216 related articles for article (PubMed ID: 12966366)
1. Aceclofenac spares cyclooxygenase 1 as a result of limited but sustained biotransformation to diclofenac.
Hinz B; Rau T; Auge D; Werner U; Ramer R; Rietbrock S; Brune K
Clin Pharmacol Ther; 2003 Sep; 74(3):222-35. PubMed ID: 12966366
[TBL] [Abstract][Full Text] [Related]
2. In vitro effects of aceclofenac and its metabolites on the production by chondrocytes of inflammatory mediators.
Henrotin Y; de Leval X; Mathy-Hartet M; Mouithys-Mickalad A; Deby-Dupont G; Dogné JM; Delarge J; Reginster JY
Inflamm Res; 2001 Aug; 50(8):391-9. PubMed ID: 11556519
[TBL] [Abstract][Full Text] [Related]
3. Aceclofenac blocks prostaglandin E2 production following its intracellular conversion into cyclooxygenase inhibitors.
Yamazaki R; Kawai S; Matsuzaki T; Kaneda N; Hashimoto S; Yokokura T; Okamoto R; Koshino T; Mizushima Y
Eur J Pharmacol; 1997 Jun; 329(2-3):181-7. PubMed ID: 9226412
[TBL] [Abstract][Full Text] [Related]
4. Hydrolytic activity is essential for aceclofenac to inhibit cyclooxygenase in rheumatoid synovial cells.
Yamazaki R; Kawai S; Matsumoto T; Matsuzaki T; Hashimoto S; Yokokura T; Okamoto R; Koshino T; Mizushima Y
J Pharmacol Exp Ther; 1999 May; 289(2):676-81. PubMed ID: 10215639
[TBL] [Abstract][Full Text] [Related]
5. Development of an in-vitro test system for the evaluation of cyclooxygenase-2 inhibitors.
Laufer S; Zechmeister P; Klein T
Inflamm Res; 1999 Mar; 48(3):133-8. PubMed ID: 10219655
[TBL] [Abstract][Full Text] [Related]
6. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.
Riendeau D; Percival MD; Boyce S; Brideau C; Charleson S; Cromlish W; Ethier D; Evans J; Falgueyret JP; Ford-Hutchinson AW; Gordon R; Greig G; Gresser M; Guay J; Kargman S; Léger S; Mancini JA; O'Neill G; Ouellet M; Rodger IW; Thérien M; Wang Z; Webb JK; Wong E; Chan CC
Br J Pharmacol; 1997 May; 121(1):105-17. PubMed ID: 9146894
[TBL] [Abstract][Full Text] [Related]
7. Ex vivo assay to determine the cyclooxygenase selectivity of non-steroidal anti-inflammatory drugs.
Giuliano F; Warner TD
Br J Pharmacol; 1999 Apr; 126(8):1824-30. PubMed ID: 10372826
[TBL] [Abstract][Full Text] [Related]
8. Dose-dependent inhibition of platelet cyclooxygenase-1 and monocyte cyclooxygenase-2 by meloxicam in healthy subjects.
Panara MR; Renda G; Sciulli MG; Santini G; Di Giamberardino M; Rotondo MT; Tacconelli S; Seta F; Patrono C; Patrignani P
J Pharmacol Exp Ther; 1999 Jul; 290(1):276-80. PubMed ID: 10381787
[TBL] [Abstract][Full Text] [Related]
9. Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2.
Esser R; Berry C; Du Z; Dawson J; Fox A; Fujimoto RA; Haston W; Kimble EF; Koehler J; Peppard J; Quadros E; Quintavalla J; Toscano K; Urban L; van Duzer J; Zhang X; Zhou S; Marshall PJ
Br J Pharmacol; 2005 Feb; 144(4):538-50. PubMed ID: 15655513
[TBL] [Abstract][Full Text] [Related]
10. Simultaneous determination of aceclofenac and three of its metabolites in human plasma by high-performance liquid chromatography.
Hinz B; Auge D; Rau T; Rietbrock S; Brune K; Werner U
Biomed Chromatogr; 2003 Jun; 17(4):268-75. PubMed ID: 12833392
[TBL] [Abstract][Full Text] [Related]
11. Limitation of the in vitro whole blood assay for predicting the COX selectivity of NSAIDs in clinical use.
Blain H; Boileau C; Lapicque F; Nédélec E; Loeuille D; Guillaume C; Gaucher A; Jeandel C; Netter P; Jouzeau JY
Br J Clin Pharmacol; 2002 Mar; 53(3):255-65. PubMed ID: 11874389
[TBL] [Abstract][Full Text] [Related]
12. Effects of Tripterygium wilfordii hook F extracts on induction of cyclooxygenase 2 activity and prostaglandin E2 production.
Tao X; Schulze-Koops H; Ma L; Cai J; Mao Y; Lipsky PE
Arthritis Rheum; 1998 Jan; 41(1):130-8. PubMed ID: 9433878
[TBL] [Abstract][Full Text] [Related]
13. Pharmacokinetics of diclofenac and inhibition of cyclooxygenases 1 and 2: no relationship to the CYP2C9 genetic polymorphism in humans.
Kirchheiner J; Meineke I; Steinbach N; Meisel C; Roots I; Brockmöller J
Br J Clin Pharmacol; 2003 Jan; 55(1):51-61. PubMed ID: 12534640
[TBL] [Abstract][Full Text] [Related]
14. In vitro and in vivo pharmacological evidence of selective cyclooxygenase-2 inhibition by nimesulide: an overview.
Famaey JP
Inflamm Res; 1997 Nov; 46(11):437-46. PubMed ID: 9427063
[TBL] [Abstract][Full Text] [Related]
15. Effects of intravenous administration of FR122047 (a selective cyclooxygenase 1 inhibitor) and FR188582 (a selective cyclooxygenase 2 inhibitor) on prostaglandin-E2-induced aqueous flare elevation in pigmented rabbits.
Abe T; Hayasaka Y; Zhang XY; Hayasaka S
Ophthalmic Res; 2004; 36(6):321-6. PubMed ID: 15627832
[TBL] [Abstract][Full Text] [Related]
16. Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers.
Van Hecken A; Schwartz JI; Depré M; De Lepeleire I; Dallob A; Tanaka W; Wynants K; Buntinx A; Arnout J; Wong PH; Ebel DL; Gertz BJ; De Schepper PJ
J Clin Pharmacol; 2000 Oct; 40(10):1109-20. PubMed ID: 11028250
[TBL] [Abstract][Full Text] [Related]
17. Determination of expression of cyclooxygenase-1 and -2 isozymes in canine tissues and their differential sensitivity to nonsteroidal anti-inflammatory drugs.
Wilson JE; Chandrasekharan NV; Westover KD; Eager KB; Simmons DL
Am J Vet Res; 2004 Jun; 65(6):810-8. PubMed ID: 15198222
[TBL] [Abstract][Full Text] [Related]
18. Cyclooxygenase-2 is expressed in neuroblastoma, and nonsteroidal anti-inflammatory drugs induce apoptosis and inhibit tumor growth in vivo.
Johnsen JI; Lindskog M; Ponthan F; Pettersen I; Elfman L; Orrego A; Sveinbjörnsson B; Kogner P
Cancer Res; 2004 Oct; 64(20):7210-5. PubMed ID: 15492235
[TBL] [Abstract][Full Text] [Related]
19. In-vitro test system for the evaluation of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) inhibitors based on a single HPLC run with UV detection using bovine aortic coronary endothelial cells (BAECs).
Dannhardt G; Ulbrich H
Inflamm Res; 2001 May; 50(5):262-9. PubMed ID: 11409489
[TBL] [Abstract][Full Text] [Related]
20. The effect of cyclooxygenase inhibitor diclofenac on experimental murine colon carcinoma.
Falkowski M; Skogstad S; Shahzidi S; Smedsröd B; Sveinbjörnsson B
Anticancer Res; 2003; 23(3B):2303-8. PubMed ID: 12894507
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
