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3. Hematological effects of certain 2,4-diaminopyrimidines, antagonists of folic acid metabolism. HAMILTON L; PHILIPS FS; STERNBERG SS; CLARKE DA; HITCHINGS GH Blood; 1954 Nov; 9(11):1062-81. PubMed ID: 13208758 [No Abstract] [Full Text] [Related]
4. 2,4-diaminopyrimidines. The cyclization of 6-phenacylthio and related derivatives to thieno[2,3-d]pyrimidines and thiazolo[3,2-c]pyrimidines. Roth B J Med Chem; 1969 Mar; 12(2):227-32. PubMed ID: 4306482 [No Abstract] [Full Text] [Related]
5. Synthesis of some bis(2,4-diaminopyrimidines) and bis(2,4-diaminoquinazolines) as potential antimalarial agents. Hynes JB; Gratz RF; Ashton WT J Med Chem; 1972 Dec; 15(12):1332-3. PubMed ID: 4629015 [No Abstract] [Full Text] [Related]
7. Selective inhibition of Leishmania dihydrofolate reductase and Leishmania growth by 5-benzyl-2,4-diaminopyrimidines. Sirawaraporn W; Sertsrivanich R; Booth RG; Hansch C; Neal RA; Santi DV Mol Biochem Parasitol; 1988 Oct; 31(1):79-85. PubMed ID: 3185614 [TBL] [Abstract][Full Text] [Related]
8. 2,4-Diaminothieno(2,3-d)pyrimidines as antifolates and antimalarials. 3. Synthesis of 5,6-disubstituted derivatives and related tetracyclic analogs. Rosowsky A; Chen KK; Lin M J Med Chem; 1973 Mar; 16(3):191-4. PubMed ID: 4632695 [No Abstract] [Full Text] [Related]
9. PREPARATION AND GROWTH-INHIBITORY PROPERTIES OF NEW POLYCYCLIC 2,4-DIAMINOPYRIMIDINES. MODEST EJ; CHATTERJEE S; FOLEY GE; FARBER S Acta Unio Int Contra Cancrum; 1964; 20():112-4. PubMed ID: 14151862 [No Abstract] [Full Text] [Related]
10. 2,4-Diaminothieno(2,3-d)pyrimidines as antifolates and antimalarials. 2. Synthesis of 2,4-diaminopyrido(4',3':4,5)thieno(2,3-d)pyrimidines and 2,4-diamino-8H-thiopyrano(4',3':4,5)thieno(2,3-d)pyrimidines. Chaykovsky M; Lin M; Rosowsky A; Modest EJ J Med Chem; 1973 Mar; 16(3):188-91. PubMed ID: 4632694 [No Abstract] [Full Text] [Related]
11. Quantitative structure-activity relationships of antimalarial and dihydrofolate reductase inhibition by quinazolines and 5-substituted benzyl-2,4-diaminopyrimidines. Hansch C; Fukunaga JY; Jow PY J Med Chem; 1977 Jan; 20(1):96-102. PubMed ID: 319234 [TBL] [Abstract][Full Text] [Related]
12. 2,4-Diaminothieno(2,3-d)pyrimidines as antifolates and antimalarials. 1. Synthesis of 2,4-diamino-5,6,7,8-tetrahydrothianaphthena(2,3-d)pyrimidines and related compounds. Rosowsky A; Chaykovsky M; Chen KK; Lin M; Modest EJ J Med Chem; 1973 Mar; 16(3):185-8. PubMed ID: 4632693 [No Abstract] [Full Text] [Related]
13. The development of the diaminopyrimidines. Burchall JJ J Antimicrob Chemother; 1979 Nov; 5(B):3-14. PubMed ID: 395152 [No Abstract] [Full Text] [Related]
14. Inhibition of nucleic acid synthesis by folic acid antagonists. SKIPPER HE; MITCHELL JH; BENNETT LL Cancer Res; 1950 Aug; 10(8):510-2. PubMed ID: 15434808 [No Abstract] [Full Text] [Related]
15. Partial reversal of the antileukemic action of folic acid antagonists by nucleic acids. SKIPPER HE; BELL M; CHAPMAN JB Cancer; 1951 Mar; 4(2):357-9. PubMed ID: 14821931 [No Abstract] [Full Text] [Related]
16. Application of neural networks: quantitative structure-activity relationships of the derivatives of 2,4-diamino-5-(substituted-benzyl)pyrimidines as DHFR inhibitors. So SS; Richards WG J Med Chem; 1992 Aug; 35(17):3201-7. PubMed ID: 1507206 [TBL] [Abstract][Full Text] [Related]
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18. Triazines and related products. Part XV. 2,4-Diaminopyrimidines and 2-aminopyrimidin-4(3H)-ones bearing 1,2,3-benzotriazinyl groups as potential dihydrofolic reductase inhibitors. Brown TB; Stevens MF J Chem Soc Perkin 1; 1975; (11):1023-8. PubMed ID: 1170192 [No Abstract] [Full Text] [Related]
19. Effects of a folic acid antagonist on nucleic acid metabolism. GOLDTHWAIT DA; BENDICH A J Biol Chem; 1952 May; 196(2):841-52. PubMed ID: 12981023 [No Abstract] [Full Text] [Related]
20. Antagonists of nucleic acid derivatives. VIII. Synergism in combinations of biochemically related antimetabolites. ELION GB; SINGER S; HITCHINGS GH J Biol Chem; 1954 Jun; 208(2):477-88. PubMed ID: 13174557 [No Abstract] [Full Text] [Related] [Next] [New Search]