BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

427 related articles for article (PubMed ID: 12941762)

  • 21. Insulin signaling in insulin receptor substrate (IRS)-1-deficient brown adipocytes: requirement of IRS-1 for lipid synthesis.
    Valverde AM; Kahn CR; Benito M
    Diabetes; 1999 Nov; 48(11):2122-31. PubMed ID: 10535444
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling.
    Schattenberg JM; Wang Y; Singh R; Rigoli RM; Czaja MJ
    J Biol Chem; 2005 Mar; 280(11):9887-94. PubMed ID: 15632182
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Glucosamine infusion in rats rapidly impairs insulin stimulation of phosphoinositide 3-kinase but does not alter activation of Akt/protein kinase B in skeletal muscle.
    Kim YB; Zhu JS; Zierath JR; Shen HQ; Baron AD; Kahn BB
    Diabetes; 1999 Feb; 48(2):310-20. PubMed ID: 10334307
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Acute selective glycogen synthase kinase-3 inhibition enhances insulin signaling in prediabetic insulin-resistant rat skeletal muscle.
    Dokken BB; Sloniger JA; Henriksen EJ
    Am J Physiol Endocrinol Metab; 2005 Jun; 288(6):E1188-94. PubMed ID: 15671078
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Prolonged treatment of primary hepatocytes with oleate induces insulin resistance through p38 mitogen-activated protein kinase.
    Liu HY; Collins QF; Xiong Y; Moukdar F; Lupo EG; Liu Z; Cao W
    J Biol Chem; 2007 May; 282(19):14205-12. PubMed ID: 17384440
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Insulin down-regulates insulin receptor substrate-2 expression through the phosphatidylinositol 3-kinase/Akt pathway.
    Hirashima Y; Tsuruzoe K; Kodama S; Igata M; Toyonaga T; Ueki K; Kahn CR; Araki E
    J Endocrinol; 2003 Nov; 179(2):253-66. PubMed ID: 14596677
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Inhibition of PTP1B restores IRS1-mediated hepatic insulin signaling in IRS2-deficient mice.
    González-Rodríguez A; Mas Gutierrez JA; Sanz-González S; Ros M; Burks DJ; Valverde AM
    Diabetes; 2010 Mar; 59(3):588-99. PubMed ID: 20028942
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Muscle fiber type-specific defects in insulin signal transduction to glucose transport in diabetic GK rats.
    Song XM; Kawano Y; Krook A; Ryder JW; Efendic S; Roth RA; Wallberg-Henriksson H; Zierath JR
    Diabetes; 1999 Mar; 48(3):664-70. PubMed ID: 10078575
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
    Ozes ON; Akca H; Mayo LD; Gustin JA; Maehama T; Dixon JE; Donner DB
    Proc Natl Acad Sci U S A; 2001 Apr; 98(8):4640-5. PubMed ID: 11287630
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Insulin-induced cell cycle progression is impaired in chinese hamster ovary cells overexpressing insulin receptor substrate-3.
    Kaburagi Y; Yamashita R; Ito Y; Okochi H; Yamamoto-Honda R; Yasuda K; Sekihara H; Sasazuki T; Kadowaki T; Yazaki Y
    Endocrinology; 2004 Dec; 145(12):5862-74. PubMed ID: 15331570
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Interferon-dependent activation of the serine kinase PI 3'-kinase requires engagement of the IRS pathway but not the Stat pathway.
    Uddin S; Majchrzak B; Wang PC; Modi S; Khan MK; Fish EN; Platanias LC
    Biochem Biophys Res Commun; 2000 Apr; 270(1):158-62. PubMed ID: 10733921
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.
    Lingohr MK; Dickson LM; McCuaig JF; Hugl SR; Twardzik DR; Rhodes CJ
    Diabetes; 2002 Apr; 51(4):966-76. PubMed ID: 11916914
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/protein kinase B and atypical protein kinase C (zeta/lambda) activities.
    Tremblay F; Lavigne C; Jacques H; Marette A
    Diabetes; 2001 Aug; 50(8):1901-10. PubMed ID: 11473054
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: amelioration by rosiglitazone and exercise.
    Beeson M; Sajan MP; Dizon M; Grebenev D; Gomez-Daspet J; Miura A; Kanoh Y; Powe J; Bandyopadhyay G; Standaert ML; Farese RV
    Diabetes; 2003 Aug; 52(8):1926-34. PubMed ID: 12882907
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice.
    Gum RJ; Gaede LL; Koterski SL; Heindel M; Clampit JE; Zinker BA; Trevillyan JM; Ulrich RG; Jirousek MR; Rondinone CM
    Diabetes; 2003 Jan; 52(1):21-8. PubMed ID: 12502489
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Insulin receptor substrate 3 (IRS-3) and IRS-4 impair IRS-1- and IRS-2-mediated signaling.
    Tsuruzoe K; Emkey R; Kriauciunas KM; Ueki K; Kahn CR
    Mol Cell Biol; 2001 Jan; 21(1):26-38. PubMed ID: 11113178
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Bile acids enhance the activity of the insulin receptor and glycogen synthase in primary rodent hepatocytes.
    Han SI; Studer E; Gupta S; Fang Y; Qiao L; Li W; Grant S; Hylemon PB; Dent P
    Hepatology; 2004 Feb; 39(2):456-63. PubMed ID: 14767998
    [TBL] [Abstract][Full Text] [Related]  

  • 38. GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.
    Annerén C; Welsh M
    Mol Med; 2002 Nov; 8(11):705-13. PubMed ID: 12520087
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Endurance exercise training increases APPL1 expression and improves insulin signaling in the hepatic tissue of diet-induced obese mice, independently of weight loss.
    Marinho R; Ropelle ER; Cintra DE; De Souza CT; Da Silva AS; Bertoli FC; Colantonio E; D'Almeida V; Pauli JR
    J Cell Physiol; 2012 Jul; 227(7):2917-26. PubMed ID: 21938726
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Serine 332 phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 attenuates insulin signaling.
    Liberman Z; Eldar-Finkelman H
    J Biol Chem; 2005 Feb; 280(6):4422-8. PubMed ID: 15574412
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 22.