179 related articles for article (PubMed ID: 12956900)
1. AWD 12-281, a highly selective phosphodiesterase 4 inhibitor, is effective in the prevention and treatment of inflammatory reactions in a model of allergic dermatitis.
Bäumer W; Gorr G; Hoppmann J; Ehinger AM; Rundfeldt C; Kietzmann M
J Pharm Pharmacol; 2003 Aug; 55(8):1107-14. PubMed ID: 12956900
[TBL] [Abstract][Full Text] [Related]
2. Effects of the phosphodiesterase 4 inhibitors SB 207499 and AWD 12-281 on the inflammatory reaction in a model of allergic dermatitis.
Bäumer W; Gorr G; Hoppmann J; Ehinger AM; Ehinger B; Kietzmann M
Eur J Pharmacol; 2002 Jun; 446(1-3):195-200. PubMed ID: 12098602
[TBL] [Abstract][Full Text] [Related]
3. The phosphodiesterase 4 inhibitor AWD 12-281 is active in a new guinea-pig model of allergic skin inflammation predictive of human skin penetration and suppresses both Th1 and Th2 cytokines in mice.
Hoppmann J; Bäumer W; Galetzka C; Höfgen N; Kietzmann M; Rundfeldt C
J Pharm Pharmacol; 2005 Dec; 57(12):1609-17. PubMed ID: 16354405
[TBL] [Abstract][Full Text] [Related]
4. In vivo efficacy in airway disease models of N-(3,5-dichloropyrid-4-yl)-[1-(4-fluorobenzyl)-5-hydroxy-indole-3-yl]-glyoxylic acid amide (AWD 12-281), a selective phosphodiesterase 4 inhibitor for inhaled administration.
Kuss H; Hoefgen N; Johanssen S; Kronbach T; Rundfeldt C
J Pharmacol Exp Ther; 2003 Oct; 307(1):373-85. PubMed ID: 12944497
[TBL] [Abstract][Full Text] [Related]
5. TARC and RANTES, but not CTACK, are induced in two models of allergic contact dermatitis. Effects of cilomilast and diflorasone diacetate on T-cell-attracting chemokines.
Bäumer W; Seegers U; Braun M; Tschernig T; Kietzmann M
Br J Dermatol; 2004 Oct; 151(4):823-30. PubMed ID: 15491423
[TBL] [Abstract][Full Text] [Related]
6. Anti-inflammatory potential of the selective phosphodiesterase 4 inhibitor N-(3,5-dichloro-pyrid-4-yl)-[1-(4-fluorobenzyl)-5-hydroxy-indole-3-yl]-glyoxylic acid amide (AWD 12-281), in human cell preparations.
Draheim R; Egerland U; Rundfeldt C
J Pharmacol Exp Ther; 2004 Feb; 308(2):555-63. PubMed ID: 14610230
[TBL] [Abstract][Full Text] [Related]
7. Cilomilast, tacrolimus and rapamycin modulate dendritic cell function in the elicitation phase of allergic contact dermatitis.
Bäumer W; Sülzle B; Weigt H; De Vries VC; Hecht M; Tschernig T; Kietzmann M
Br J Dermatol; 2005 Jul; 153(1):136-44. PubMed ID: 16029339
[TBL] [Abstract][Full Text] [Related]
8. Effect of orally administered rolipram, a phosphodiesterase 4 inhibitor, on a mouse model of the dermatitis caused by 2,4,6-trinitro-1-chlorobenzene (TNCB)-repeated application.
Harada D; Tsukumo Y; Takashima Y; Manabe H
Eur J Pharmacol; 2006 Feb; 532(1-2):128-37. PubMed ID: 16442096
[TBL] [Abstract][Full Text] [Related]
9. AWD-12-281 (inhaled) (elbion/GlaxoSmithKline).
Gutke HJ; Guse JH; Khobzaoui M; Renukappa-Gutke T; Burnet M
Curr Opin Investig Drugs; 2005 Nov; 6(11):1149-58. PubMed ID: 16312137
[TBL] [Abstract][Full Text] [Related]
10. Pharmacological profile of a novel phosphodiesterase 7A and -4 dual inhibitor, YM-393059, on acute and chronic inflammation models.
Yamamoto S; Sugahara S; Ikeda K; Shimizu Y
Eur J Pharmacol; 2006 Nov; 550(1-3):166-72. PubMed ID: 17010967
[TBL] [Abstract][Full Text] [Related]
11. Effects and mechanisms of aloperine on 2, 4-dinitrofluorobenzene-induced allergic contact dermatitis in BALB/c mice.
Yuan XY; Liu W; Zhang P; Wang RY; Guo JY
Eur J Pharmacol; 2010 Mar; 629(1-3):147-52. PubMed ID: 20006963
[TBL] [Abstract][Full Text] [Related]
12. Topically Administered Janus-Kinase Inhibitors Tofacitinib and Oclacitinib Display Impressive Antipruritic and Anti-Inflammatory Responses in a Model of Allergic Dermatitis.
Fukuyama T; Ehling S; Cook E; Bäumer W
J Pharmacol Exp Ther; 2015 Sep; 354(3):394-405. PubMed ID: 26159873
[TBL] [Abstract][Full Text] [Related]
13. Effect of orally administered KF66490, a phosphodiesterase 4 inhibitor, on dermatitis in mouse models.
Harada D; Takada C; Nosaka Y; Takashima Y; Kobayashi K; Takaba K; Manabe H
Int Immunopharmacol; 2009 Jan; 9(1):55-62. PubMed ID: 18854230
[TBL] [Abstract][Full Text] [Related]
14. Topical nanocrystalline silver cream suppresses inflammatory cytokines and induces apoptosis of inflammatory cells in a murine model of allergic contact dermatitis.
Bhol KC; Schechter PJ
Br J Dermatol; 2005 Jun; 152(6):1235-42. PubMed ID: 15948987
[TBL] [Abstract][Full Text] [Related]
15. The phosphodiesterase type IV inhibitor cilomilast decreases pro-inflammatory cytokine production from primary bronchial epithelial cells in lung transplantation patients.
Murphy DM; Ward C; Forrest IA; Pritchard G; Jones D; Stovold R; Fisher AJ; Cawston TE; Lordan JL; Corris PA
J Heart Lung Transplant; 2006 Dec; 25(12):1436-40. PubMed ID: 17178338
[TBL] [Abstract][Full Text] [Related]
16. Effects of cyclosporin A and cilomilast on activated canine, murine and human keratinocytes.
Bäumer W; Kietzmann M
Vet Dermatol; 2007 Apr; 18(2):107-14. PubMed ID: 17355425
[TBL] [Abstract][Full Text] [Related]
17. Highly selective phosphodiesterase 4 inhibitors for the treatment of allergic skin diseases and psoriasis.
Bäumer W; Hoppmann J; Rundfeldt C; Kietzmann M
Inflamm Allergy Drug Targets; 2007 Mar; 6(1):17-26. PubMed ID: 17352685
[TBL] [Abstract][Full Text] [Related]
18. Suppression of the contact hypersensitivity response following topical exposure to 2-butoxyethanol in female BALB/c mice.
Singh P; Morris B; Zhao S; Blaylock BL
Int J Toxicol; 2002; 21(2):107-14. PubMed ID: 12022630
[TBL] [Abstract][Full Text] [Related]
19. Effects of cilomilast on dendritic cell function in contact sensitivity and dendritic cell migration through skin.
Bäumer W; Tschernig T; Sülzle B; Seegers U; Lührmann A; Kietzmann M
Eur J Pharmacol; 2003 Nov; 481(2-3):271-9. PubMed ID: 14642795
[TBL] [Abstract][Full Text] [Related]
20. Effects of ciclamilast, a new PDE 4 PDE4 inhibitor, on airway hyperresponsiveness, PDE4D expression and airway inflammation in a murine model of asthma.
Deng YM; Xie QM; Tang HF; Sun JG; Deng JF; Chen JQ; Yang SY
Eur J Pharmacol; 2006 Oct; 547(1-3):125-35. PubMed ID: 16956605
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
