BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 12943706)

  • 1. Functional properties of the N-terminal region of progesterone receptors and their mechanistic relationship to structure.
    Takimoto GS; Tung L; Abdel-Hafiz H; Abel MG; Sartorius CA; Richer JK; Jacobsen BM; Bain DL; Horwitz KB
    J Steroid Biochem Mol Biol; 2003 Jun; 85(2-5):209-19. PubMed ID: 12943706
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform.
    Sartorius CA; Melville MY; Hovland AR; Tung L; Takimoto GS; Horwitz KB
    Mol Endocrinol; 1994 Oct; 8(10):1347-60. PubMed ID: 7854352
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mapping the unique activation function 3 in the progesterone B-receptor upstream segment. Two LXXLL motifs and a tryptophan residue are required for activity.
    Tung L; Shen T; Abel MG; Powell RL; Takimoto GS; Sartorius CA; Horwitz KB
    J Biol Chem; 2001 Oct; 276(43):39843-51. PubMed ID: 11546784
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Progesterone receptors (PR)-B and -A regulate transcription by different mechanisms: AF-3 exerts regulatory control over coactivator binding to PR-B.
    Tung L; Abdel-Hafiz H; Shen T; Harvell DM; Nitao LK; Richer JK; Sartorius CA; Takimoto GS; Horwitz KB
    Mol Endocrinol; 2006 Nov; 20(11):2656-70. PubMed ID: 16762974
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An N-terminal inhibitory function, IF, suppresses transcription by the A-isoform but not the B-isoform of human progesterone receptors.
    Hovland AR; Powell RL; Takimoto GS; Tung L; Horwitz KB
    J Biol Chem; 1998 Mar; 273(10):5455-60. PubMed ID: 9488667
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of phosphorylation on DNA binding and transcriptional functions of human progesterone receptors.
    Takimoto GS; Hovland AR; Tasset DM; Melville MY; Tung L; Horwitz KB
    J Biol Chem; 1996 Jun; 271(23):13308-16. PubMed ID: 8662865
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Progesterone receptor interacting coregulatory proteins and cross talk with cell signaling pathways.
    Edwards DP; Wardell SE; Boonyaratanakornkit V
    J Steroid Biochem Mol Biol; 2002 Dec; 83(1-5):173-86. PubMed ID: 12650714
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The inhibitory function in human progesterone receptor N termini binds SUMO-1 protein to regulate autoinhibition and transrepression.
    Abdel-Hafiz H; Takimoto GS; Tung L; Horwitz KB
    J Biol Chem; 2002 Sep; 277(37):33950-6. PubMed ID: 12114521
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Delineation of critical amino acids in activation function 1 of progesterone receptor for recruitment of transcription coregulators.
    Woo ARE; Sze SK; Chung HH; Lin VC
    Biochim Biophys Acta Gene Regul Mech; 2019 Apr; 1862(4):522-533. PubMed ID: 30716532
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hinge and amino-terminal sequences contribute to solution dimerization of human progesterone receptor.
    Tetel MJ; Jung S; Carbajo P; Ladtkow T; Skafar DF; Edwards DP
    Mol Endocrinol; 1997 Jul; 11(8):1114-28. PubMed ID: 9212059
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hormone-dependent interaction between the amino- and carboxyl-terminal domains of progesterone receptor in vitro and in vivo.
    Tetel MJ; Giangrande PH; Leonhardt SA; McDonnell DP; Edwards DP
    Mol Endocrinol; 1999 Jun; 13(6):910-24. PubMed ID: 10379890
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA bending is induced by binding of the glucocorticoid receptor DNA binding domain and progesterone receptors to their response element.
    Petz LN; Nardulli AM; Kim J; Horwitz KB; Freedman LP; Shapiro DJ
    J Steroid Biochem Mol Biol; 1997 Jan; 60(1-2):31-41. PubMed ID: 9182856
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intramolecular interactions between the AF3 domain and the C-terminus of the human progesterone receptor are mediated through two LXXLL motifs.
    Dong X; Challis JR; Lye SJ
    J Mol Endocrinol; 2004 Jun; 32(3):843-57. PubMed ID: 15171716
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor.
    Vegeto E; Allan GF; Schrader WT; Tsai MJ; McDonnell DP; O'Malley BW
    Cell; 1992 May; 69(4):703-13. PubMed ID: 1586949
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of the amino-terminal transcription activation domain of progesterone receptor by a cofactor-induced protein folding mechanism.
    Wardell SE; Kwok SC; Sherman L; Hodges RS; Edwards DP
    Mol Cell Biol; 2005 Oct; 25(20):8792-808. PubMed ID: 16199860
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Canid progesterone receptors lack activation function 3 domain-dependent activity.
    Gracanin A; van Wolferen ME; Sartorius CA; Brenkman AB; Schoonen WG; Mol JA
    Endocrinology; 2012 Dec; 153(12):6104-13. PubMed ID: 23041671
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mapping and characterization of the functional domains responsible for the differential activity of the A and B isoforms of the human progesterone receptor.
    Giangrande PH; Pollio G; McDonnell DP
    J Biol Chem; 1997 Dec; 272(52):32889-900. PubMed ID: 9407067
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Agonist and antagonists induce homodimerization and mixed ligand heterodimerization of human progesterone receptors in vivo by a mammalian two-hybrid assay.
    Leonhardt SA; Altmann M; Edwards DP
    Mol Endocrinol; 1998 Dec; 12(12):1914-30. PubMed ID: 9849965
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Self-association energetics of an intact, full-length nuclear receptor: the B-isoform of human progesterone receptor dimerizes in the micromolar range.
    Heneghan AF; Berton N; Miura MT; Bain DL
    Biochemistry; 2005 Jul; 44(27):9528-37. PubMed ID: 15996107
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ALU repeats in promoters are position-dependent co-response elements (coRE) that enhance or repress transcription by dimeric and monomeric progesterone receptors.
    Jacobsen BM; Jambal P; Schittone SA; Horwitz KB
    Mol Endocrinol; 2009 Jul; 23(7):989-1000. PubMed ID: 19372234
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.