BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

665 related articles for article (PubMed ID: 12975486)

  • 1. Identification of novel isoform-selective inhibitors within class I histone deacetylases.
    Hu E; Dul E; Sung CM; Chen Z; Kirkpatrick R; Zhang GF; Johanson K; Liu R; Lago A; Hofmann G; Macarron R; de los Frailes M; Perez P; Krawiec J; Winkler J; Jaye M
    J Pharmacol Exp Ther; 2003 Nov; 307(2):720-8. PubMed ID: 12975486
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors.
    Khan N; Jeffers M; Kumar S; Hackett C; Boldog F; Khramtsov N; Qian X; Mills E; Berghs SC; Carey N; Finn PW; Collins LS; Tumber A; Ritchie JW; Jensen PB; Lichenstein HS; Sehested M
    Biochem J; 2008 Jan; 409(2):581-9. PubMed ID: 17868033
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression and functional characterization of recombinant human HDAC1 and HDAC3.
    Li J; Staver MJ; Curtin ML; Holms JH; Frey RR; Edalji R; Smith R; Michaelides MR; Davidsen SK; Glaser KB
    Life Sci; 2004 Apr; 74(22):2693-705. PubMed ID: 15043985
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Toward selective histone deacetylase inhibitor design: homology modeling, docking studies, and molecular dynamics simulations of human class I histone deacetylases.
    Wang DF; Helquist P; Wiech NL; Wiest O
    J Med Chem; 2005 Nov; 48(22):6936-47. PubMed ID: 16250652
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3.
    Thangaraju M; Carswell KN; Prasad PD; Ganapathy V
    Biochem J; 2009 Jan; 417(1):379-89. PubMed ID: 18789002
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation.
    Liu HL; Chen Y; Cui GH; Zhou JF
    Acta Pharmacol Sin; 2005 May; 26(5):603-9. PubMed ID: 15842781
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation.
    Park JH; Jung Y; Kim TY; Kim SG; Jong HS; Lee JW; Kim DK; Lee JS; Kim NK; Kim TY; Bang YJ
    Clin Cancer Res; 2004 Aug; 10(15):5271-81. PubMed ID: 15297431
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: specific role of class I histone deacetylases in vitro and in vivo.
    Weichert W; Röske A; Niesporek S; Noske A; Buckendahl AC; Dietel M; Gekeler V; Boehm M; Beckers T; Denkert C
    Clin Cancer Res; 2008 Mar; 14(6):1669-77. PubMed ID: 18347167
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Competitive inhibition of histone deacetylase activity by trichostatin A and butyrate.
    Sekhavat A; Sun JM; Davie JR
    Biochem Cell Biol; 2007 Dec; 85(6):751-8. PubMed ID: 18059533
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Antiproliferative and proapoptotic effects of histone deacetylase inhibitors on gastrointestinal neuroendocrine tumor cells.
    Baradari V; Huether A; Höpfner M; Schuppan D; Scherübl H
    Endocr Relat Cancer; 2006 Dec; 13(4):1237-50. PubMed ID: 17158768
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kinetics and comparative reactivity of human class I and class IIb histone deacetylases.
    Schultz BE; Misialek S; Wu J; Tang J; Conn MT; Tahilramani R; Wong L
    Biochemistry; 2004 Aug; 43(34):11083-91. PubMed ID: 15323567
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The histone deacetylase inhibitors suberoylanilide hydroxamic (Vorinostat) and valproic acid induce irreversible and MDR1-independent resistance in human colon cancer cells.
    Fedier A; Dedes KJ; Imesch P; Von Bueren AO; Fink D
    Int J Oncol; 2007 Sep; 31(3):633-41. PubMed ID: 17671692
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative molecular dynamics simulations of histone deacetylase-like protein: binding modes and free energy analysis to hydroxamic acid inhibitors.
    Yan C; Xiu Z; Li X; Li S; Hao C; Teng H
    Proteins; 2008 Oct; 73(1):134-49. PubMed ID: 18398905
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Histone deacetylase inhibitor-induced cellular apoptosis involves stanniocalcin-1 activation.
    Law AY; Lai KP; Lui WC; Wan HT; Wong CK
    Exp Cell Res; 2008 Oct; 314(16):2975-84. PubMed ID: 18652825
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Histone deacetylase 3 represses HTLV-1 tax transcription.
    Villanueva R; Iglesias AH; Camelo S; Sanin LC; Gray SG; Dangond F
    Oncol Rep; 2006 Sep; 16(3):581-5. PubMed ID: 16865259
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and evaluation of 'Linkerless' hydroxamic acids as selective HDAC8 inhibitors.
    Krennhrubec K; Marshall BL; Hedglin M; Verdin E; Ulrich SM
    Bioorg Med Chem Lett; 2007 May; 17(10):2874-8. PubMed ID: 17346959
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-alkylamides as a new class of synthetic histone deacetylase inhibitors. 1. Design, synthesis, biological evaluation, and binding mode studies performed through three different docking procedures.
    Mai A; Massa S; Ragno R; Cerbara I; Jesacher F; Loidl P; Brosch G
    J Med Chem; 2003 Feb; 46(4):512-24. PubMed ID: 12570373
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The novel histone deacetylase inhibitor BL1521 inhibits proliferation and induces apoptosis in neuroblastoma cells.
    de Ruijter AJ; Kemp S; Kramer G; Meinsma RJ; Kaufmann JO; Caron HN; van Kuilenburg AB
    Biochem Pharmacol; 2004 Oct; 68(7):1279-88. PubMed ID: 15345317
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Endogenous inhibition of histone deacetylase 1 by tumor-suppressive maspin.
    Li X; Yin S; Meng Y; Sakr W; Sheng S
    Cancer Res; 2006 Sep; 66(18):9323-9. PubMed ID: 16982778
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Histone deacetylase inhibitors induce apoptosis, histone hyperacetylation and up-regulation of gene transcription in Schistosoma mansoni.
    Dubois F; Caby S; Oger F; Cosseau C; Capron M; Grunau C; Dissous C; Pierce RJ
    Mol Biochem Parasitol; 2009 Nov; 168(1):7-15. PubMed ID: 19538992
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.