BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 12939297)

  • 1. Regulatory role of cAMP on expression of Cdk4 and p27(Kip1) by inhibiting phosphatidylinositol 3-kinase in corneal endothelial cells.
    Lee HT; Kay EP
    Invest Ophthalmol Vis Sci; 2003 Sep; 44(9):3816-25. PubMed ID: 12939297
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulatory role of PI 3-kinase on expression of Cdk4 and p27, nuclear localization of Cdk4, and phosphorylation of p27 in corneal endothelial cells.
    Lee HT; Kay EP
    Invest Ophthalmol Vis Sci; 2003 Apr; 44(4):1521-8. PubMed ID: 12657588
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cdk4 and p27Kip1 play a role in PLC-gamma1-mediated mitogenic signaling pathway of 18 kDa FGF-2 in corneal endothelial cells.
    Lee HT; Kim TY; Kay EP
    Mol Vis; 2002 Feb; 8():17-25. PubMed ID: 11889462
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of p27(Kip1) in cAMP- and TGF-beta2-mediated antiproliferation in rabbit corneal endothelial cells.
    Kim TY; Kim WI; Smith RE; Kay ED
    Invest Ophthalmol Vis Sci; 2001 Dec; 42(13):3142-9. PubMed ID: 11726615
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential activity of TGF-beta2 on the expression of p27Kip1 and Cdk4 in actively cycling and contact inhibited rabbit corneal endothelial cells.
    Kim TY; Kim WI; Smith RE; Kay EP
    Mol Vis; 2001 Nov; 7():261-70. PubMed ID: 11723444
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transforming growth factor beta(1) selectively inhibits the cyclic AMP-dependent proliferation of primary thyroid epithelial cells by preventing the association of cyclin D3-cdk4 with nuclear p27(kip1).
    Depoortere F; Pirson I; Bartek J; Dumont JE; Roger PP
    Mol Biol Cell; 2000 Mar; 11(3):1061-76. PubMed ID: 10712520
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.
    Lenferink AE; Busse D; Flanagan WM; Yakes FM; Arteaga CL
    Cancer Res; 2001 Sep; 61(17):6583-91. PubMed ID: 11522658
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PI 3-kinase/Rac1 and ERK1/2 regulate FGF-2-mediated cell proliferation through phosphorylation of p27 at Ser10 by KIS and at Thr187 by Cdc25A/Cdk2.
    Lee JG; Kay EP
    Invest Ophthalmol Vis Sci; 2011 Jan; 52(1):417-26. PubMed ID: 20811053
    [TBL] [Abstract][Full Text] [Related]  

  • 9. FGF-2 induced reorganization and disruption of actin cytoskeleton through PI 3-kinase, Rho, and Cdc42 in corneal endothelial cells.
    Lee HT; Kay EP
    Mol Vis; 2003 Dec; 9():624-34. PubMed ID: 14685150
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human corneal endothelial cells employ phosphorylation of p27(Kip1) at both Ser10 and Thr187 sites for FGF-2-mediated cell proliferation via PI 3-kinase.
    Lee JG; Song JS; Smith RE; Kay EP
    Invest Ophthalmol Vis Sci; 2011 Oct; 52(11):8216-23. PubMed ID: 21948550
    [TBL] [Abstract][Full Text] [Related]  

  • 11. cAMP-mediated growth inhibition of lymphoid cells in G1: rapid down-regulation of cyclin D3 at the level of translation.
    Naderi S; Gützkow KB; Christoffersen J; Smeland EB; Blomhoff HK
    Eur J Immunol; 2000 Jun; 30(6):1757-68. PubMed ID: 10898514
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer.
    Viglietto G; Motti ML; Bruni P; Melillo RM; D'Alessio A; Califano D; Vinci F; Chiappetta G; Tsichlis P; Bellacosa A; Fusco A; Santoro M
    Nat Med; 2002 Oct; 8(10):1136-44. PubMed ID: 12244303
    [TBL] [Abstract][Full Text] [Related]  

  • 13. EGF stimulates mesangial cell mitogenesis via PI3-kinase-mediated MAPK-dependent and AKT kinase-independent manner: involvement of c-fos and p27Kip1.
    Mahimainathan L; Ghosh-Choudhury N; Venkatesan BA; Danda RS; Choudhury GG
    Am J Physiol Renal Physiol; 2005 Jul; 289(1):F72-82. PubMed ID: 15701816
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action.
    Yakes FM; Chinratanalab W; Ritter CA; King W; Seelig S; Arteaga CL
    Cancer Res; 2002 Jul; 62(14):4132-41. PubMed ID: 12124352
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The cyclin D3-CDK4-p27kip1 holoenzyme in thyroid epithelial cells: activation by TSH, inhibition by TGFbeta, and phosphorylations of its subunits demonstrated by two-dimensional gel electrophoresis.
    Coulonval K; Bockstaele L; Paternot S; Dumont JE; Roger PP
    Exp Cell Res; 2003 Nov; 291(1):135-49. PubMed ID: 14597415
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization.
    Shin I; Yakes FM; Rojo F; Shin NY; Bakin AV; Baselga J; Arteaga CL
    Nat Med; 2002 Oct; 8(10):1145-52. PubMed ID: 12244301
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The phosphoinositide 3-kinase/Akt pathway regulates cell cycle progression of HL60 human leukemia cells through cytoplasmic relocalization of the cyclin-dependent kinase inhibitor p27(Kip1) and control of cyclin D1 expression.
    Cappellini A; Tabellini G; Zweyer M; Bortul R; Tazzari PL; Billi AM; Falà F; Cocco L; Martelli AM
    Leukemia; 2003 Nov; 17(11):2157-67. PubMed ID: 12931221
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytokine-induced phosphoinositide 3-kinase activity promotes Cdk2 activation in factor-dependent hematopoietic cells.
    Henry MK; Nimbalkar D; Hohl RJ; Quelle FW
    Exp Cell Res; 2004 Sep; 299(1):257-66. PubMed ID: 15302592
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Somatostatin interferes with thyrotropin-induced G1-S transition mediated by cAMP-dependent protein kinase and phosphatidylinositol 3-kinase. Involvement of RhoA and cyclin E x cyclin-dependent kinase 2 complexes.
    Medina DL; Toro MJ; Santisteban P
    J Biol Chem; 2000 May; 275(20):15549-56. PubMed ID: 10809788
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cyclic AMP-dependent phosphorylation of cyclin D3-bound CDK4 determines the passage through the cell cycle restriction point in thyroid epithelial cells.
    Paternot S; Coulonval K; Dumont JE; Roger PP
    J Biol Chem; 2003 Jul; 278(29):26533-40. PubMed ID: 12730225
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.