284 related articles for article (PubMed ID: 12975488)
1. Chemoattractant receptor-homologous molecule expressed on Th2 cells activation in vivo increases blood leukocyte counts and its blockade abrogates 13,14-dihydro-15-keto-prostaglandin D2-induced eosinophilia in rats.
Shichijo M; Sugimoto H; Nagao K; Inbe H; Encinas JA; Takeshita K; Bacon KB; Gantner F
J Pharmacol Exp Ther; 2003 Nov; 307(2):518-25. PubMed ID: 12975488
[TBL] [Abstract][Full Text] [Related]
2. Differential modulation of human basophil functions through prostaglandin D2 receptors DP and chemoattractant receptor-homologous molecule expressed on Th2 cells/DP2.
Yoshimura-Uchiyama C; Iikura M; Yamaguchi M; Nagase H; Ishii A; Matsushima K; Yamamoto K; Shichijo M; Bacon KB; Hirai K
Clin Exp Allergy; 2004 Aug; 34(8):1283-90. PubMed ID: 15298571
[TBL] [Abstract][Full Text] [Related]
3. Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation.
Uller L; Mathiesen JM; Alenmyr L; Korsgren M; Ulven T; Högberg T; Andersson G; Persson CG; Kostenis E
Respir Res; 2007 Feb; 8(1):16. PubMed ID: 17328802
[TBL] [Abstract][Full Text] [Related]
4. Pharmacologic profile of OC000459, a potent, selective, and orally active D prostanoid receptor 2 antagonist that inhibits mast cell-dependent activation of T helper 2 lymphocytes and eosinophils.
Pettipher R; Vinall SL; Xue L; Speight G; Townsend ER; Gazi L; Whelan CJ; Armer RE; Payton MA; Hunter MG
J Pharmacol Exp Ther; 2012 Feb; 340(2):473-82. PubMed ID: 22106101
[TBL] [Abstract][Full Text] [Related]
5. Effects of prostaglandin D2, 15-deoxy-Delta12,14-prostaglandin J2, and selective DP1 and DP2 receptor agonists on pulmonary infiltration of eosinophils in Brown Norway rats.
Almishri W; Cossette C; Rokach J; Martin JG; Hamid Q; Powell WS
J Pharmacol Exp Ther; 2005 Apr; 313(1):64-9. PubMed ID: 15590767
[TBL] [Abstract][Full Text] [Related]
6. Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor.
Shiraishi Y; Asano K; Nakajima T; Oguma T; Suzuki Y; Shiomi T; Sayama K; Niimi K; Wakaki M; Kagyo J; Ikeda E; Hirai H; Yamaguchi K; Ishizaka A
J Pharmacol Exp Ther; 2005 Mar; 312(3):954-60. PubMed ID: 15528449
[TBL] [Abstract][Full Text] [Related]
7. An orally bioavailable small molecule antagonist of CRTH2, ramatroban (BAY u3405), inhibits prostaglandin D2-induced eosinophil migration in vitro.
Sugimoto H; Shichijo M; Iino T; Manabe Y; Watanabe A; Shimazaki M; Gantner F; Bacon KB
J Pharmacol Exp Ther; 2003 Apr; 305(1):347-52. PubMed ID: 12649388
[TBL] [Abstract][Full Text] [Related]
8. Inhibitory effect of the 4-aminotetrahydroquinoline derivatives, selective chemoattractant receptor-homologous molecule expressed on T helper 2 cell antagonists, on eosinophil migration induced by prostaglandin D2.
Mimura H; Ikemura T; Kotera O; Sawada M; Tashiro S; Fuse E; Ueno K; Manabe H; Ohshima E; Karasawa A; Miyaji H
J Pharmacol Exp Ther; 2005 Jul; 314(1):244-51. PubMed ID: 15798001
[TBL] [Abstract][Full Text] [Related]
9. Evidence that 13-14 di-hydro, 15-keto prostaglandin D(2)-induced airway eosinophilia in guinea-pigs is independent of interleukin-5.
Whelan CJ
Inflamm Res; 2009 Feb; 58(2):103-8. PubMed ID: 19184361
[TBL] [Abstract][Full Text] [Related]
10. A dominant role for chemoattractant receptor-homologous molecule expressed on T helper type 2 (Th2) cells (CRTH2) in mediating chemotaxis of CRTH2+ CD4+ Th2 lymphocytes in response to mast cell supernatants.
Gyles SL; Xue L; Townsend ER; Wettey F; Pettipher R
Immunology; 2006 Nov; 119(3):362-8. PubMed ID: 17067313
[TBL] [Abstract][Full Text] [Related]
11. Prostaglandin D2 causes preferential induction of proinflammatory Th2 cytokine production through an action on chemoattractant receptor-like molecule expressed on Th2 cells.
Xue L; Gyles SL; Wettey FR; Gazi L; Townsend E; Hunter MG; Pettipher R
J Immunol; 2005 Nov; 175(10):6531-6. PubMed ID: 16272307
[TBL] [Abstract][Full Text] [Related]
12. Expression and molecular pharmacology of the mouse CRTH2 receptor.
Hata AN; Zent R; Breyer MD; Breyer RM
J Pharmacol Exp Ther; 2003 Aug; 306(2):463-70. PubMed ID: 12721327
[TBL] [Abstract][Full Text] [Related]
13. Prostaglandin H2 induces the migration of human eosinophils through the chemoattractant receptor homologous molecule of Th2 cells, CRTH2.
Schuligoi R; Sedej M; Waldhoer M; Vukoja A; Sturm EM; Lippe IT; Peskar BA; Heinemann A
J Leukoc Biol; 2009 Jan; 85(1):136-45. PubMed ID: 18835884
[TBL] [Abstract][Full Text] [Related]
14. Selective expression of a novel surface molecule by human Th2 cells in vivo.
Nagata K; Tanaka K; Ogawa K; Kemmotsu K; Imai T; Yoshie O; Abe H; Tada K; Nakamura M; Sugamura K; Takano S
J Immunol; 1999 Feb; 162(3):1278-86. PubMed ID: 9973380
[TBL] [Abstract][Full Text] [Related]
15. Antagonists of the prostaglandin D2 receptor CRTH2.
Pettipher R; Hansel TT
Drug News Perspect; 2008; 21(6):317-22. PubMed ID: 18836589
[TBL] [Abstract][Full Text] [Related]
16. Pharmacological characterization of guinea pig chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2).
Liu F; Gonzalo JA; Manning S; O'Connell LE; Fedyk ER; Burke KE; Elder AM; Pulido JC; Cao W; Tayber O; Qiu Y; Ghosh S; Ocain TD; Hodge MR; Suzuki-Yagawa Y
Prostaglandins Other Lipid Mediat; 2005 May; 76(1-4):133-47. PubMed ID: 15967168
[TBL] [Abstract][Full Text] [Related]
17. A novel antagonist of prostaglandin D2 blocks the locomotion of eosinophils and basophils.
Royer JF; Schratl P; Carrillo JJ; Jupp R; Barker J; Weyman-Jones C; Beri R; Sargent C; Schmidt JA; Lang-Loidolt D; Heinemann A
Eur J Clin Invest; 2008 Sep; 38(9):663-71. PubMed ID: 18837743
[TBL] [Abstract][Full Text] [Related]
18. Identification of indole derivatives exclusively interfering with a G protein-independent signaling pathway of the prostaglandin D2 receptor CRTH2.
Mathiesen JM; Ulven T; Martini L; Gerlach LO; Heinemann A; Kostenis E
Mol Pharmacol; 2005 Aug; 68(2):393-402. PubMed ID: 15870392
[TBL] [Abstract][Full Text] [Related]
19. 15R-methyl-prostaglandin D2 is a potent and selective CRTH2/DP2 receptor agonist in human eosinophils.
Monneret G; Cossette C; Gravel S; Rokach J; Powell WS
J Pharmacol Exp Ther; 2003 Jan; 304(1):349-55. PubMed ID: 12490611
[TBL] [Abstract][Full Text] [Related]
20. Delta12-prostaglandin D2 is a potent and selective CRTH2 receptor agonist and causes activation of human eosinophils and Th2 lymphocytes.
Gazi L; Gyles S; Rose J; Lees S; Allan C; Xue L; Jassal R; Speight G; Gamble V; Pettipher R
Prostaglandins Other Lipid Mediat; 2005 Jan; 75(1-4):153-67. PubMed ID: 15789622
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
