BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

418 related articles for article (PubMed ID: 12963636)

  • 1. Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure.
    Oudit GY; Crackower MA; Eriksson U; Sarao R; Kozieradzki I; Sasaki T; Irie-Sasaki J; Gidrewicz D; Rybin VO; Wada T; Steinberg SF; Backx PH; Penninger JM
    Circulation; 2003 Oct; 108(17):2147-52. PubMed ID: 12963636
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeted inhibition of beta-adrenergic receptor kinase-1-associated phosphoinositide-3 kinase activity preserves beta-adrenergic receptor signaling and prolongs survival in heart failure induced by calsequestrin overexpression.
    Perrino C; Naga Prasad SV; Patel M; Wolf MJ; Rockman HA
    J Am Coll Cardiol; 2005 Jun; 45(11):1862-70. PubMed ID: 15936620
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Small heat-shock protein Hsp20 attenuates beta-agonist-mediated cardiac remodeling through apoptosis signal-regulating kinase 1.
    Fan GC; Yuan Q; Song G; Wang Y; Chen G; Qian J; Zhou X; Lee YJ; Ashraf M; Kranias EG
    Circ Res; 2006 Nov; 99(11):1233-42. PubMed ID: 17068291
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphoinositide 3-kinase gamma controls autonomic regulation of the mouse heart through Gi-independent downregulation of cAMP level.
    Alloatti G; Marcantoni A; Levi R; Gallo MP; Del Sorbo L; Patrucco E; Barberis L; Malan D; Azzolino O; Wymann M; Hirsch E; Montrucchio G
    FEBS Lett; 2005 Jan; 579(1):133-40. PubMed ID: 15620702
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphoinositide 3-kinasegamma (PI3Kgamma) controls L-type calcium current (ICa,L) through its positive modulation of type-3 phosphodiesterase (PDE3).
    Marcantoni A; Levi RC; Gallo MP; Hirsch E; Alloatti G
    J Cell Physiol; 2006 Feb; 206(2):329-36. PubMed ID: 16110482
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of PI3Kγ enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress.
    Guo D; Kassiri Z; Basu R; Chow FL; Kandalam V; Damilano F; Liang W; Izumo S; Hirsch E; Penninger JM; Backx PH; Oudit GY
    Circ Res; 2010 Nov; 107(10):1275-89. PubMed ID: 20847309
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of AT1 receptor in isoproterenol-induced cardiac hypertrophy and oxidative stress in mice.
    Zhang GX; Ohmori K; Nagai Y; Fujisawa Y; Nishiyama A; Abe Y; Kimura S
    J Mol Cell Cardiol; 2007 Apr; 42(4):804-11. PubMed ID: 17350036
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy.
    Jaffré F; Bonnin P; Callebert J; Debbabi H; Setola V; Doly S; Monassier L; Mettauer B; Blaxall BC; Launay JM; Maroteaux L
    Circ Res; 2009 Jan; 104(1):113-23. PubMed ID: 19023134
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Celiprolol, a vasodilatory beta-blocker, inhibits pressure overload-induced cardiac hypertrophy and prevents the transition to heart failure via nitric oxide-dependent mechanisms in mice.
    Liao Y; Asakura M; Takashima S; Ogai A; Asano Y; Shintani Y; Minamino T; Asanuma H; Sanada S; Kim J; Kitamura S; Tomoike H; Hori M; Kitakaze M
    Circulation; 2004 Aug; 110(6):692-9. PubMed ID: 15262839
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phospholipase C epsilon modulates beta-adrenergic receptor-dependent cardiac contraction and inhibits cardiac hypertrophy.
    Wang H; Oestreich EA; Maekawa N; Bullard TA; Vikstrom KL; Dirksen RT; Kelley GG; Blaxall BC; Smrcka AV
    Circ Res; 2005 Dec; 97(12):1305-13. PubMed ID: 16293787
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transgenic mice with cardiac-specific over-expression of MLK7 have increased mortality when exposed to chronic beta-adrenergic stimulation.
    Christe M; Jin N; Wang X; Gould KE; Iversen PW; Yu X; Lorenz JN; Kadambi V; Zuckerman SH; Bloem LJ
    J Mol Cell Cardiol; 2004 Sep; 37(3):705-15. PubMed ID: 15350844
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Restoration of beta-adrenergic receptor signaling and contractile function in heart failure by disruption of the betaARK1/phosphoinositide 3-kinase complex.
    Perrino C; Naga Prasad SV; Schroder JN; Hata JA; Milano C; Rockman HA
    Circulation; 2005 May; 111(20):2579-87. PubMed ID: 15897344
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphatase inhibitor-1-deficient mice are protected from catecholamine-induced arrhythmias and myocardial hypertrophy.
    El-Armouche A; Wittköpper K; Degenhardt F; Weinberger F; Didié M; Melnychenko I; Grimm M; Peeck M; Zimmermann WH; Unsöld B; Hasenfuss G; Dobrev D; Eschenhagen T
    Cardiovasc Res; 2008 Dec; 80(3):396-406. PubMed ID: 18689792
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cardiac sarcoplasmic reticulum calcium release and load are enhanced by subcellular cAMP elevations in PI3Kgamma-deficient mice.
    Kerfant BG; Gidrewicz D; Sun H; Oudit GY; Penninger JM; Backx PH
    Circ Res; 2005 May; 96(10):1079-86. PubMed ID: 15860757
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The alarmin cytokine, high mobility group box 1, is produced by viable cardiomyocytes and mediates the lipopolysaccharide-induced myocardial dysfunction via a TLR4/phosphatidylinositol 3-kinase gamma pathway.
    Xu H; Su Z; Wu J; Yang M; Penninger JM; Martin CM; Kvietys PR; Rui T
    J Immunol; 2010 Feb; 184(3):1492-8. PubMed ID: 20028656
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Beta-adrenergic receptor subtype-specific signaling in cardiac myocytes from beta(1) and beta(2) adrenoceptor knockout mice.
    Devic E; Xiang Y; Gould D; Kobilka B
    Mol Pharmacol; 2001 Sep; 60(3):577-83. PubMed ID: 11502890
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Altered heart rate and sinoatrial node function in mice lacking the cAMP regulator phosphoinositide 3-kinase-gamma.
    Rose RA; Kabir MG; Backx PH
    Circ Res; 2007 Dec; 101(12):1274-82. PubMed ID: 17975110
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects.
    Patrucco E; Notte A; Barberis L; Selvetella G; Maffei A; Brancaccio M; Marengo S; Russo G; Azzolino O; Rybalkin SD; Silengo L; Altruda F; Wetzker R; Wymann MP; Lembo G; Hirsch E
    Cell; 2004 Aug; 118(3):375-87. PubMed ID: 15294162
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeted beta-adrenergic receptor kinase (betaARK1) inhibition by gene transfer in failing human hearts.
    Williams ML; Hata JA; Schroder J; Rampersaud E; Petrofski J; Jakoi A; Milano CA; Koch WJ
    Circulation; 2004 Apr; 109(13):1590-3. PubMed ID: 15051637
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphatidylinositol 3-kinase gamma is a critical mediator of myocardial ischemic and adenosine-mediated preconditioning.
    Ban K; Cooper AJ; Samuel S; Bhatti A; Patel M; Izumo S; Penninger JM; Backx PH; Oudit GY; Tsushima RG
    Circ Res; 2008 Sep; 103(6):643-53. PubMed ID: 18688045
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.