151 related articles for article (PubMed ID: 12955370)
1. Pregnancy and use of oral contraceptives reduces the biotransformation of proguanil to cycloguanil.
McGready R; Stepniewska K; Seaton E; Cho T; Cho D; Ginsberg A; Edstein MD; Ashley E; Looareesuwan S; White NJ; Nosten F
Eur J Clin Pharmacol; 2003 Oct; 59(7):553-7. PubMed ID: 12955370
[TBL] [Abstract][Full Text] [Related]
2. The pharmacokinetics and pharmacodynamics of atovaquone and proguanil for the treatment of uncomplicated falciparum malaria in third-trimester pregnant women.
Na-Bangchang K; Manyando C; Ruengweerayut R; Kioy D; Mulenga M; Miller GB; Konsil J
Eur J Clin Pharmacol; 2005 Sep; 61(8):573-82. PubMed ID: 16041597
[TBL] [Abstract][Full Text] [Related]
3. Single dose pharmacokinetics of proguanil and its metabolites in pregnancy.
Wangboonskul J; White NJ; Nosten F; ter Kuile F; Moody RR; Taylor RB
Eur J Clin Pharmacol; 1993; 44(3):247-51. PubMed ID: 8491239
[TBL] [Abstract][Full Text] [Related]
4. The pharmacokinetics of atovaquone and proguanil in pregnant women with acute falciparum malaria.
McGready R; Stepniewska K; Edstein MD; Cho T; Gilveray G; Looareesuwan S; White NJ; Nosten F
Eur J Clin Pharmacol; 2003 Oct; 59(7):545-52. PubMed ID: 12955371
[TBL] [Abstract][Full Text] [Related]
5. Metabolic disposition of proguanil in extensive and poor metabolisers of S-mephenytoin 4'-hydroxylation recruited from an Indonesian population.
Setiabudy R; Kusaka M; Chiba K; Darmansjah I; Ishizaki T
Br J Clin Pharmacol; 1995 Mar; 39(3):297-303. PubMed ID: 7619672
[TBL] [Abstract][Full Text] [Related]
6. Variability in the metabolism of proguanil to the active metabolite cycloguanil in healthy Kenyan adults.
Watkins WM; Mberu EK; Nevill CG; Ward SA; Breckenridge AM; Koech DK
Trans R Soc Trop Med Hyg; 1990; 84(4):492-5. PubMed ID: 2091335
[TBL] [Abstract][Full Text] [Related]
7. Concordance between proguanil phenotype and CYP2C19 genotype in Chinese.
Hoskins JM; Shenfield GM; Gross AS
Eur J Clin Pharmacol; 2003 Nov; 59(8-9):611-4. PubMed ID: 13680037
[TBL] [Abstract][Full Text] [Related]
8. The pharmacokinetics and activation of proguanil in man: consequences of variability in drug metabolism.
Helsby NA; Ward SA; Edwards G; Howells RE; Breckenridge AM
Br J Clin Pharmacol; 1990 Oct; 30(4):593-8. PubMed ID: 2291871
[TBL] [Abstract][Full Text] [Related]
9. The multiple dose pharmacokinetics of proguanil.
Helsby NA; Edwards G; Breckenridge AM; Ward SA
Br J Clin Pharmacol; 1993 Jun; 35(6):653-6. PubMed ID: 8329294
[TBL] [Abstract][Full Text] [Related]
10. The activation of the biguanide antimalarial proguanil co-segregates with the mephenytoin oxidation polymorphism--a panel study.
Ward SA; Helsby NA; Skjelbo E; Brøsen K; Gram LF; Breckenridge AM
Br J Clin Pharmacol; 1991 Jun; 31(6):689-92. PubMed ID: 1867963
[TBL] [Abstract][Full Text] [Related]
11. OCT1 Deficiency Affects Hepatocellular Concentrations and Pharmacokinetics of Cycloguanil, the Active Metabolite of the Antimalarial Drug Proguanil.
Matthaei J; Seitz T; Jensen O; Tann A; Prukop T; Tadjerpisheh S; Brockmöller J; Tzvetkov MV
Clin Pharmacol Ther; 2019 Jan; 105(1):190-200. PubMed ID: 29882324
[TBL] [Abstract][Full Text] [Related]
12. A statistical analysis of the antimalarial activity of proguanil and cycloguanil in human volunteers.
Yeo AE; Edstein MD; Shanks GD; Rieckmann KH
Ann Trop Med Parasitol; 1994 Dec; 88(6):587-94. PubMed ID: 7893172
[TBL] [Abstract][Full Text] [Related]
13. Hepatic cytochrome P450 CYP2C activity in psoriasis: studies using proguanil as a probe compound.
Helsby NA; Ward SA; Parslew RA; Friedmann PS; Rhodes LE
Acta Derm Venereol; 1998 Mar; 78(2):81-3. PubMed ID: 9534880
[TBL] [Abstract][Full Text] [Related]
14. Proguanil disposition and toxicity in malaria patients from Vanuatu with high frequencies of CYP2C19 mutations.
Kaneko A; Bergqvist Y; Taleo G; Kobayakawa T; Ishizaki T; Björkman A
Pharmacogenetics; 1999 Jun; 9(3):317-26. PubMed ID: 10471063
[TBL] [Abstract][Full Text] [Related]
15. Intrinsic efficacy of proguanil against falciparum and vivax malaria independent of the metabolite cycloguanil.
Kaneko A; Bergqvist Y; Takechi M; Kalkoa M; Kaneko O; Kobayakawa T; Ishizaki T; Björkman A
J Infect Dis; 1999 Apr; 179(4):974-9. PubMed ID: 10068594
[TBL] [Abstract][Full Text] [Related]
16. Single dose pharmacokinetics of proguanil and its metabolites in healthy subjects.
Wattanagoon Y; Taylor RB; Moody RR; Ochekpe NA; Looareesuwan S; White NJ
Br J Clin Pharmacol; 1987 Dec; 24(6):775-80. PubMed ID: 3440097
[TBL] [Abstract][Full Text] [Related]
17. Effects of omeprazole and cimetidine on the urinary metabolic ratio of proguanil in healthy volunteers.
Somogyi AA; Reinhard HA; Bochner F
Eur J Clin Pharmacol; 1996; 50(5):417-9. PubMed ID: 8839666
[TBL] [Abstract][Full Text] [Related]
18. Improved validated assay for the determination of proguanil and its metabolites in plasma, whole blood, and urine using solid-phase extraction and high-performance liquid chromatography.
Bergqvist Y; Funding L; Krysèn B; Leek T; Yvell K
Ther Drug Monit; 1998 Jun; 20(3):325-30. PubMed ID: 9631931
[TBL] [Abstract][Full Text] [Related]
19. Assessment of CYP2D6 and CYP2C19 activity in vivo in humans: a cocktail study with dextromethorphan and chloroguanide alone and in combination.
Tennezé L; Verstuyft C; Becquemont L; Poirier JM; Wilkinson GR; Funck-Brentano C
Clin Pharmacol Ther; 1999 Dec; 66(6):582-8. PubMed ID: 10613613
[TBL] [Abstract][Full Text] [Related]
20. Multiple-dose pharmacokinetic study of proguanil and cycloguanil following 12-hourly administration of 100 mg proguanil hydrochloride.
Jamaludin A; Mohamad M; Navaratnam V; Yeoh PY; Wernsdorfer WH
Trop Med Parasitol; 1990 Sep; 41(3):268-72. PubMed ID: 2255843
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
