These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

88 related articles for article (PubMed ID: 12964883)

  • 1. Microtubule-stabilizing marine metabolite laulimalide and its derivatives: synthetic approaches and antitumor activity.
    Mulzer J; Ohler E
    Chem Rev; 2003 Sep; 103(9):3753-86. PubMed ID: 12964883
    [No Abstract]   [Full Text] [Related]  

  • 2. Synthetic approaches to the microtubule stabilizing agent (-)-laulimalide.
    Crimmins MT
    Curr Opin Drug Discov Devel; 2002 Nov; 5(6):944-59. PubMed ID: 12478725
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro and in vivo anticancer activities of synthetic (-)-laulimalide, a marine natural product microtubule stabilizing agent.
    Liu J; Towle MJ; Cheng H; Saxton P; Reardon C; Wu J; Murphy EA; Kuznetsov G; Johannes CW; Tremblay MR; Zhao H; Pesant M; Fang FG; Vermeulen MW; Gallagher BM; Littlefield BA
    Anticancer Res; 2007; 27(3B):1509-18. PubMed ID: 17595769
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Total synthesis of the microtubule stabilizing antitumor agent laulimalide and some nonnatural analogues: the power of Sharpless' asymmetric epoxidation.
    Ahmed A; Hoegenauer EK; Enev VS; Hanbauer M; Kaehlig H; Ohler E; Mulzer J
    J Org Chem; 2003 Apr; 68(8):3026-42. PubMed ID: 12688769
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Laulimalide and isolaulimalide, new paclitaxel-like microtubule-stabilizing agents.
    Mooberry SL; Tien G; Hernandez AH; Plubrukarn A; Davidson BS
    Cancer Res; 1999 Feb; 59(3):653-60. PubMed ID: 9973214
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Total synthesis of the microtubule-stabilizing agent (-)-laulimalide.
    Paterson I; De Savi C; Tudge M
    Org Lett; 2001 Oct; 3(20):3149-52. PubMed ID: 11574017
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological evaluation of novel, simplified analogues of laulimalide: modification of the side chain.
    Paterson I; Menche D; Håkansson AE; Longstaff A; Wong D; Barasoain I; Buey RM; Díaz JF
    Bioorg Med Chem Lett; 2005 May; 15(9):2243-7. PubMed ID: 15837302
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of the macrocyclic core of laulimalide.
    Paterson I; De Savi C; Tudge M
    Org Lett; 2001 Jan; 3(2):213-6. PubMed ID: 11430037
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Laulimalide and paclitaxel: a comparison of their effects on tubulin assembly and their synergistic action when present simultaneously.
    Gapud EJ; Bai R; Ghosh AK; Hamel E
    Mol Pharmacol; 2004 Jul; 66(1):113-21. PubMed ID: 15213302
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Total synthesis of (-)-laulimalide.
    Wender PA; Hegde SG; Hubbard RD; Zhang L
    J Am Chem Soc; 2002 May; 124(18):4956-7. PubMed ID: 11982349
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Laulimalide and synthetic laulimalide analogues are synergistic with paclitaxel and 2-methoxyestradiol.
    Clark EA; Hills PM; Davidson BS; Wender PA; Mooberry SL
    Mol Pharm; 2006; 3(4):457-67. PubMed ID: 16889440
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Peloruside A does not bind to the taxoid site on beta-tubulin and retains its activity in multidrug-resistant cell lines.
    Gaitanos TN; Buey RM; Díaz JF; Northcote PT; Teesdale-Spittle P; Andreu JM; Miller JH
    Cancer Res; 2004 Aug; 64(15):5063-7. PubMed ID: 15289305
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Peloruside A, a novel antimitotic agent with paclitaxel-like microtubule- stabilizing activity.
    Hood KA; West LM; Rouwé B; Northcote PT; Berridge MV; Wakefield SJ; Miller JH
    Cancer Res; 2002 Jun; 62(12):3356-60. PubMed ID: 12067973
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The microtubule stabilizing agent laulimalide does not bind in the taxoid site, kills cells resistant to paclitaxel and epothilones, and may not require its epoxide moiety for activity.
    Pryor DE; O'Brate A; Bilcer G; Díaz JF; Wang Y; Wang Y; Kabaki M; Jung MK; Andreu JM; Ghosh AK; Giannakakou P; Hamel E
    Biochemistry; 2002 Jul; 41(29):9109-15. PubMed ID: 12119025
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Macrocyclization via allyl transfer: total synthesis of laulimalide.
    Enev VS; Kaehlig H; Mulzer J
    J Am Chem Soc; 2001 Oct; 123(43):10764-5. PubMed ID: 11674020
    [No Abstract]   [Full Text] [Related]  

  • 16. [Natural anti-tumor compounds with activity of promoting microtubule assembly].
    Li YZ; Hu W; Zhou L
    Yao Xue Xue Bao; 2001 Feb; 36(2):155-60. PubMed ID: 12579888
    [No Abstract]   [Full Text] [Related]  

  • 17. Microtubule-stabilizing activity of zampanolide, a potent macrolide isolated from the Tongan marine sponge Cacospongia mycofijiensis.
    Field JJ; Singh AJ; Kanakkanthara A; Halafihi T; Northcote PT; Miller JH
    J Med Chem; 2009 Nov; 52(22):7328-32. PubMed ID: 19877653
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Total synthesis of microtubule-stabilizing agent (-)-laulimalide.
    Ghosh AK; Wang Y; Kim JT
    J Org Chem; 2001 Dec; 66(26):8973-82. PubMed ID: 11749630
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and evaluation of artificial taxoids with antitumor and multi-drug resistance reversing activities.
    Morihira K; Nishimori T; Kusama H; Horiguchi Y; Kuwajima I; Tsuruo T
    Bioorg Med Chem Lett; 1998 Nov; 8(21):2977-82. PubMed ID: 9873658
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modulation of drug resistance in ovarian adenocarcinoma by enhancing intracellular ceramide using tamoxifen-loaded biodegradable polymeric nanoparticles.
    Devalapally H; Duan Z; Seiden MV; Amiji MM
    Clin Cancer Res; 2008 May; 14(10):3193-203. PubMed ID: 18483388
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.