BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 12943231)

  • 1. Inactivation of Ret/Ptc1 oncoprotein and inhibition of papillary thyroid carcinoma cell proliferation by indolinone RPI-1.
    Lanzi C; Cassinelli G; Cuccuru G; Zaffaroni N; Supino R; Vignati S; Zanchi C; Yamamoto M; Zunino F
    Cell Mol Life Sci; 2003 Jul; 60(7):1449-59. PubMed ID: 12943231
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cellular effects and antitumor activity of RET inhibitor RPI-1 on MEN2A-associated medullary thyroid carcinoma.
    Cuccuru G; Lanzi C; Cassinelli G; Pratesi G; Tortoreto M; Petrangolini G; Seregni E; Martinetti A; Laccabue D; Zanchi C; Zunino F
    J Natl Cancer Inst; 2004 Jul; 96(13):1006-14. PubMed ID: 15240784
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RET/PTC oncoproteins: molecular targets of new drugs.
    Lanzi C; Cassinelli G; Cuccuru G; Zanchi C; Laccabue D; Zunino F
    Tumori; 2003; 89(5):520-2. PubMed ID: 14870776
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein Rho.
    Barone MV; Sepe L; Melillo RM; Mineo A; Santelli G; Monaco C; Castellone MD; Tramontano D; Fusco A; Santoro M
    Oncogene; 2001 Oct; 20(48):6973-82. PubMed ID: 11704822
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Assessment of RET/PTC oncogene activation and clonality in thyroid nodules with incomplete morphological evidence of papillary carcinoma: a search for the early precursors of papillary cancer.
    Fusco A; Chiappetta G; Hui P; Garcia-Rostan G; Golden L; Kinder BK; Dillon DA; Giuliano A; Cirafici AM; Santoro M; Rosai J; Tallini G
    Am J Pathol; 2002 Jun; 160(6):2157-67. PubMed ID: 12057919
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of transforming activity of the ret/ptc1 oncoprotein by a 2-indolinone derivative.
    Lanzi C; Cassinelli G; Pensa T; Cassinis M; Gambetta RA; Borrello MG; Menta E; Pierotti MA; Zunino F
    Int J Cancer; 2000 Feb; 85(3):384-90. PubMed ID: 10652431
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Low prevalence of RET rearrangements (RET/PTC1, RET/PTC2, RET/PTC3, and ELKS-RET) in sporadic papillary thyroid carcinomas in Taiwan Chinese.
    Liu RT; Chou FF; Wang CH; Lin CL; Chao FP; Chung JC; Huang CC; Wang PW; Cheng JT
    Thyroid; 2005 Apr; 15(4):326-35. PubMed ID: 15876154
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Real-time quantitative RT-PCR identifies distinct c-RET, RET/PTC1 and RET/PTC3 expression patterns in papillary thyroid carcinoma.
    Rhoden KJ; Johnson C; Brandao G; Howe JG; Smith BR; Tallini G
    Lab Invest; 2004 Dec; 84(12):1557-70. PubMed ID: 15502856
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prevalence and distribution of ret/ptc 1, 2, and 3 in papillary thyroid carcinoma in New Caledonia and Australia.
    Chua EL; Wu WM; Tran KT; McCarthy SW; Lauer CS; Dubourdieu D; Packham N; O'Brien CJ; Turtle JR; Dong Q
    J Clin Endocrinol Metab; 2000 Aug; 85(8):2733-9. PubMed ID: 10946873
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of MEN2A-derived RET in maintenance and proliferation of medullary thyroid carcinoma.
    Drosten M; Hilken G; Böckmann M; Rödicker F; Mise N; Cranston AN; Dahmen U; Ponder BA; Pützer BM
    J Natl Cancer Inst; 2004 Aug; 96(16):1231-9. PubMed ID: 15316058
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2).
    Carlomagno F; Vitagliano D; Guida T; Basolo F; Castellone MD; Melillo RM; Fusco A; Santoro M
    J Clin Endocrinol Metab; 2003 Apr; 88(4):1897-902. PubMed ID: 12679489
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Apoptotic cell death induction and angiogenesis inhibition in large established medullary thyroid carcinoma xenografts by Ret inhibitor RPI-1.
    Petrangolini G; Cuccuru G; Lanzi C; Tortoreto M; Belluco S; Pratesi G; Cassinelli G; Zunino F
    Biochem Pharmacol; 2006 Aug; 72(4):405-14. PubMed ID: 16756963
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dasatinib reduces FAK phosphorylation increasing the effects of RPI-1 inhibition in a RET/PTC1-expressing cell line.
    Caccia D; Miccichè F; Cassinelli G; Mondellini P; Casalini P; Bongarzone I
    Mol Cancer; 2010 Oct; 9():278. PubMed ID: 20955590
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The roles of phosphotyrosines-294, -404, and -451 in RET/PTC1-induced thyroid tumor formation.
    Buckwalter TL; Venkateswaran A; Lavender M; La Perle KM; Cho JY; Robinson ML; Jhiang SM
    Oncogene; 2002 Nov; 21(53):8166-72. PubMed ID: 12444552
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RET/PTC activation in hyalinizing trabecular tumors of the thyroid.
    Papotti M; Volante M; Giuliano A; Fassina A; Fusco A; Bussolati G; Santoro M; Chiappetta G
    Am J Surg Pathol; 2000 Dec; 24(12):1615-21. PubMed ID: 11117781
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of signal transducer and activator of transcription 1 (STAT1) and STAT1-dependent genes by RET/PTC (rearranged in transformation/papillary thyroid carcinoma) oncogenic tyrosine kinases.
    Hwang ES; Kim DW; Hwang JH; Jung HS; Suh JM; Park YJ; Chung HK; Song JH; Park KC; Park SH; Yun HJ; Kim JM; Shong M
    Mol Endocrinol; 2004 Nov; 18(11):2672-84. PubMed ID: 15297606
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thyroid carcinomas in RET/PTC transgenic mice.
    Jhiang SM; Cho JY; Furminger TL; Sagartz JE; Tong Q; Capen CC; Mazzaferri EL
    Recent Results Cancer Res; 1998; 154():265-70. PubMed ID: 10027006
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of silencing RET/PTC1 junction oncogene in human papillary thyroid carcinoma cells.
    Gilbert-Sirieix M; Ripoche H; Malvy C; Massaad-Massade L
    Thyroid; 2010 Oct; 20(10):1053-65. PubMed ID: 20615140
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Creation and characterization of a doxycycline-inducible mouse model of thyroid-targeted RET/PTC1 oncogene and luciferase reporter gene coexpression.
    Knostman KA; Venkateswaran A; Zimmerman B; Capen CC; Jhiang SM
    Thyroid; 2007 Dec; 17(12):1181-8. PubMed ID: 18004977
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Concurrent overexpression of RET/PTC1 and TTF1 confers tumorigenicity to thyrocytes.
    Endo T; Kobayashi T
    Endocr Relat Cancer; 2013 Dec; 20(6):767-76. PubMed ID: 24014739
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.