These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 12952479)

  • 41. An additional spirocyclization for duocarmycin SA.
    MacMillan KS; Boger DL
    J Am Chem Soc; 2008 Dec; 130(49):16521-3. PubMed ID: 19554689
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole conjugates with remarkable DNA-binding affinity.
    Kamal A; Ramulu P; Srinivas O; Ramesh G; Kumar PP
    Bioorg Med Chem Lett; 2004 Sep; 14(18):4791-4. PubMed ID: 15324909
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Total synthesis of (+)-yatakemycin.
    Okano K; Tokuyama H; Fukuyama T
    Chem Asian J; 2008 Feb; 3(2):296-309. PubMed ID: 18000998
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Substituent effects within the DNA binding subunit of CBI analogues of the duocarmycins and CC-1065.
    Boger DL; Stauffer F; Hedrick MP
    Bioorg Med Chem Lett; 2001 Aug; 11(15):2021-4. PubMed ID: 11454471
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Demonstration by real-time polymerase chain reaction that cellular DNA alkylation by novel aminoindoline compounds affects expression of the protooncogene c-myc.
    Nelson SM; Ferguson LR; Denny WA
    Chem Res Toxicol; 2005 Feb; 18(2):239-48. PubMed ID: 15720128
    [TBL] [Abstract][Full Text] [Related]  

  • 46. A novel class of in vivo active anticancer agents: achiral seco-amino- and seco-hydroxycyclopropylbenz[e]indolone (seco-CBI) analogues of the duocarmycins and CC-1065.
    Sato A; McNulty L; Cox K; Kim S; Scott A; Daniell K; Summerville K; Price C; Hudson S; Kiakos K; Hartley JA; Asao T; Lee M
    J Med Chem; 2005 Jun; 48(11):3903-18. PubMed ID: 15916443
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Synthesis and antiproliferative activity of some new DNA-targeted alkylating pyrroloquinolines.
    Ferlin MG; Dalla Via L; Gia OM
    Bioorg Med Chem; 2004 Feb; 12(4):771-7. PubMed ID: 14759737
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Design, synthesis, and biophysical and biological evaluation of a series of pyrrolobenzodiazepine-poly(N-methylpyrrole) conjugates.
    Wells G; Martin CR; Howard PW; Sands ZA; Laughton CA; Tiberghien A; Woo CK; Masterson LA; Stephenson MJ; Hartley JA; Jenkins TC; Shnyder SD; Loadman PM; Waring MJ; Thurston DE
    J Med Chem; 2006 Sep; 49(18):5442-61. PubMed ID: 16942018
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Synthesis and evaluation of sequence-specific DNA alkylating agents: effect of alkylation subunits.
    Shimizu T; Sasaki S; Minoshima M; Shinohara K; Bando T; Sugiyama H
    Nucleic Acids Symp Ser (Oxf); 2006; (50):155-6. PubMed ID: 17150864
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Synthesis and evaluation of duocarmycin SA analogs incorporating the methyl 1,2,8,8a-tetrahydrocyclopropa[c]oxazolo[2,3-e]indol-4-one-6-carboxylate (COI) alkylation subunit.
    Boyle KE; MacMillan KS; Ellis DA; Lajiness JP; Robertson WM; Boger DL
    Bioorg Med Chem Lett; 2010 Mar; 20(6):1854-7. PubMed ID: 20171886
    [TBL] [Abstract][Full Text] [Related]  

  • 51. DNA Interstrand Crosslinks by H-pin Polyamide (S)-seco-CBI Conjugates.
    Guo C; Asamitsu S; Kashiwazaki G; Sato S; Bando T; Sugiyama H
    Chembiochem; 2017 Jan; 18(2):166-170. PubMed ID: 27862755
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Synthesis and biological evaluation of novel pyrrolopyrrolizinones as anticancer agents.
    Rochais C; Lisowski V; Dallemagne P; Rault S
    Bioorg Med Chem; 2006 Dec; 14(24):8162-75. PubMed ID: 17011196
    [TBL] [Abstract][Full Text] [Related]  

  • 53. DNA adducts of N-nitrosoureas.
    Eisenbrand G; Pfeiffer C; Tang W
    IARC Sci Publ; 1994; (125):277-93. PubMed ID: 7806318
    [No Abstract]   [Full Text] [Related]  

  • 54. Acenaphtho[1,2-b]pyrrole derivatives as new family of intercalators: various DNA binding geometry and interesting antitumor capacity.
    Zhang Z; Yang Y; Zhang D; Wang Y; Qian X; Liu F
    Bioorg Med Chem; 2006 Oct; 14(20):6962-70. PubMed ID: 16828559
    [TBL] [Abstract][Full Text] [Related]  

  • 55. DNA-based electrochemical biosensors for monitoring of bis-indoles as potential antitumoral agents, chemistry, X-ray crystallography.
    Maciejewska D; Szpakowska I; Wolska I; Niemyjska M; Mascini M; Maj-Zurawska M
    Bioelectrochemistry; 2006 Sep; 69(1):1-9. PubMed ID: 16307909
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Fundamental relationships between structure, reactivity, and biological activity for the duocarmycins and CC-1065.
    MacMillan KS; Boger DL
    J Med Chem; 2009 Oct; 52(19):5771-80. PubMed ID: 19639994
    [No Abstract]   [Full Text] [Related]  

  • 57. Total synthesis and biological properties of novel antineoplastic (chloromethyl)furanoindolines: an asymmetric hydroboration mediated synthesis of the alkylation subunits.
    Mohamadi F; Spees MM; Staten GS; Marder P; Kipka JK; Johnson DA; Boger DL; Zarrinmayeh H
    J Med Chem; 1994 Jan; 37(2):232-9. PubMed ID: 8295210
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Conformationally restricted analogs of Combretastatin A-4 derived from SU5416.
    Li PK; Xiao Z; Hu Z; Pandit B; Sun Y; Sackett DL; Werbovetz K; Lewis A; Johnsamuel J
    Bioorg Med Chem Lett; 2005 Dec; 15(24):5382-5. PubMed ID: 16213720
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Cytotoxic alpha-halogenoacrylic derivatives of distamycin A and congeners.
    Beria I; Baraldi PG; Cozzi P; Caldarelli M; Geroni C; Marchini S; Mongelli N; Romagnoli R
    J Med Chem; 2004 May; 47(10):2611-23. PubMed ID: 15115402
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Asymmetric synthesis and biological evaluation of glycosidic prodrugs for a selective cancer therapy.
    Tietze LF; von Hof JM; Krewer B; Müller M; Major F; Schuster HJ; Schuberth I; Alves F
    ChemMedChem; 2008 Dec; 3(12):1946-55. PubMed ID: 19021160
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.