BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 12948013)

  • 1. Quantitative evaluation of the function of small intestinal P-glycoprotein: comparative studies between in situ and in vitro.
    Adachi Y; Suzuki H; Sugiyama Y
    Pharm Res; 2003 Aug; 20(8):1163-9. PubMed ID: 12948013
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge.
    Yu XY; Lin SG; Zhou ZW; Chen X; Liang J; Liu PQ; Duan W; Chowbay B; Wen JY; Li CG; Zhou SF
    Curr Drug Metab; 2007 May; 8(4):325-40. PubMed ID: 17504222
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium.
    Troutman MD; Thakker DR
    Pharm Res; 2003 Aug; 20(8):1210-24. PubMed ID: 12948019
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein.
    Adachi Y; Suzuki H; Sugiyama Y
    Pharm Res; 2001 Dec; 18(12):1660-8. PubMed ID: 11785684
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Blood-brain barrier (BBB) pharmacoproteomics: reconstruction of in vivo brain distribution of 11 P-glycoprotein substrates based on the BBB transporter protein concentration, in vitro intrinsic transport activity, and unbound fraction in plasma and brain in mice.
    Uchida Y; Ohtsuki S; Kamiie J; Terasaki T
    J Pharmacol Exp Ther; 2011 Nov; 339(2):579-88. PubMed ID: 21828264
    [TBL] [Abstract][Full Text] [Related]  

  • 6. P-gp is involved in the intestinal absorption and biliary excretion of afatinib in vitro and in rats.
    Zhang Y; Wang C; Liu Z; Meng Q; Huo X; Liu Q; Sun P; Yang X; Sun H; Ma X; Liu K
    Pharmacol Rep; 2018 Apr; 70(2):243-250. PubMed ID: 29475007
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparative effects on intestinal absorption in situ by P-glycoprotein-modifying HIV protease inhibitors.
    Richter M; Gyémánt N; Molnár J; Hilgeroth A
    Pharm Res; 2004 Oct; 21(10):1862-6. PubMed ID: 15553233
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modulation of expression/function of intestinal P-glycoprotein under disease states.
    Murakami T; Bodor E; Bodor N
    Expert Opin Drug Metab Toxicol; 2020 Jan; 16(1):59-78. PubMed ID: 31821048
    [No Abstract]   [Full Text] [Related]  

  • 9. Efflux ratio cannot assess P-glycoprotein-mediated attenuation of absorptive transport: asymmetric effect of P-glycoprotein on absorptive and secretory transport across Caco-2 cell monolayers.
    Troutman MD; Thakker DR
    Pharm Res; 2003 Aug; 20(8):1200-9. PubMed ID: 12948018
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of P-Glycoprotein Humanized Mice Generated by Chromosome Engineering Technology: Its Utility for Prediction of Drug Distribution to the Brain in Humans.
    Yamasaki Y; Kobayashi K; Okuya F; Kajitani N; Kazuki K; Abe S; Takehara S; Ito S; Ogata S; Uemura T; Ohtsuki S; Minegishi G; Akita H; Chiba K; Oshimura M; Kazuki Y
    Drug Metab Dispos; 2018 Nov; 46(11):1756-1766. PubMed ID: 29777024
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regional difference in P-glycoprotein function in rat intestine.
    Iida A; Tomita M; Hayashi M
    Drug Metab Pharmacokinet; 2005 Apr; 20(2):100-6. PubMed ID: 15855720
    [TBL] [Abstract][Full Text] [Related]  

  • 12. What kinds of substrates show P-glycoprotein-dependent intestinal absorption? Comparison of verapamil with vinblastine.
    Ogihara T; Kamiya M; Ozawa M; Fujita T; Yamamoto A; Yamashita S; Ohnishi S; Isomura Y
    Drug Metab Pharmacokinet; 2006 Jun; 21(3):238-44. PubMed ID: 16858128
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Commonly used surfactant, Tween 80, improves absorption of P-glycoprotein substrate, digoxin, in rats.
    Zhang H; Yao M; Morrison RA; Chong S
    Arch Pharm Res; 2003 Sep; 26(9):768-72. PubMed ID: 14560928
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of P-glycoprotein-mediated secretion in absorptive drug permeability: An approach using passive membrane permeability and affinity to P-glycoprotein.
    Döppenschmitt S; Spahn-Langguth H; Regårdh CG; Langguth P
    J Pharm Sci; 1999 Oct; 88(10):1067-72. PubMed ID: 10514357
    [TBL] [Abstract][Full Text] [Related]  

  • 15. pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs: kinetic analysis of quinidine efflux in situ.
    Varma MV; Panchagnula R
    J Pharm Sci; 2005 Dec; 94(12):2632-43. PubMed ID: 16258992
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanistic analysis for drug permeation through intestinal membrane.
    Hayashi M; Tomita M
    Drug Metab Pharmacokinet; 2007 Apr; 22(2):67-77. PubMed ID: 17495413
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In situ transport of vinblastine and selected P-glycoprotein substrates: implications for drug-drug interactions at the mouse blood-brain barrier.
    Cisternino S; Rousselle C; Debray M; Scherrmann JM
    Pharm Res; 2004 Aug; 21(8):1382-9. PubMed ID: 15359572
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Segmental dependent transport of low permeability compounds along the small intestine due to P-glycoprotein: the role of efflux transport in the oral absorption of BCS class III drugs.
    Dahan A; Amidon GL
    Mol Pharm; 2009; 6(1):19-28. PubMed ID: 19248230
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Limited role of P-glycoprotein in the intestinal absorption of cyclosporin A.
    Lee YJ; Chung SJ; Shim CK
    Biol Pharm Bull; 2005 Apr; 28(4):760-3. PubMed ID: 15802827
    [TBL] [Abstract][Full Text] [Related]  

  • 20. (R)- and (S)-[11C]verapamil as PET-tracers for measuring P-glycoprotein function: in vitro and in vivo evaluation.
    Luurtsema G; Molthoff CF; Windhorst AD; Smit JW; Keizer H; Boellaard R; Lammertsma AA; Franssen EJ
    Nucl Med Biol; 2003 Oct; 30(7):747-51. PubMed ID: 14499333
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.