BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 12952864)

  • 1. Regional differences of somatic CAG repeat instability do not account for selective neuronal vulnerability in a knock-in mouse model of SCA1.
    Watase K; Venken KJ; Sun Y; Orr HT; Zoghbi HY
    Hum Mol Genet; 2003 Nov; 12(21):2789-95. PubMed ID: 12952864
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Somatic mosaicism of the CAG repeat expansion in spinocerebellar ataxia type 3/Machado-Joseph disease.
    Cancel G; Gourfinkel-An I; Stevanin G; Didierjean O; Abbas N; Hirsch E; Agid Y; Brice A
    Hum Mutat; 1998; 11(1):23-7. PubMed ID: 9450899
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Somatic mosaicism in the central nervous system in spinocerebellar ataxia type 1 and Machado-Joseph disease.
    Lopes-Cendes I; Maciel P; Kish S; Gaspar C; Robitaille Y; Clark HB; Koeppen AH; Nance M; Schut L; Silveira I; Coutinho P; Sequeiros J; Rouleau GA
    Ann Neurol; 1996 Aug; 40(2):199-206. PubMed ID: 8773601
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A SCA7 CAG/CTG repeat expansion is stable in Drosophila melanogaster despite modulation of genomic context and gene dosage.
    Jackson SM; Whitworth AJ; Greene JC; Libby RT; Baccam SL; Pallanck LJ; La Spada AR
    Gene; 2005 Feb; 347(1):35-41. PubMed ID: 15715978
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transgenic mouse models of neurodegenerative disease caused by CAG/polyglutamine expansions.
    Bates GP; Davies SW
    Mol Med Today; 1997 Nov; 3(11):508-15. PubMed ID: 9430787
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice.
    Manley K; Shirley TL; Flaherty L; Messer A
    Nat Genet; 1999 Dec; 23(4):471-3. PubMed ID: 10581038
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CAG repeat disorder models and human neuropathology: similarities and differences.
    Yamada M; Sato T; Tsuji S; Takahashi H
    Acta Neuropathol; 2008 Jan; 115(1):71-86. PubMed ID: 17786457
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quantification of age-dependent somatic CAG repeat instability in Hdh CAG knock-in mice reveals different expansion dynamics in striatum and liver.
    Lee JM; Pinto RM; Gillis T; St Claire JC; Wheeler VC
    PLoS One; 2011; 6(8):e23647. PubMed ID: 21897851
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Somatic CTG*CAG repeat instability in a mouse model for myotonic dystrophy type 1 is associated with changes in cell nuclearity and DNA ploidy.
    van den Broek WJ; Wansink DG; Wieringa B
    BMC Mol Biol; 2007 Jul; 8():61. PubMed ID: 17645799
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gametic and somatic tissue-specific heterogeneity of the expanded SCA1 CAG repeat in spinocerebellar ataxia type 1.
    Chong SS; McCall AE; Cota J; Subramony SH; Orr HT; Hughes MR; Zoghbi HY
    Nat Genet; 1995 Jul; 10(3):344-50. PubMed ID: 7670474
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Unstable expansion of CAG repeat and molecular mechanism of neurodegeneration in SCA1].
    Sasaki H
    Nihon Rinsho; 1999 Apr; 57(4):801-4. PubMed ID: 10222769
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Xpa deficiency reduces CAG trinucleotide repeat instability in neuronal tissues in a mouse model of SCA1.
    Hubert L; Lin Y; Dion V; Wilson JH
    Hum Mol Genet; 2011 Dec; 20(24):4822-30. PubMed ID: 21926083
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Somatic mosaicism of expanded CAG trinucleotide repeat in the neural and nonneural tissues of Machado-Joseph disease (MJD)].
    Tanaka F; Ito Y; Sobue G
    Nihon Rinsho; 1999 Apr; 57(4):838-42. PubMed ID: 10222776
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Possible reduced penetrance of expansion of 44 to 47 CAG/CAA repeats in the TATA-binding protein gene in spinocerebellar ataxia type 17.
    Oda M; Maruyama H; Komure O; Morino H; Terasawa H; Izumi Y; Imamura T; Yasuda M; Ichikawa K; Ogawa M; Matsumoto M; Kawakami H
    Arch Neurol; 2004 Feb; 61(2):209-12. PubMed ID: 14967767
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation.
    Mangiarini L; Sathasivam K; Mahal A; Mott R; Seller M; Bates GP
    Nat Genet; 1997 Feb; 15(2):197-200. PubMed ID: 9020849
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Somatic mosaicism of CAG repeats size in the nervous system of dentatorubral-pallidoluysian atrophy (DRPLA)].
    Ito Y; Tanaka F; Sobue G
    Nihon Rinsho; 1999 Apr; 57(4):850-5. PubMed ID: 10222778
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Age-dependent and tissue-specific CAG repeat instability occurs in mouse knock-in for a mutant Huntington's disease gene.
    Ishiguro H; Yamada K; Sawada H; Nishii K; Ichino N; Sawada M; Kurosawa Y; Matsushita N; Kobayashi K; Goto J; Hashida H; Masuda N; Kanazawa I; Nagatsu T
    J Neurosci Res; 2001 Aug; 65(4):289-97. PubMed ID: 11494364
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neuronal dysfunction in a polyglutamine disease model occurs in the absence of ubiquitin-proteasome system impairment and inversely correlates with the degree of nuclear inclusion formation.
    Bowman AB; Yoo SY; Dantuma NP; Zoghbi HY
    Hum Mol Genet; 2005 Mar; 14(5):679-91. PubMed ID: 15661755
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Age-, tissue- and length-dependent bidirectional somatic CAG•CTG repeat instability in an allelic series of R6/2 Huntington disease mice.
    Larson E; Fyfe I; Morton AJ; Monckton DG
    Neurobiol Dis; 2015 Apr; 76():98-111. PubMed ID: 25662336
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression levels of DNA replication and repair genes predict regional somatic repeat instability in the brain but are not altered by polyglutamine disease protein expression or age.
    Mason AG; Tomé S; Simard JP; Libby RT; Bammler TK; Beyer RP; Morton AJ; Pearson CE; La Spada AR
    Hum Mol Genet; 2014 Mar; 23(6):1606-18. PubMed ID: 24191263
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.