BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 12966028)

  • 41. The presenilin C-terminus is required for ER-retention, nicastrin-binding and gamma-secretase activity.
    Kaether C; Capell A; Edbauer D; Winkler E; Novak B; Steiner H; Haass C
    EMBO J; 2004 Dec; 23(24):4738-48. PubMed ID: 15549135
    [TBL] [Abstract][Full Text] [Related]  

  • 42. A novel transmembrane topology of presenilin based on reconciling experimental and computational evidence.
    Henricson A; Käll L; Sonnhammer EL
    FEBS J; 2005 Jun; 272(11):2727-33. PubMed ID: 15943807
    [TBL] [Abstract][Full Text] [Related]  

  • 43. A signal peptide peptidase (SPP) reporter activity assay based on the cleavage of type II membrane protein substrates provides further evidence for an inverted orientation of the SPP active site relative to presenilin.
    Nyborg AC; Jansen K; Ladd TB; Fauq A; Golde TE
    J Biol Chem; 2004 Oct; 279(41):43148-56. PubMed ID: 15252014
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Impas 1 possesses endoproteolytic activity against multipass membrane protein substrate cleaving the presenilin 1 holoprotein.
    Moliaka YK; Grigorenko A; Madera D; Rogaev EI
    FEBS Lett; 2004 Jan; 557(1-3):185-92. PubMed ID: 14741365
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Targeting presenilin-type aspartic protease signal peptide peptidase with gamma-secretase inhibitors.
    Weihofen A; Lemberg MK; Friedmann E; Rueeger H; Schmitz A; Paganetti P; Rovelli G; Martoglio B
    J Biol Chem; 2003 May; 278(19):16528-33. PubMed ID: 12621027
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Signal peptide peptidase forms a homodimer that is labeled by an active site-directed gamma-secretase inhibitor.
    Nyborg AC; Kornilova AY; Jansen K; Ladd TB; Wolfe MS; Golde TE
    J Biol Chem; 2004 Apr; 279(15):15153-60. PubMed ID: 14704149
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins.
    Friedmann E; Lemberg MK; Weihofen A; Dev KK; Dengler U; Rovelli G; Martoglio B
    J Biol Chem; 2004 Dec; 279(49):50790-8. PubMed ID: 15385547
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Mechanism, specificity, and physiology of signal peptide peptidase (SPP) and SPP-like proteases.
    Voss M; Schröder B; Fluhrer R
    Biochim Biophys Acta; 2013 Dec; 1828(12):2828-39. PubMed ID: 24099004
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Rhomboid proteases: familiar features in unfamiliar phases.
    Amarneh B; Rawson RB
    Mol Cell; 2009 Dec; 36(6):922-3. PubMed ID: 20064458
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Differential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin homologues SPPL2b and SPPL3.
    Krawitz P; Haffner C; Fluhrer R; Steiner H; Schmid B; Haass C
    J Biol Chem; 2005 Nov; 280(47):39515-23. PubMed ID: 15998642
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Signal peptide peptidases: a family of intramembrane-cleaving proteases that cleave type 2 transmembrane proteins.
    Golde TE; Wolfe MS; Greenbaum DC
    Semin Cell Dev Biol; 2009 Apr; 20(2):225-30. PubMed ID: 19429495
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Structural biology of presenilins and signal peptide peptidases.
    Tomita T; Iwatsubo T
    J Biol Chem; 2013 May; 288(21):14673-80. PubMed ID: 23585568
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases.
    Lemberg MK; Menendez J; Misik A; Garcia M; Koth CM; Freeman M
    EMBO J; 2005 Feb; 24(3):464-72. PubMed ID: 15616571
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Latest emerging functions of SPP/SPPL intramembrane proteases.
    Mentrup T; Fluhrer R; Schröder B
    Eur J Cell Biol; 2017 Aug; 96(5):372-382. PubMed ID: 28366434
    [TBL] [Abstract][Full Text] [Related]  

  • 55. The α-helical content of the transmembrane domain of the British dementia protein-2 (Bri2) determines its processing by signal peptide peptidase-like 2b (SPPL2b).
    Fluhrer R; Martin L; Klier B; Haug-Kröper M; Grammer G; Nuscher B; Haass C
    J Biol Chem; 2012 Feb; 287(7):5156-63. PubMed ID: 22194595
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Physiological functions of SPP/SPPL intramembrane proteases.
    Mentrup T; Cabrera-Cabrera F; Fluhrer R; Schröder B
    Cell Mol Life Sci; 2020 Aug; 77(15):2959-2979. PubMed ID: 32052089
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Identification of an archaeal presenilin-like intramembrane protease.
    Torres-Arancivia C; Ross CM; Chavez J; Assur Z; Dolios G; Mancia F; Ubarretxena-Belandia I
    PLoS One; 2010 Sep; 5(9):. PubMed ID: 20927381
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Structure of a presenilin family intramembrane aspartate protease.
    Li X; Dang S; Yan C; Gong X; Wang J; Shi Y
    Nature; 2013 Jan; 493(7430):56-61. PubMed ID: 23254940
    [TBL] [Abstract][Full Text] [Related]  

  • 59. A C-terminal region of signal peptide peptidase defines a functional domain for intramembrane aspartic protease catalysis.
    Narayanan S; Sato T; Wolfe MS
    J Biol Chem; 2007 Jul; 282(28):20172-9. PubMed ID: 17517891
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Signaling Functions of Intramembrane Aspartyl-Proteases.
    Papadopoulou AA; Fluhrer R
    Front Cardiovasc Med; 2020; 7():591787. PubMed ID: 33381526
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.