoma japonicum glutathione S-transferase.
    Yassin Z; Ortiz-Salmerón E; Clemente-Jiménez MJ; Barón C; García-Fuentes L
    Int J Biol Macromol; 2003 Sep; 32(3-5):67-75. PubMed ID: 12957302
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Proton release upon glutathione binding to glutathione transferase P1-1: kinetic analysis of a multistep glutathione binding process.
    Caccuri AM; Lo Bello M; Nuccetelli M; Nicotra M; Rossi P; Antonini G; Federici G; Ricci G
    Biochemistry; 1998 Mar; 37(9):3028-34. PubMed ID: 9485455
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glutathione S-transferase Pi has at least three distinguishable xenobiotic substrate sites close to its glutathione-binding site.
    Ralat LA; Colman RF
    J Biol Chem; 2004 Nov; 279(48):50204-13. PubMed ID: 15347687
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Energetics of Glutathione Binding to Human Eukaryotic Elongation Factor 1 Gamma: Isothermal Titration Calorimetry and Molecular Dynamics Studies.
    Tshabalala TN; Tomescu MS; Prior A; Balakrishnan V; Sayed Y; Dirr HW; Achilonu I
    Protein J; 2016 Dec; 35(6):448-458. PubMed ID: 27844275
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Arginine 15 stabilizes an S(N)Ar reaction transition state and the binding of anionic ligands at the active site of human glutathione transferase A1-1.
    Gildenhuys S; Dobreva M; Kinsley N; Sayed Y; Burke J; Pelly S; Gordon GP; Sayed M; Sewell T; Dirr HW
    Biophys Chem; 2010 Feb; 146(2-3):118-25. PubMed ID: 19959275
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Implications of the ligandin binding site on the binding of non-substrate ligands to Schistosoma japonicum-glutathione transferase.
    Yassin Z; Ortiz-Salmerón E; García-Maroto F; Barón C; García-Fuentes L
    Biochim Biophys Acta; 2004 May; 1698(2):227-37. PubMed ID: 15134656
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Energetics of ligand binding to human glutathione transferase A1-1: Tyr-9 associated localisation of the C-terminal helix is ligand-dependent.
    Balchin D; Dirr HW; Sayed Y
    Biophys Chem; 2011 Jul; 156(2-3):153-8. PubMed ID: 21530062
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of bromosulphophthalein binding to human glutathione S-transferase A1-1: thermodynamics and inhibition kinetics.
    Kolobe D; Sayed Y; Dirr HW
    Biochem J; 2004 Sep; 382(Pt 2):703-9. PubMed ID: 15147239
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Calorimetric studies of ligands binding to glutathione S-transferase from the malarial parasite Plasmodium falciparum.
    Quesada-Soriano I; Barón C; García-Maroto F; Aguilera AM; García-Fuentes L
    Biochemistry; 2013 Mar; 52(11):1980-9. PubMed ID: 23439010
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The C-terminus of glutathione S-transferase A1-1 is required for entropically-driven ligand binding.
    Nieslanik BS; Ibarra C; Atkins WM
    Biochemistry; 2001 Mar; 40(12):3536-43. PubMed ID: 11297419
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutations of Gly to Ala in human glutathione transferase P1-1 affect helix 2 (G-site) and induce positive cooperativity in the binding of glutathione.
    Lo Bello M; Nuccetelli M; Chiessi E; Lahm A; Mazzetti AP; Battistoni A; Caccuri AM; Oakley AJ; Parker MW; Tramontano A; Federici G; Ricci G
    J Mol Biol; 1998 Dec; 284(5):1717-25. PubMed ID: 9878382
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Plasmodium falciparum glutathione S-transferase--structural and mechanistic studies on ligand binding and enzyme inhibition.
    Hiller N; Fritz-Wolf K; Deponte M; Wende W; Zimmermann H; Becker K
    Protein Sci; 2006 Feb; 15(2):281-9. PubMed ID: 16385005
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thermodynamics of the ligandin function of human class Alpha glutathione transferase A1-1: energetics of organic anion ligand binding.
    Sayed Y; Hornby JA; Lopez M; Dirr H
    Biochem J; 2002 Apr; 363(Pt 2):341-6. PubMed ID: 11931663
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thermodynamics of glutathione binding to the tyrosine 7 to phenylalanine mutant of glutathione S-transferase from Schistosoma japonicum.
    Andújar-Sánchez M; Clemente-Jiménez JM; Las Heras-Vázquez FJ; Rodríguez-Vico F; Cámara-Artigas A; Jara-Pérez V
    Int J Biol Macromol; 2003 Sep; 32(3-5):77-82. PubMed ID: 12957303
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Site-directed mutagenesis of amino acid residues involved in the glutathione binding of human glutathione S-transferase P1-1.
    Kong KH; Inoue H; Takahashi K
    J Biochem; 1992 Dec; 112(6):725-8. PubMed ID: 1295879
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.