132 related articles for article (PubMed ID: 1304169)
1. (R)-(-)- and (S)-(+)-adenallene: synthesis, absolute configuration, enantioselectivity of antiretroviral effect, and enzymic deamination.
Megati S; Goren Z; Silverton JV; Orlina J; Nishimura H; Shirasaki T; Mitsuya H; Zemlicka J
J Med Chem; 1992 Oct; 35(22):4098-104. PubMed ID: 1304169
[TBL] [Abstract][Full Text] [Related]
2. (R)-(-)- and (S)-(+)-Synadenol: synthesis, absolute configuration, and enantioselectivity of antiviral effect.
Qiu YL; Hempel A; Camerman N; Camerman A; Geiser F; Ptak RG; Breitenbach JM; Kira T; Li L; Gullen E; Cheng YC; Drach JC; Zemlicka J
J Med Chem; 1998 Dec; 41(26):5257-64. PubMed ID: 9857093
[TBL] [Abstract][Full Text] [Related]
3. Phosphodiester amidates of allenic nucleoside analogues: anti-HIV activity and possible mechanism of action.
Winter H; Maeda Y; Mitsuya H; Zemlicka J
J Med Chem; 1996 Aug; 39(17):3300-6. PubMed ID: 8765513
[TBL] [Abstract][Full Text] [Related]
4. Synthesis, absolute configuration, and enantioselectivity of antiretroviral effect of (R)-(-)- and (S)-(+)-cytallene. Lipase-catalyzed enantioselective acylations of (+/-)-N4-acylcytallenes.
Jones BC; Silverton JV; Simons C; Megati S; Nishimura H; Maeda Y; Mitsuya H; Zemlicka J
J Med Chem; 1995 Apr; 38(8):1397-405. PubMed ID: 7731024
[TBL] [Abstract][Full Text] [Related]
5. (Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleoside analogues with a broad-spectrum antiviral activity.
Qiu YL; Ksebati MB; Ptak RG; Fan BY; Breitenbach JM; Lin JS; Cheng YC; Kern ER; Drach JC; Zemlicka J
J Med Chem; 1998 Jan; 41(1):10-23. PubMed ID: 9438017
[TBL] [Abstract][Full Text] [Related]
6. Conformationally locked nucleoside analogues. Synthesis of dideoxycarbocyclic nucleoside analogues structurally related to neplanocin C.
Rodriguez JB; Marquez VE; Nicklaus MC; Mitsuya H; Barchi JJ
J Med Chem; 1994 Sep; 37(20):3389-99. PubMed ID: 7932567
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and enantioselectivity of the antiviral effects of (R,Z)-,(S,Z)-methylenecyclopropane analogues of purine nucleosides and phosphoralaninate prodrugs: influence of heterocyclic base, type of virus and host cells.
Qiu YL; Geiser F; Kira T; Gullen E; Cheng YC; Ptak RG; Breitenbach JM; Drach JC; Hartline CB; Kern ER; Zemlicka J
Antivir Chem Chemother; 2000 May; 11(3):191-202. PubMed ID: 10901290
[TBL] [Abstract][Full Text] [Related]
8. 9-{[3-fluoro-2-(hydroxymethyl)cyclopropylidene]methyl}adenines and -guanines. Synthesis and antiviral activity of all stereoisomers1.
Zhou S; Kern ER; Gullen E; Cheng YC; Drach JC; Tamiya S; Mitsuya H; Zemlicka J
J Med Chem; 2006 Oct; 49(20):6120-8. PubMed ID: 17004726
[TBL] [Abstract][Full Text] [Related]
9. Accumulation and metabolism of adenallene by murine leukemia L1210 cells.
Kessel D; Zemlicka J
Arch Biochem Biophys; 1994 Jan; 308(1):222-5. PubMed ID: 8311456
[TBL] [Abstract][Full Text] [Related]
10. Remarkable acceleration for the deamination of carbocyclic purine nucleosides by adenosine deaminase under high-pressure.
Katagiri N; Shiraishi T; Toyota A; Sato H; Kaneko C
Nucleic Acids Symp Ser; 1993; (29):95-6. PubMed ID: 8247811
[TBL] [Abstract][Full Text] [Related]
11. Adenallene and cytallene: acyclic-nucleoside analogues that inhibit replication and cytopathic effect of human immunodeficiency virus in vitro.
Hayashi S; Phadtare S; Zemlicka J; Matsukura M; Mitsuya H; Broder S
Proc Natl Acad Sci U S A; 1988 Aug; 85(16):6127-31. PubMed ID: 3261865
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and anti-HIV activity of 9-[c-4,t-5-bis(hydroxymethyl)cyclopent-2-en-r-1-yl]-9H-adenine.
Katagiri N; Nomura M; Sato H; Kaneko C; Yusa K; Tsuruo T
J Med Chem; 1992 May; 35(10):1882-6. PubMed ID: 1588565
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and antiviral activity of (Z)- and (E)-2,2-[bis(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines: second-generation methylenecyclopropane analogues of nucleosides.
Zhou S; Breitenbach JM; Borysko KZ; Drach JC; Kern ER; Gullen E; Cheng YC; Zemlicka J
J Med Chem; 2004 Jan; 47(3):566-75. PubMed ID: 14736238
[TBL] [Abstract][Full Text] [Related]
14. Methylenecyclopropane analogues of nucleosides: synthesis, absolute configuration, and enantioselectivity of antiviral effect of (R)-(-)- and (S)-(+)-synadenol.
Qiu YL; Hempel A; Camerman N; Camerman A; Geiser F; Ptak RG; Breitenbach JM; Kira T; Li L; Gullen E; Cheng YC; Drach JC; Zemlicka J
Nucleosides Nucleotides; 1999; 18(4-5):597-8. PubMed ID: 10432651
[TBL] [Abstract][Full Text] [Related]
15. Increase of the adenallene anti-HIV activity in cell culture using its bis(tBuSATE) phosphotriester derivative.
Egron D; Périgaud C; Gosselin G; Aubertin AM; Gatanaga H; Mitsuya H; Zemlicka J; Imbach JL
Bioorg Med Chem Lett; 2002 Jan; 12(2):265-6. PubMed ID: 11755368
[TBL] [Abstract][Full Text] [Related]
16. Synthesis of (Z)- and (E)-9-[(2-hydroxyethylidene)cyclopropyl]adenine--new methylenecyclopropane analogues of adenosine and their substrate activity for adenosine deaminase.
Qui YL; Ksebati MB; Zemlicka J
Nucleosides Nucleotides Nucleic Acids; 2000; 19(1-2):31-7. PubMed ID: 10772701
[TBL] [Abstract][Full Text] [Related]
17. Resolution of racemic carbocyclic analogues of purine nucleosides through the action of adenosine deaminase. Antiviral activity of the carbocyclic 2'-deoxyguanosine enantiomers.
Secrist JA; Montgomery JA; Shealy YF; O'Dell CA; Clayton SJ
J Med Chem; 1987 Apr; 30(4):746-9. PubMed ID: 3031295
[TBL] [Abstract][Full Text] [Related]
18. Enzymatic properties of the unnatural beta-L-enantiomers of 2',3'-dideoxyadenosine and 2',3'-didehydro-2',3'-dideoxyadenosine.
Pélicano H; Pierra C; Eriksson S; Gosselin G; Imbach JL; Maury G
J Med Chem; 1997 Nov; 40(24):3969-73. PubMed ID: 9397178
[TBL] [Abstract][Full Text] [Related]
19. New neplanocin analogues. IX. A practical preparation of (6'R)-6'-C-methylneplanocin A (RMNPA), a potent antiviral agent, and the determination of its 6'-configuration. Diastereoselective deamination by adenosine deaminase.
Shuto S; Obara T; Yaginuma S; Matsuda A
Chem Pharm Bull (Tokyo); 1997 Jan; 45(1):138-42. PubMed ID: 9023976
[TBL] [Abstract][Full Text] [Related]
20. Resolution of 9-(c-4,t-5-bishydroxymethylcyclopent-2-en-r-1-yl)-9H-adenine and selective inhibition of human immunodeficiency virus by the (-) enantiomer.
Katagiri N; Shiraishi T; Sato H; Toyota A; Kaneko C; Yusa K; Oh-hara T; Tsuruo T
Biochem Biophys Res Commun; 1992 Apr; 184(1):154-9. PubMed ID: 1567421
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]