124 related articles for article (PubMed ID: 12966155)
1. Evaluation of the blood-brain barrier transport, population pharmacokinetics, and brain distribution of benztropine analogs and cocaine using in vitro and in vivo techniques.
Raje S; Cao J; Newman AH; Gao H; Eddington ND
J Pharmacol Exp Ther; 2003 Nov; 307(2):801-8. PubMed ID: 12966155
[TBL] [Abstract][Full Text] [Related]
2. Effects of N-substituted analogs of benztropine: diminished cocaine-like effects in dopamine transporter ligands.
Katz JL; Kopajtic TA; Agoston GE; Newman AH
J Pharmacol Exp Ther; 2004 May; 309(2):650-60. PubMed ID: 14755006
[TBL] [Abstract][Full Text] [Related]
3. Investigation of the potential pharmacokinetic and pharmaco-dynamic drug interaction between AHN 1-055, a potent benztropine analog used for cocaine abuse, and cocaine after dosing in rats using intracerebral microdialysis.
Raje S; Cornish J; Newman AH; Cao J; Katz JL; Eddington ND
Biopharm Drug Dispos; 2006 Jul; 27(5):229-40. PubMed ID: 16586462
[TBL] [Abstract][Full Text] [Related]
4. Place conditioning and locomotor effects of N-substituted, 4',4''-difluorobenztropine analogs in rats.
Li SM; Newman AH; Katz JL
J Pharmacol Exp Ther; 2005 Jun; 313(3):1223-30. PubMed ID: 15743929
[TBL] [Abstract][Full Text] [Related]
5. Population pharmacokinetics, brain distribution, and pharmacodynamics of 2nd generation dopamine transporter selective benztropine analogs developed as potential substitute therapeutics for treatment of cocaine abuse.
Syed SA; Newman AH; Othman AA; Eddington ND
J Pharm Sci; 2008 May; 97(5):1993-2007. PubMed ID: 17879975
[TBL] [Abstract][Full Text] [Related]
6. Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-{2-[bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and benztropine analogs.
Desai RI; Kopajtic TA; French D; Newman AH; Katz JL
J Pharmacol Exp Ther; 2005 Oct; 315(1):397-404. PubMed ID: 16014753
[TBL] [Abstract][Full Text] [Related]
7. Pharmacodynamic assessment of the benztropine analogues AHN-1055 and AHN-2005 using intracerebral microdialysis to evaluate brain dopamine levels and pharmacokinetic/pharmacodynamic modeling.
Raje S; Cornish J; Newman AH; Cao J; Katz JL; Eddington ND
Pharm Res; 2005 Apr; 22(4):603-12. PubMed ID: 15846468
[TBL] [Abstract][Full Text] [Related]
8. Transport, metabolism, and in vivo population pharmacokinetics of the chloro benztropine analogs, a class of compounds extensively evaluated in animal models of drug abuse.
Othman AA; Syed SA; Newman AH; Eddington ND
J Pharmacol Exp Ther; 2007 Jan; 320(1):344-53. PubMed ID: 17003230
[TBL] [Abstract][Full Text] [Related]
9. Applicability of the dopamine and rate hypotheses in explaining the differences in behavioral pharmacology of the chloro-benztropine analogs: studies conducted using intracerebral microdialysis and population pharmacodynamic modeling.
Othman AA; Newman AH; Eddington ND
J Pharmacol Exp Ther; 2007 Aug; 322(2):760-9. PubMed ID: 17519385
[TBL] [Abstract][Full Text] [Related]
10. Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self-administration in rats: comparisons with monoamine uptake inhibitors.
Hiranita T; Soto PL; Newman AH; Katz JL
J Pharmacol Exp Ther; 2009 May; 329(2):677-86. PubMed ID: 19228996
[TBL] [Abstract][Full Text] [Related]
11. Assessment of the influence of histaminergic actions on cocaine-like effects of 3alpha-diphenylmethoxytropane analogs.
Campbell VC; Kopajtic TA; Newman AH; Katz JL
J Pharmacol Exp Ther; 2005 Nov; 315(2):631-40. PubMed ID: 16055673
[TBL] [Abstract][Full Text] [Related]
12. Dopamine transporter binding without cocaine-like behavioral effects: synthesis and evaluation of benztropine analogs alone and in combination with cocaine in rodents.
Katz JL; Agoston GE; Alling KL; Kline RH; Forster MJ; Woolverton WL; Kopajtic TA; Newman AH
Psychopharmacology (Berl); 2001 Apr; 154(4):362-74. PubMed ID: 11349389
[TBL] [Abstract][Full Text] [Related]
13. Structure-activity relationships at monoamine transporters for a series of N-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes: comparative molecular field analysis, synthesis, and pharmacological evaluation.
Kulkarni SS; Grundt P; Kopajtic T; Katz JL; Newman AH
J Med Chem; 2004 Jun; 47(13):3388-98. PubMed ID: 15189035
[TBL] [Abstract][Full Text] [Related]
14. σ Receptor Effects of N-Substituted Benztropine Analogs: Implications for Antagonism of Cocaine Self-Administration.
Hiranita T; Hong WC; Kopajtic T; Katz JL
J Pharmacol Exp Ther; 2017 Jul; 362(1):2-13. PubMed ID: 28442581
[TBL] [Abstract][Full Text] [Related]
15. The stereotypy-inducing effects of N-substituted benztropine analogs alone and in combination with cocaine do not account for their blockade of cocaine self-administration.
Li L; Hiranita T; Hayashi S; Newman AH; Katz JL
Psychopharmacology (Berl); 2013 Feb; 225(3):733-42. PubMed ID: 22975727
[TBL] [Abstract][Full Text] [Related]
16. Determination of the benztropine analog AHN-1055, a dopamine uptake inhibitor, in rat plasma and brain by high-performance liquid chromatography with ultraviolet absorbance detection.
Raje S; Dowling TC; Eddington ND
J Chromatogr B Analyt Technol Biomed Life Sci; 2002 Mar; 768(2):305-13. PubMed ID: 11888059
[TBL] [Abstract][Full Text] [Related]
17. 3'- and 4'-chloro-substituted analogs of benztropine: intravenous self-administration and in vitro radioligand binding studies in rhesus monkeys.
Woolverton WL; Rowlett JK; Wilcox KM; Paul IA; Kline RH; Newman AH; Katz JL
Psychopharmacology (Berl); 2000 Jan; 147(4):426-35. PubMed ID: 10672637
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and monoamine transporter affinity of 2beta-carbomethoxy-3beta-(4'-p-substituted phenyl)-piperidine analogs of cocaine.
Bois F; Baldwin RM; Kula NS; Baldessarini RJ; Al Tikriti M; Innis RB; Tamagnan GD
Bioorg Med Chem Lett; 2006 Oct; 16(19):5222-5. PubMed ID: 16908151
[TBL] [Abstract][Full Text] [Related]
19. Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine.
Chen N; Zhen J; Reith ME
J Neurochem; 2004 May; 89(4):853-64. PubMed ID: 15140185
[TBL] [Abstract][Full Text] [Related]
20. Effects of 4'-chloro-3 alpha-(diphenylmethoxy)-tropane on mesostriatal, mesocortical, and mesolimbic dopamine transmission: comparison with effects of cocaine.
Tanda G; Ebbs A; Newman AH; Katz JL
J Pharmacol Exp Ther; 2005 May; 313(2):613-20. PubMed ID: 15681658
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]