BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 12972416)

  • 1. Methylmalonic acid, a biochemical hallmark of methylmalonic acidurias but no inhibitor of mitochondrial respiratory chain.
    Kölker S; Schwab M; Hörster F; Sauer S; Hinz A; Wolf NI; Mayatepek E; Hoffmann GF; Smeitink JA; Okun JG
    J Biol Chem; 2003 Nov; 278(48):47388-93. PubMed ID: 12972416
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Neurodegeneration in methylmalonic aciduria involves inhibition of complex II and the tricarboxylic acid cycle, and synergistically acting excitotoxicity.
    Okun JG; Hörster F; Farkas LM; Feyh P; Hinz A; Sauer S; Hoffmann GF; Unsicker K; Mayatepek E; Kölker S
    J Biol Chem; 2002 Apr; 277(17):14674-80. PubMed ID: 11847233
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Secondary mitochondrial dysfunction in propionic aciduria: a pathogenic role for endogenous mitochondrial toxins.
    Schwab MA; Sauer SW; Okun JG; Nijtmans LG; Rodenburg RJ; van den Heuvel LP; Dröse S; Brandt U; Hoffmann GF; Ter Laak H; Kölker S; Smeitink JA
    Biochem J; 2006 Aug; 398(1):107-12. PubMed ID: 16686602
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neurodegeneration and chronic renal failure in methylmalonic aciduria--a pathophysiological approach.
    Morath MA; Okun JG; Müller IB; Sauer SW; Hörster F; Hoffmann GF; Kölker S
    J Inherit Metab Dis; 2008 Feb; 31(1):35-43. PubMed ID: 17846917
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 2-Methylcitric acid impairs glutamate metabolism and induces permeability transition in brain mitochondria.
    Amaral AU; Cecatto C; Castilho RF; Wajner M
    J Neurochem; 2016 Apr; 137(1):62-75. PubMed ID: 26800654
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tricarboxylic acid cycle enzyme activities in a mouse model of methylmalonic aciduria.
    Wongkittichote P; Cunningham G; Summar ML; Pumbo E; Forny P; Baumgartner MR; Chapman KA
    Mol Genet Metab; 2019 Dec; 128(4):444-451. PubMed ID: 31648943
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Methylmalonic acid--an endogenous toxin?
    Kölker S; Okun JG
    Cell Mol Life Sci; 2005 Mar; 62(6):621-4. PubMed ID: 15770414
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Long-term exposure of human proximal tubule cells to hydroxycobalamin[c-lactam] as a possible model to study renal disease in methylmalonic acidurias.
    Sauer SW; Opp S; Haarmann A; Okun JG; Kölker S; Morath MA
    J Inherit Metab Dis; 2009 Dec; 32(6):720-727. PubMed ID: 19816787
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolic response to carnitine in methylmalonic aciduria. An effective strategy for elimination of propionyl groups.
    Roe CR; Hoppel CL; Stacey TE; Chalmers RA; Tracey BM; Millington DS
    Arch Dis Child; 1983 Nov; 58(11):916-20. PubMed ID: 6651329
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multiple OXPHOS deficiency in the liver of a patient with CblA methylmalonic aciduria sensitive to vitamin B(12).
    Valayannopoulos V; Hubert L; Benoist JF; Romano S; Arnoux JB; Chrétien D; Kaplan J; Fakhouri F; Rabier D; Rötig A; Lebre AS; Munnich A; de Keyzer Y; de Lonlay P
    J Inherit Metab Dis; 2009 Apr; 32(2):159-62. PubMed ID: 19277894
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Combined malonic and methylmalonic aciduria with normal malonyl-coenzyme A decarboxylase activity: a case supporting multiple aetiologies.
    Gregg AR; Warman AW; Thorburn DR; O'Brien WE
    J Inherit Metab Dis; 1998 Jun; 21(4):382-90. PubMed ID: 9700595
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential inhibitory effects of methylmalonic acid on respiratory chain complex activities in rat tissues.
    Pettenuzzo LF; Ferreira Gda C; Schmidt AL; Dutra-Filho CS; Wyse AT; Wajner M
    Int J Dev Neurosci; 2006 Feb; 24(1):45-52. PubMed ID: 16324816
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Contribution of odd-numbered fatty acid oxidation to propionate production in neonates with methylmalonic and propionic acidaemias.
    Wendel U; Zass R; Leupold D
    Eur J Pediatr; 1993 Dec; 152(12):1021-3. PubMed ID: 8131803
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Malonyl coenzyme A decarboxylase deficiency.
    Brown GK; Scholem RD; Bankier A; Danks DM
    J Inherit Metab Dis; 1984; 7(1):21-6. PubMed ID: 6145813
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitochondrial energy metabolism in neurodegeneration associated with methylmalonic acidemia.
    Melo DR; Kowaltowski AJ; Wajner M; Castilho RF
    J Bioenerg Biomembr; 2011 Feb; 43(1):39-46. PubMed ID: 21271280
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Possible explanation for hyperglycinaemia in propionic acidaemia and methylmalonic acidaemia: propionate and methylmalonate inhibit liver and brain mitochondrial clycine transport.
    Ugarte M; Lopez-Lahoya J; Garcia ML; Benavides J; Valdivieso F
    J Inherit Metab Dis; 1980; 2(4):93-9. PubMed ID: 6796767
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Deleterious action of FA metabolites on ATP synthesis: possible link between lipotoxicity, mitochondrial dysfunction, and insulin resistance.
    Abdul-Ghani MA; Muller FL; Liu Y; Chavez AO; Balas B; Zuo P; Chang Z; Tripathy D; Jani R; Molina-Carrion M; Monroy A; Folli F; Van Remmen H; DeFronzo RA
    Am J Physiol Endocrinol Metab; 2008 Sep; 295(3):E678-85. PubMed ID: 18593850
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential inhibitory effect of long-chain acyl-CoA esters on succinate and glutamate transport into rat liver mitochondria and its possible implications for long-chain fatty acid oxidation defects.
    Ventura FV; Ruiter J; Ijlst L; de Almeida IT; Wanders RJ
    Mol Genet Metab; 2005 Nov; 86(3):344-52. PubMed ID: 16176879
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Methylcitric acid determination in amniotic fluid by electron-impact mass fragmentography.
    Kretschmer RE; Bachmann C
    J Clin Chem Clin Biochem; 1988 May; 26(5):345-8. PubMed ID: 3404093
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Effect of Methylmalonic Acid Treatment on Human Neuronal Cell Coenzyme Q
    Proctor EC; Turton N; Boan EJ; Bennett E; Philips S; Heaton RA; Hargreaves IP
    Int J Mol Sci; 2020 Nov; 21(23):. PubMed ID: 33266298
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.